Quantitative prediction of human pharmacokinetics for mAbs exhibiting target-mediated disposition (Q35192878)

7 August 2017

title

Quantitative prediction of human pharmacokinetics for mAbs exhibiting target-mediated disposition (English)

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7 August 2017

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Aman P Singh

1

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7 August 2017

Wojciech Krzyzanski

2

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7 August 2017

Steven W Martin

3

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7 August 2017

Gregory Weber

4

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7 August 2017

Alison Betts

5

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7 August 2017

Alaa Ahmad

6

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7 August 2017

Anson Abraham

7

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7 August 2017

Anup Zutshi

8

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7 August 2017

John Lin

9

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7 August 2017

Pratap Singh

10

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7 August 2017

language of work or name

English

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publication date

3 December 2014

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7 August 2017

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7 August 2017

volume

17

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7 August 2017

issue

2

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7 August 2017

page(s)

389-399

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Prediction of human plasma concentration-time profiles of monoclonal antibodies from monkey data by a species-invariant time method

7 August 2017

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13 July 2018

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13 July 2018

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Interspecies scaling of clearance and volume of distribution data for five therapeutic proteins

13 July 2018

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A model-based approach to predicting the human pharmacokinetics of a monoclonal antibody exhibiting target-mediated drug disposition

13 July 2018

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Quantitative prediction of human pharmacokinetics for monoclonal antibodies: retrospective analysis of monkey as a single species for first-in-human prediction.

27 September 2018

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Translational pharmacokinetics and pharmacodynamics of an FcRn-variant anti-CD4 monoclonal antibody from preclinical model to phase I study

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Prediction of human clearance of therapeutic proteins: simple allometric scaling method revisited.

27 September 2018

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Quasi-equilibrium pharmacokinetic model for drugs exhibiting target-mediated drug disposition.

27 September 2018

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General pharmacokinetic model for drugs exhibiting target-mediated drug disposition

27 September 2018

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Population pharmacokinetics and pharmacodynamics of the anti-CD11a antibody hu1124 in human subjects with psoriasis.

27 September 2018

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Serum levels of interleukin 6 (IL-6), oncostatin M, soluble IL-6 receptor, and soluble gp130 in patients with systemic sclerosis

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Elevated serum levels of interleukin 4 (IL-4), IL-10, and IL-13 in patients with systemic sclerosis

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Differential half-life of major histocompatibility complex encoded class I molecules in T and B lymphoblasts

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Detection of very low receptor numbers on cells by flow cytometry using a sensitive staining method

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The application of target information and preclinical pharmacokinetic/pharmacodynamic modeling in predicting clinical doses of a Dickkopf-1 antibody for osteoporosis

1 reference

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1 reference

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Identifiers

DOI

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Dimensions Publication ID

7 August 2017

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7 August 2017

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