Efficacy and safety of dietary supplements containing CLA for the treatment of obesity: evidence from animal and human studies (Q35201279)

7 August 2017

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title

Efficacy and safety of dietary supplements containing CLA for the treatment of obesity: evidence from animal and human studies (English)

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7 August 2017

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3

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author name string

Thomas M Larsen

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1

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PubMed ID

12923219

7 August 2017

Soren Toubro

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2

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7 August 2017

16 August 2003

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Journal of Lipid Research

7 August 2017

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7 August 2017

44

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7 August 2017

12

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7 August 2017

2234-2241

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Conjugated linoleic acid decreases fat accretion in pigs: evaluation by dual-energy X-ray absorptiometry

7 August 2017

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R300011-JLR200

Evidence that the trans-10,cis-12 isomer of conjugated linoleic acid induces body composition changes in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R300011-JLR200

Isomer-specific antidiabetic properties of conjugated linoleic acid. Improved glucose tolerance, skeletal muscle insulin action, and UCP-2 gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R300011-JLR200

Dietary CLA alters yolk and tissue FA composition and hepatic histopathology of laying hens

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R300011-JLR200

Conjugated linoleic acid activates peroxisome proliferator-activated receptor alpha and beta subtypes but does not induce hepatic peroxisome proliferation in Sprague-Dawley rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R300011-JLR200

Isomer-specific actions of conjugated linoleic acid on muscle glucose transport in the obese Zucker rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R300011-JLR200

Dietary supplementation with conjugated linoleic acid does not improve nutritional status of tumor-bearing rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R300011-JLR200

Isomer-dependent metabolic effects of conjugated linoleic acid: insights from molecular markers sterol regulatory element-binding protein-1c and LXRalpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R300011-JLR200

Conjugated linoleic acid supplementation reduces adipose tissue by apoptosis and develops lipodystrophy in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R300011-JLR200

Dietary trans-10,cis-12 conjugated linoleic acid induces hyperinsulinemia and fatty liver in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R300011-JLR200

Association of liver steatosis with lipid oversecretion and hypotriglyceridaemia in C57BL/6j mice fed trans-10,cis-12-linoleic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R300011-JLR200

Activity and mRNA levels of enzymes involved in hepatic fatty acid synthesis and oxidation in mice fed conjugated linoleic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R300011-JLR200

Conjugated linoleic acid depresses the delta9 desaturase index and stearoyl coenzyme A desaturase enzyme activity in porcine subcutaneous adipose tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R300011-JLR200

trans-10, cis-12 conjugated linoleic acid decreases lipogenic rates and expression of genes involved in milk lipid synthesis in dairy cows.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R300011-JLR200

Short communication: milk fat response to low doses of tran-10, cis-12 conjugated linoleic acid (CLA).

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R300011-JLR200

Maternal supplementation with CLA decreases milk fat in humans

21 January 2018

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https://api.crossref.org/works/10.1194%2FJLR.R300011-JLR200

Loss of stearoyl-CoA desaturase-1 function protects mice against adiposity

21 January 2018

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https://api.crossref.org/works/10.1194%2FJLR.R300011-JLR200

Adipose depletion and apoptosis induced by trans-10, cis-12 conjugated linoleic Acid in mice

21 January 2018

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https://api.crossref.org/works/10.1194%2FJLR.R300011-JLR200

Isomer-specific regulation of metabolism and PPARgamma signaling by CLA in human preadipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R300011-JLR200

trans-10,cis-12 CLA inhibits differentiation of 3T3-L1 adipocytes and decreases PPAR gamma expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R300011-JLR200

Trans10, cis12-conjugated linoleic acid prevents triacylglycerol accumulation in adipocytes by acting as a PPARγ modulator

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R300011-JLR200

Treatment with dietary trans10cis12 conjugated linoleic acid causes isomer-specific insulin resistance in obese men with the metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R300011-JLR200

Supplementation with conjugated linoleic acid causes isomer-dependent oxidative stress and elevated C-reactive protein: a potential link to fatty acid-induced insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R300011-JLR200

Trans fatty acids and coronary heart disease.

21 January 2018

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https://api.crossref.org/works/10.1194%2FJLR.R300011-JLR200

Cell membrane trans-fatty acids and the risk of primary cardiac arrest

21 January 2018

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https://api.crossref.org/works/10.1194%2FJLR.R300011-JLR200

Conjugated linoleic acid may be useful in treating diabetes by controlling body fat and weight gain

21 January 2018

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https://api.crossref.org/works/10.1194%2FJLR.R300011-JLR200

Thiazolidinediones increase plasma-adipose tissue FFA exchange capacity and enhance insulin-mediated control of systemic FFA availability

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R300011-JLR200

Increased fatty acid re-esterification by PEPCK overexpression in adipose tissue leads to obesity without insulin resistance

21 January 2018

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https://api.crossref.org/works/10.1194%2FJLR.R300011-JLR200

Tissue-specific overexpression of lipoprotein lipase causes tissue-specific insulin resistance

21 January 2018

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https://api.crossref.org/works/10.1194%2FJLR.R300011-JLR200

Changes in conjugated linoleic acid composition within samples obtained from a single source

21 January 2018

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https://api.crossref.org/works/10.1194%2FJLR.R300011-JLR200

Clinical trial results support a preference for using CLA preparations enriched with two isomers rather than four isomers in human studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R300011-JLR200

Conjugated linoleic acid supplementation in humans: effects on body composition and energy expenditure

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R300011-JLR200

The effect of conjugated linoleic acid on plasma lipoproteins and tissue fatty acid composition in humans

21 January 2018

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https://api.crossref.org/works/10.1194%2FJLR.R300011-JLR200

Conjugated linoleic acid reduces body fat in healthy exercising humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R300011-JLR200

Conjugated linoleic acid supplementation in humans--metabolic effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R300011-JLR200

High-fat dairy product consumption increases Δ9c’ 11t−18∶2 (rumenic acid) and total lipid concentrations of human milk

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R300011-JLR200

Conjugated linoleic acid modulates hepatic lipid composition in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R300011-JLR200

Effect of dietary conjugated linoleic acid on lipid peroxidation and histological change in rat liver tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R300011-JLR200

Investigation of the potential of conjugated linoleic acid (Cla) to cause peroxisome proliferation in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R300011-JLR200

Dietary conjugated linoleic acids promote fatty streak formation in the C57BL/6 mouse atherosclerosis model

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R300011-JLR200

Dietary conjugated linoleic acid normalizes impaired glucose tolerance in the Zucker diabetic fatty fa/fa rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R300011-JLR200

Conjugated linoleic acid decreases hepatic stearoyl-CoA desaturase mRNA expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R300011-JLR200

The effect of conjugated linoleic acid supplementation after weight loss on body weight regain, body composition, and resting metabolic rate in overweight subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R300011-JLR200

Conjugated linoleic acid induces lipid peroxidation in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R300011-JLR200

PPARgamma agonists in the treatment of type II diabetes: is increased fatness commensurate with long-term efficacy?

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R300011-JLR200

Effect of supplementation with conjugated linoleic acid on human serum lipids and body fat

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R300011-JLR200

Conjugated linoleic acid (CLA) reduced abdominal adipose tissue in obese middle-aged men with signs of the metabolic syndrome: a randomised controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R300011-JLR200

Effects of conjugated linoleic acid supplementation during resistance training on body composition, bone density, strength, and selected hematological markers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R300011-JLR200

10.1194/JLR.R300011-JLR200

21 January 2018

Identifiers

DOI

1 reference

7 August 2017

1 reference

PubMed ID

12923219