A faster-acting and more potent form of tissue plasminogen activator (Q35190236)

7 August 2017

A faster-acting and more potent form of tissue plasminogen activator (English)

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7 August 2017

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Keyt BA

1

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7 August 2017

Paoni NF

2

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7 August 2017

Refino CJ

3

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7 August 2017

Berleau L

4

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7 August 2017

Nguyen H

5

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7 August 2017

Chow A

6

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7 August 2017

Lai J

7

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7 August 2017

Peña L

8

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7 August 2017

Pater C

9

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7 August 2017

Ogez J

10

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7 August 2017

language of work or name

English

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publication date

1 April 1994

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Proceedings of the National Academy of Sciences of the United States of America

7 August 2017

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7 August 2017

91

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7 August 2017

9

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7 August 2017

3670-3674

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Receptor-mediated endocytosis of tissue-type plasminogen activator by low density lipoprotein receptor-related protein on human hepatoma HepG2 cells.

7 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43643

Kinetics of the activation of plasminogen by human tissue plasminogen activator. Role of fibrin

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43643

Evolution of the proteases of blood coagulation and fibrinolysis by assembly from modules

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43643

Molecular cloning and expression of human hepatocyte growth factor

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43643

Serpin-resistant mutants of human tissue-type plasminogen activator

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43643

cDNA sequence of rat prothrombin

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43643

Integration, amplification and stability of plasmid sequences in CHO cell cultures

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43643

Deduced primary structure of rat hepatocyte growth factor and expression of the mRNA in rat tissues

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43643

Tissue plasminogen activator: the biochemistry and pharmacology of variants produced by mutagenesis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43643

Amino acid residues that affect interaction of tissue-type plasminogen activator with plasminogen activator inhibitor 1

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43643

Augmented and sustained plasma concentrations after intramuscular injections of molecular variants and deglycosylated forms of tissue-type plasminogen activators

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43643

Hemorrhagic events during therapy with recombinant tissue-type plasminogen activator, heparin, and aspirin for acute myocardial infarction. Results of the Thrombolysis in Myocardial Infarction (TIMI), Phase II Trial

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43643

High resolution analysis of functional determinants on human tissue-type plasminogen activator

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43643

Isolation and characterization of the mannose receptor from human liver potentially involved in the plasma clearance of tissue-type plasminogen activator

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43643

Complexes of tissue-type plasminogen activator and its serpin inhibitor plasminogen-activator inhibitor type 1 are internalized by means of the low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43643

Radioiodination of the active site of tissue plasminogen activator: a method for radiolabeling serine proteases with tyrosylprolylarginyl chloromethyl ketone

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43643

Tyrosine 67 in the epidermal growth factor-like domain of tissue-type plasminogen activator is important for clearance by a specific hepatic receptor

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43643

Crystal structure of the kringle 2 domain of tissue plasminogen activator at 2.4-.ANG. resolution

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43643

Identification of carbohydrate structures in glycoprotein peptide maps by the use of LC/MS with selected ion extraction with special reference to tissue plasminogen activator and a glycosylation variant produced by site directed mutagenesis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43643

Improved thrombolysis with a modified dose regimen of recombinant tissue-type plasminogen activator

27 September 2018

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12 December 2020

Alterations in the domain structure of tissue-type plasminogen activator change the nature of asparagine glycosylation

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12 December 2020

Thrombolytic and pharmacokinetic properties of human tissue-type plasminogen activator variants, obtained by deletion and/or duplication of structural/functional domains, in a hamster pulmonary embolism model

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12 December 2020

Strategies for the improvement of thrombolytic agents

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12 December 2020

Improved thrombolysis in acute myocardial infarction with front-loaded administration of alteplase: results of the rt-PA-APSAC patency study (TAPS)

1 reference

12 December 2020

The amount of plasminogen, tissue-type plasminogen activator and plasminogen activator inhibitor type 1 in human thrombi and the relation to ex-vivo lysibility

1 reference

12 December 2020

Involvement of residues 296-299 in the enzymatic activity of tissue-type plasminogen activator

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12 December 2020

Making tissue-type plasminogen activator more fibrin specific

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12 December 2020

A slow clearing, fibrin-specific, PAI-1 resistant variant of t-PA (T103N, KHRR 296-299 AAAA)

1 reference

12 December 2020

A variant of t-PA (T103N, KHRR 296-299 AAAA) that, by bolus, has increased potency and decreased systemic activation of plasminogen

1 reference

12 December 2020

Clot-selective coronary thrombolysis with tissue-type plasminogen activator

1 reference

12 December 2020

Coronary thrombolysis with tissue-type plasminogen activator in patients with evolving myocardial infarction

1 reference

12 December 2020

Biochemical determinants of clearance of tissue-type plasminogen activator from the circulation

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12 December 2020

The influence of carbohydrate structure on the clearance of recombinant tissue-type plasminogen activator

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12 December 2020

Identifiers

DOI

10.1073/PNAS.91.9.3670

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7 August 2017

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7 August 2017

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