Telomeres are shortened in acinar-to-ductal metaplasia lesions associated with pancreatic intraepithelial neoplasia but not in isolated acinar-to-ductal metaplasias. (Q35194027)

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English	Telomeres are shortened in acinar-to-ductal metaplasia lesions associated with pancreatic intraepithelial neoplasia but not in isolated acinar-to-ductal metaplasias.	scientific article

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14 February 2020

Telomeres are shortened in acinar-to-ductal metaplasia lesions associated with pancreatic intraepithelial neoplasia but not in isolated acinar-to-ductal metaplasias (English)

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14 February 2020

intraepithelial neoplasia

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inferred from title

1

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14 February 2020

Michael Goggins

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Michael Goggins

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14 February 2020

Ralph H. Hruban

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Ralph H Hruban

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14 February 2020

James R Eshleman

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James R Eshleman

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14 February 2020

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Chanjuan Shi

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14 February 2020

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Alan K Meeker

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14 February 2020

Christopher M Heaphy

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Christopher M Heaphy

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14 February 2020

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Soo-Heang Eo

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14 February 2020

HyungJun Cho

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14 February 2020

publication date

24 September 2010

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14 February 2020

number of pages

11

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Modern Pathology

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14 February 2020

24

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14 February 2020

2

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14 February 2020

256-266

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14 February 2020

describes a project that uses

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3166222/fullTextXML

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Beta-catenin blocks Kras-dependent reprogramming of acini into pancreatic cancer precursor lesions in mice

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166222

13 July 2018

Telomeres and telomerase in cancer

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13 July 2018

Dual-label centromere and telomere FISH identifies human, rat, and mouse cell contribution to Multispecies recombinant urogenital sinus xenografts

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Cancer statistics, 2009

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13 July 2018

KRAS2 mutations in human pancreatic acinar-ductal metaplastic lesions are limited to those with PanIN: implications for the human pancreatic cancer cell of origin

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13 July 2018

Spontaneous induction of murine pancreatic intraepithelial neoplasia (mPanIN) by acinar cell targeting of oncogenic Kras in adult mice

1 reference

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13 July 2018

Multiple genes are hypermethylated in intraductal papillary mucinous neoplasms of the pancreas.

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13 July 2018

Update on pancreatic intraepithelial neoplasia.

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13 July 2018

Core signaling pathways in human pancreatic cancers revealed by global genomic analyses

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13 July 2018

Pancreatic cancer.

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13 July 2018

Genome-wide allelotypes of familial pancreatic adenocarcinomas and familial and sporadic intraductal papillary mucinous neoplasms

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13 July 2018

Acinar cells contribute to the molecular heterogeneity of pancreatic intraepithelial neoplasia

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13 July 2018

Multifocal neoplastic precursor lesions associated with lobular atrophy of the pancreas in patients having a strong family history of pancreatic cancer.

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13 July 2018

Identifying allelic loss and homozygous deletions in pancreatic cancer without matched normals using high-density single-nucleotide polymorphism arrays

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13 July 2018

Pathology of genetically engineered mouse models of pancreatic exocrine cancer: consensus report and recommendations.

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13 July 2018

Genome-wide aberrations in pancreatic adenocarcinoma.

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13 July 2018

Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice

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13 July 2018

Telomeres and telomerase: their mechanisms of action and the effects of altering their functions

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13 July 2018

An illustrated consensus on the classification of pancreatic intraepithelial neoplasia and intraductal papillary mucinous neoplasms

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13 July 2018

Large-scale allelotype of pancreaticobiliary carcinoma provides quantitative estimates of genome-wide allelic loss

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13 July 2018

Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse

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13 July 2018

Telomere shortening is an early somatic DNA alteration in human prostate tumorigenesis.

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13 July 2018

Aberrant methylation of the 5' CpG island of TSLC1 is common in pancreatic ductal adenocarcinoma and is first manifest in high-grade PanlNs

1 reference

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13 July 2018

Telomere shortening is nearly universal in pancreatic intraepithelial neoplasia

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166222

13 July 2018

Aberrant methylation of preproenkephalin and p16 genes in pancreatic intraepithelial neoplasia and pancreatic ductal adenocarcinoma

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13 July 2018

Balancing instability: dual roles for telomerase and telomere dysfunction in tumorigenesis

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13 July 2018

Telomere dysfunction triggers extensive DNA fragmentation and evolution of complex chromosome abnormalities in human malignant tumors

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13 July 2018

Telomere dysfunction and evolution of intestinal carcinoma in mice and humans

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13 July 2018

Pancreatic intraepithelial neoplasia: a new nomenclature and classification system for pancreatic duct lesions

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166222

13 July 2018

Allelic loss is often the first hit in the biallelic inactivation of the p53 and DPC4 genes during pancreatic carcinogenesis

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166222

13 July 2018

Telomere biology in human aging and aging syndromes

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13 July 2018

Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166222

13 July 2018

BRCA2 is inactivated late in the development of pancreatic intraepithelial neoplasia: evidence and implications

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Creation of human tumour cells with defined genetic elements

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CpG island methylation profile of pancreatic intraepithelial neoplasia

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27 September 2018

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Telomere dysfunction provokes regional amplification and deletion in cancer genomes.

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Uremic exocrine pancreopathy

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12 December 2020

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Consistent chromosome abnormalities in adenocarcinoma of the pancreas

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12 December 2020

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Chronic Pancreatitis Is Essential for Induction of Pancreatic Ductal Adenocarcinoma by K-Ras Oncogenes in Adult Mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20871595

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p16 and K-ras gene mutations in the intraductal precursors of human pancreatic adenocarcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/20871595

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of expression of Dpc4 in pancreatic intraepithelial neoplasia: evidence that DPC4 inactivation occurs late in neoplastic progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/20871595

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A case of mistaken identity? Nonductal origins of pancreatic "ductal" cancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/20871595

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Familial pancreatic cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/20871595

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/MODPATHOL.2010.181

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14 February 2020

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14 February 2020

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14 February 2020

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