Chemoprevention of colon cancer by calcium, vitamin D and folate: molecular mechanisms (Q35190160)

7 August 2017

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title

Chemoprevention of colon cancer by calcium, vitamin D and folate: molecular mechanisms (English)

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7 August 2017

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Sergio A Lamprecht

1

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PubMed ID

12894248

7 August 2017

Martin Lipkin

series ordinal

2

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PubMed ID

12894248

7 August 2017

language of work or name

English

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publication date

1 August 2003

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7 August 2017

Nature Reviews Cancer

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7 August 2017

3

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7 August 2017

601-614

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7 August 2017

8

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https://scigraph.springernature.com/pub.10.1038/nrc1144

7 August 2017

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cites work

Colorectal cancer: molecules and populations

1 reference

Dietary factors in human colorectal cancer

31 March 2020

1 reference

Epidemiologic studies of folate and colorectal neoplasia: a review

31 March 2020

1 reference

Folate status: effects on pathways of colorectal carcinogenesis

31 March 2020

1 reference

Preclinical mouse models for cancer chemoprevention studies

31 March 2020

1 reference

A Western-style diet induces benign and malignant neoplasms in the colon of normal C57Bl/6 mice

31 March 2020

1 reference

Calcium signalling: dynamics, homeostasis and remodelling

31 March 2020

1 reference

Integration of calcium and Ras signalling.

31 March 2020

1 reference

Cellular mechanisms of calcium and vitamin D in the inhibition of colorectal carcinogenesis

31 March 2020

1 reference

Controlling calcium entry.

31 March 2020

1 reference

Extracellular calcium sensing and extracellular calcium signaling

31 March 2020

1 reference

Cloning and characterization of an extracellular Ca(2+)-sensing receptor from bovine parathyroid

31 March 2020

1 reference

Extracellular cation sensing by the enterocyte: prediction of a novel divalent cation "receptor".

31 March 2020

1 reference

Mechanism of action of the calcium-sensing receptor in human antral gastrin cells

31 March 2020

1 reference

Calcium-dependent c-myc proto-oncogene expression and proliferation of Caco-2 cells: a role for a luminal extracellular calcium-sensing receptor

31 March 2020

1 reference

Immunocytochemical localization of the extracellular calcium-sensing receptor in normal and malignant human large intestinal mucosa.

31 March 2020

1 reference

Activation of protein kinase C isozymes is associated with post-mitotic events in intestinal epithelial cells in situ

31 March 2020

1 reference

Protein kinase C signaling mediates a program of cell cycle withdrawal in the intestinal epithelium

31 March 2020

1 reference

Colonocyte differentiation is associated with increased expression and altered distribution of protein kinase C isozymes.

31 March 2020

1 reference

Activation of protein kinase C modulates cell-cell and cell-substratum adhesion of a human colorectal carcinoma cell line and restores 'normal' epithelial morphology

31 March 2020

1 reference

Protein kinase C alpha modulates growth and differentiation in Caco-2 cells

31 March 2020

1 reference

Protein kinase C isozymes in colon carcinogenesis: guilt by omission.

31 March 2020

1 reference

The effect of extracellular calcium on colonocytes: evidence for differential responsiveness based upon degree of cell differentiation

31 March 2020

1 reference

The effect of dietary vitamin D3 on the intracellular calcium gradient in mammalian colonic crypts

31 March 2020

1 reference

Protein kinase C isozyme-mediated cell cycle arrest involves induction of p21(waf1/cip1) and p27(kip1) and hypophosphorylation of the retinoblastoma protein in intestinal epithelial cells

31 March 2020

1 reference

p27(Kip1) is an inducer of intestinal epithelial cell differentiation

31 March 2020

1 reference

Role of p27(Kip1) in human intestinal cell differentiation

31 March 2020

1 reference

Functional calcium-sensing receptors in rat fibroblasts are required for activation of SRC kinase and mitogen-activated protein kinase in response to extracellular calcium

31 March 2020

1 reference

Intestinal epithelial cell differentiation involves activation of p38 mitogen-activated protein kinase that regulates the homeobox transcription factor CDX2.

31 March 2020

1 reference

Key role of the Cdx2 homeobox gene in extracellular matrix-mediated intestinal cell differentiation

31 March 2020

1 reference

Expression of survivin in normal, hyperplastic, and neoplastic colonic mucosa

31 March 2020

1 reference

Expression of endomembrane calcium pumps in colon and gastric cancer cells. Induction of SERCA3 expression during differentiation

31 March 2020

1 reference

Calcium signaling and apoptosis

31 March 2020

1 reference

Dietary calcium supplementation increases apoptosis in the distal murine colonic epithelium

31 March 2020

1 reference

Distinct functions of nuclear and cytoplasmic calcium in the control of gene expression

31 March 2020

1 reference

Antiproliferative action of vitamin D.

31 March 2020

1 reference

The nuclear vitamin D receptor: biological and molecular regulatory properties revealed.

31 March 2020

1 reference

Vitamin D: more than a "bone-a-fide" hormone.

31 March 2020

1 reference

1,25-Dihydroxyvitamin D3 receptors and human colon adenocarcinoma

31 March 2020

1 reference

Human colon cell line HT-29: characterisation of 1,25-dihydroxyvitamin D3 receptor and induction of differentiation by the hormone

31 March 2020

1 reference

In situ mRNA hybridization analysis and immunolocalization of the vitamin D receptor in normal and carcinomatous human colonic mucosa: relation to epidermal growth factor receptor expression

31 March 2020

1 reference

25-Hydroxyvitamin D(3)-1alpha-hydroxylase and vitamin D receptor gene expression in human colonic mucosa is elevated during early cancerogenesis

31 March 2020

1 reference

A protective role of 1,25-dihydroxyvitamin D3 in chemically induced rat colon carcinogenesis

31 March 2020

1 reference

1,25(OH)2-vitamin D3 receptors: gene regulation and genetic circuitry.

31 March 2020

1 reference

Convergence of transforming growth factor-beta and vitamin D signaling pathways on SMAD transcriptional coactivators

31 March 2020

1 reference

Human calcium-sensing receptor gene. Vitamin D response elements in promoters P1 and P2 confer transcriptional responsiveness to 1,25-dihydroxyvitamin D.

31 March 2020

1 reference

Transcriptional regulation of the ornithine decarboxylase gene by c-Myc/Max/Mad network and retinoblastoma protein interacting with c-Myc

31 March 2020

1 reference

Vitamin D receptor as an intestinal bile acid sensor

31 March 2020

1 reference

Transcriptional control of intestinal cytochrome P-4503A by 1alpha,25-dihydroxy vitamin D3.

31 March 2020

1 reference

The function of vitamin D receptor in vitamin D action

31 March 2020

1 reference

Characterization of a vitamin D receptor knockout mouse as a model of colorectal hyperproliferation and DNA damage

31 March 2020

1 reference

Update on biological actions of 1alpha,25(OH)2-vitamin D3 (rapid effects) and 24R,25(OH)2-vitamin D3.

31 March 2020

1 reference

A specific binding protein/receptor for 1alpha,25-dihydroxyvitamin D(3) is present in an intestinal caveolae membrane fraction

31 March 2020

1 reference

The role of vitamin D in normal and pathologic processes in the colon

31 March 2020

1 reference

Modulation of growth factor/cytokine synthesis and signaling by 1alpha,25-dihydroxyvitamin D(3): implications in cell growth and differentiation

31 March 2020

1 reference

Identification of 1 alpha,25-dihydroxyvitamin D3 response elements in the human transforming growth factor beta 2 gene

31 March 2020

1 reference

A vitamin D3 analog induces a G1-phase arrest in CaCo-2 cells by inhibiting cdk2 and cdk6: roles of cyclin E, p21Waf1, and p27Kip1.

31 March 2020

1 reference

Increased expression of cyclin D1 is an early event in multistage colorectal carcinogenesis.

31 March 2020

1 reference

Vitamin D(3) promotes the differentiation of colon carcinoma cells by the induction of E-cadherin and the inhibition of beta-catenin signaling.

31 March 2020

1 reference

Effects of vitamin D3 derivatives on growth, differentiation and apoptosis in tumoral colonic HT 29 cells: possible implication of intracellular calcium

31 March 2020

1 reference

Methyl supply, methyl metabolizing enzymes and colorectal neoplasia

31 March 2020

1 reference

Folate and carcinogenesis: an integrated scheme

31 March 2020

1 reference

Methylation and colorectal cancer

31 March 2020

1 reference

DNA methylation in health and disease

31 March 2020

1 reference

Impact of folate deficiency on DNA stability

31 March 2020

1 reference

Hypomethylation distinguishes genes of some human cancers from their normal counterparts

31 March 2020

1 reference

Alterations in DNA Methylation: A Fundamental Aspect of Neoplasia

31 March 2020

1 reference

31 March 2020

1 reference

Global and gene-specific methylation patterns in cancer: aspects of tumor biology and clinical potential

31 March 2020

1 reference

Cancer as an epigenetic disease: DNA methylation and chromatin alterations in human tumours

31 March 2020

1 reference

The relationship between hypomethylation and CpG island methylation in colorectal neoplasia

31 March 2020

1 reference

Hypomethylation of ras oncogenes in primary human cancers

31 March 2020

1 reference

DNA hypomethylation leads to elevated mutation rates

31 March 2020

1 reference

Induction of Tumors in Mice by Genomic Hypomethylation

31 March 2020

1 reference

DNMT1 and DNMT3b cooperate to silence genes in human cancer cells

31 March 2020

1 reference

Folate deficiency causes uracil misincorporation into human DNA and chromosome breakage: implications for cancer and neuronal damage

31 March 2020

1 reference

Folate depletion impairs DNA excision repair in the colon of the rat.

31 March 2020

1 reference

Microsatellite instability in non-neoplastic mucosa of patients with ulcerative colitis: effect of folate supplementation

31 March 2020

1 reference

Folate Deficiency In Vitro Induces Uracil Misincorporation and DNA Hypomethylation and Inhibits DNA Excision Repair in Immortalized Normal Human Colon Epithelial Cells

31 March 2020

1 reference

Aging. Increased responsiveness of colorectal mucosa to carcinogen stimulation and protective role of folic acid

31 March 2020

1 reference

Effect of folate supplementation on mucosal cell proliferation in high risk patients for colon cancer

31 March 2020

1 reference

Migrating colonic crypt epithelial cells: primary targets for transformation.

31 March 2020

1 reference

Folic acid inhibition of EGFR-mediated proliferation in human colon cancer cell lines

31 March 2020

1 reference

Effects of dietary folate on DNA strand breaks within mutation-prone exons of the p53 gene in rat colon

31 March 2020

1 reference

The effect of dietary folate on genomic and p53-specific DNA methylation in rat colon

31 March 2020

1 reference

Folate deficiency reduces the development of colorectal cancer in rats

31 March 2020

1 reference

Intake of dietary folate vitamers and risk of colorectal carcinoma: results from The Netherlands Cohort Study

31 March 2020

1 reference

Folate status, genomic DNA hypomethylation, and risk of colorectal adenoma and cancer: a case control study

31 March 2020

1 reference

Methylenetetrahydrofolate reductase polymorphisms, folate, and cancer risk: a paradigm of gene-nutrient interactions in carcinogenesis.

31 March 2020

1 reference

DNA methylation as an intermediate biomarker in colorectal cancer: modulation by folic acid supplementation

31 March 2020

1 reference

The effect of folic acid supplementation on the risk for cancer or dysplasia in ulcerative colitis

31 March 2020

1 reference

Colorectal cancer prevention and treatment by inhibition of cyclooxygenase-2.

31 March 2020

1 reference

Protein kinase C phosphorylation of threonine at position 888 in Ca2+o-sensing receptor (CaR) inhibits coupling to Ca2+ store release

31 March 2020

1 reference

Protein kinase C (PKC) phosphorylation of the Ca2+ o-sensing receptor (CaR) modulates functional interaction of G proteins with the CaR cytoplasmic tail

31 March 2020

1 reference

Ca2+-stimulated Ca2+ oscillations produced by the Ca2+-sensing receptor require negative feedback by protein kinase C.

31 March 2020

1 reference

Folic acid: nutritional biochemistry, molecular biology, and role in disease processes

31 March 2020

1 reference

31 March 2020

1 reference

Genetic effects of methylation diets

31 March 2020

1 reference

Positive and negative modulation of vitamin D receptor function by transforming growth factor-beta signaling through smad proteins

31 March 2020

1 reference

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7 January 2021

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Identifiers

DOI

10.1038/NRC1144

1 reference

7 August 2017

1 reference

PubMed ID

12894248