Antioxidative flavonoid quercetin: implication of its intestinal absorption and metabolism (Q35201098)

7 August 2017

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title

Antioxidative flavonoid quercetin: implication of its intestinal absorption and metabolism (English)

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7 August 2017

Kaeko Murota

1

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PubMed ID

12921774

7 August 2017

Junji Terao

series ordinal

2

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PubMed ID

12921774

7 August 2017

language of work or name

English

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publication date

1 September 2003

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Archives of Biochemistry and Biophysics

7 August 2017

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7 August 2017

417

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7 August 2017

1

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7 August 2017

12-17

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Absorption, metabolism and health effects of dietary flavonoids in man

7 August 2017

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https://api.crossref.org/works/10.1016%2FS0003-9861%2803%2900284-4

Potential health impacts of excessive flavonoid intake

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0003-9861%2803%2900284-4

Flavonoid in Fruits and Vegetables. Part II. Content of Flavonol Glucosides and Some Properties of Enzymes Metabolizing the Glucosides in Onion.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2803%2900284-4

Dietary flavonoids: bioavailability, metabolic effects, and safety

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2803%2900284-4

Review of the biology of Quercetin and related bioflavonoids

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2803%2900284-4

Flavonoids as antioxidants: determination of radical-scavenging efficiencies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2803%2900284-4

Structure-antioxidant activity relationships of flavonoids and phenolic acids

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0003-9861%2803%2900284-4

Structural dependence of flavonoid interactions with Cu2+ ions: implications for their antioxidant properties

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0003-9861%2803%2900284-4

Flavonoids and membrane lipid peroxidation inhibition

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0003-9861%2803%2900284-4

Inhibitory effect of quercetin metabolites and their related derivatives on copper ion-induced lipid peroxidation in human low-density lipoprotein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2803%2900284-4

Antioxidative activity of quercetin and quercetin monoglucosides in solution and phospholipid bilayers

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2803%2900284-4

Dietary intake and bioavailability of polyphenols

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0003-9861%2803%2900284-4

Quercetin metabolites inhibit copper ion-induced lipid peroxidation in rat plasma

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0003-9861%2803%2900284-4

The identification of flavonoids as glycosides in human plasma

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0003-9861%2803%2900284-4

Absorption and excretion of conjugated flavonols, including quercetin-4'-O-beta-glucoside and isorhamnetin-4'-O-beta-glucoside by human volunteers after the consumption of onions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2803%2900284-4

Quercetin is recovered in human plasma as conjugated derivatives which retain antioxidant properties

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0003-9861%2803%2900284-4

Quercetin 3-O-beta-glucoside is better absorbed than other quercetin forms and is not present in rat plasma

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0003-9861%2803%2900284-4

Quercetin glucuronides but not glucosides are present in human plasma after consumption of quercetin-3-glucoside or quercetin-4'-glucoside

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2803%2900284-4

Identification of quercetin 3-O-beta-D-glucuronide as an antioxidative metabolite in rat plasma after oral administration of quercetin

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0003-9861%2803%2900284-4

Identification of quercetin glucuronides in human plasma by high-performance liquid chromatography-tandem mass spectrometry.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2803%2900284-4

Human metabolism of dietary flavonoids: identification of plasma metabolites of quercetin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2803%2900284-4

Determination of flavonol metabolites in plasma and tissues of rats by HPLC-radiocounting and tandem mass spectrometry following oral ingestion of [2-(14)C]quercetin-4'-glucoside.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2803%2900284-4

Protection by quercetin and quercetin 3-O-beta-D-glucuronide of peroxynitrite-induced antioxidant consumption in human plasma low-density lipoprotein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2803%2900284-4

Inhibitory effect of a quercetin metabolite, quercetin 3-O-beta-D-glucuronide, on lipid peroxidation in liposomal membranes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2803%2900284-4

Effect of quercetin and its conjugated metabolite on the hydrogen peroxide-induced intracellular production of reactive oxygen species in mouse fibroblasts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2803%2900284-4

Quercetin glucuronide prevents VSMC hypertrophy by angiotensin II via the inhibition of JNK and AP-1 signaling pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2803%2900284-4

Flavonoid glucuronides are substrates for human liver beta-glucuronidase

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0003-9861%2803%2900284-4

Metabolism of quercetin-7- and quercetin-3-glucuronides by an in vitro hepatic model: the role of human beta-glucuronidase, sulfotransferase, catechol-O-methyltransferase and multi-resistant protein 2 (MRP2) in flavonoid metabolism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2803%2900284-4

Carbon dioxide is the major metabolite of quercetin in humans

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0003-9861%2803%2900284-4

Hydrolysis of dietary flavonoid glycosides by strains of intestinal Bacteroides from humans

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0003-9861%2803%2900284-4

Absorption of dietary quercetin glycosides and quercetin in healthy ileostomy volunteers

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0003-9861%2803%2900284-4

Quercetin glucosides are completely hydrolyzed in ileostomy patients before absorption

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0003-9861%2803%2900284-4

beta-Glucosidase activity in the rat small intestine toward quercetin monoglucosides

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0003-9861%2803%2900284-4

Deglycosylation of flavonoid and isoflavonoid glycosides by human small intestine and liver beta-glucosidase activity

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0003-9861%2803%2900284-4

Dietary flavonoid and isoflavone glycosides are hydrolysed by the lactase site of lactase phlorizin hydrolase

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0003-9861%2803%2900284-4

The sugar moiety is a major determinant of the absorption of dietary flavonoid glycosides in man

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0003-9861%2803%2900284-4

Bioavailabilities of quercetin-3-glucoside and quercetin-4'-glucoside do not differ in humans

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2803%2900284-4

Efficiency of absorption and metabolic conversion of quercetin and its glucosides in human intestinal cell line Caco-2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2803%2900284-4

Unique uptake and transport of isoflavone aglycones by human intestinal caco-2 cells: comparison of isoflavonoids and flavonoids.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2803%2900284-4

Absence of HeLa cell contamination in 169 cell lines derived from human tumors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2803%2900284-4

Lysophosphatidylcholine enhances carotenoid uptake from mixed micelles by Caco-2 human intestinal cells

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0003-9861%2803%2900284-4

Transport of quercetin and its glucosides across human intestinal epithelial Caco-2 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2803%2900284-4

Intestinal transport of quercetin glycosides in rats involves both deglycosylation and interaction with the hexose transport pathway

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0003-9861%2803%2900284-4

Comparison of the intestinal absorption of quercetin, phloretin and their glucosides in rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2803%2900284-4

Absorption of quercetin-3-glucoside and quercetin-4'-glucoside in the rat small intestine: the role of lactase phlorizin hydrolase and the sodium-dependent glucose transporter

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2803%2900284-4

Accumulation of (-)-epicatechin metabolites in rat plasma after oral administration and distribution of conjugation enzymes in rat tissues

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2803%2900284-4

UDP-glucuronosyltransferases in human intestinal mucosa

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2803%2900284-4

Sulphation of resveratrol, a natural product present in grapes and wine, in the human liver and duodenum

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2803%2900284-4

Substrate specificity and some properties of phenol sulfotransferase from human intestinal Caco-2 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2803%2900284-4

Glucuronidation in the Caco-2 human intestinal cell line: induction of UDP-glucuronosyltransferase 1*6.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2803%2900284-4

Combination of lipids and emulsifiers enhances the absorption of orally administered quercetin in rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2803%2900284-4

Red wine is a poor source of bioavailable flavonols in men

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0003-9861%2803%2900284-4

Addition of milk does not affect the absorption of flavonols from tea in man.

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0003-9861%2803%2900284-4

Quercetin may act as a cytotoxic prooxidant after its metabolic activation to semiquinone and quinoidal product

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0003-9861%2803%2900284-4

Mechanism of oxidative DNA damage induced by quercetin in the presence of Cu(II).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2803%2900284-4

10.1016/S0003-9861(03)00284-4

7 January 2021

Identifiers

DOI

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7 August 2017

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PubMed ID

12921774