Activity of the non-steroidal anti-inflammatory drug indomethacin against colorectal cancer (Q35202902)

7 August 2017

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title

Activity of the non-steroidal anti-inflammatory drug indomethacin against colorectal cancer (English)

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7 August 2017

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1 reference

Hull MA

1

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PubMed ID

12927571

7 August 2017

Gardner SH

series ordinal

2

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PubMed ID

12927571

7 August 2017

Hawcroft G

series ordinal

3

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7 August 2017

1 August 2003

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7 August 2017

Cancer Treatment Reviews

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7 August 2017

29

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7 August 2017

309-320

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7 August 2017

4

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Indomethacin and ascorbate inhibit desmoid tumors

7 August 2017

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7 January 2021

Nonsteroid antiinflammatory drugs and tamoxifen for desmoid tumors and carcinoma of the stomach

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7 January 2021

Sulindac for polyposis of the colon

1 reference

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7 January 2021

Treatment of colonic and rectal adenomas with sulindac in familial adenomatous polyposis

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7 January 2021

Randomized controlled trial of the effect of sulindac on duodenal and rectal polyposis and cell proliferation in patients with familial adenomatous polyposis.

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7 January 2021

Primary chemoprevention of familial adenomatous polyposis with sulindac

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7 January 2021

Regression of rectal polyps by indomethacin suppository in familial adenomatous polyposis. Report of two cases

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7 January 2021

Regression of Head and Neck Carcinoma With a Prostaglandin-Synthesis Inhibitor

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7 January 2021

Skin cancers in xeroderma pigmentosum: response to indomethacin and steroids

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7 January 2021

Effect of indomethacin plus ranitidine in advanced melanoma patients on high-dose interleukin-2

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7 January 2021

Anti-lymphoma effect of naproxen and indomethacin in a patient with relapsed diffuse large B-cell lymphoma

1 reference

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7 January 2021

Ester and amide derivatives of the nonsteroidal antiinflammatory drug, indomethacin, as selective cyclooxygenase-2 inhibitors

1 reference

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7 January 2021

Biochemically based design of cyclooxygenase-2 (COX-2) inhibitors: facile conversion of nonsteroidal antiinflammatory drugs to potent and highly selective COX-2 inhibitors

1 reference

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7 January 2021

Lack of gastric toxicity of nitric oxide-releasing indomethacin, NCX-530, in experimental animals

1 reference

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7 January 2021

Reduced risk of colorectal cancer among long-term users of aspirin and nonaspirin nonsteroidal antiinflammatory drugs

1 reference

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7 January 2021

Nonsteroidal anti-inflammatory drugs and colorectal cancer: evolving concepts of their chemopreventive actions

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7 January 2021

Inhibition of NF-kappaB and AP-1 activation by R- and S-flurbiprofen

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7 January 2021

The use of anti-inflammatory drugs in cancer pain

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7 January 2021

Inhibition of initiation and promotion by N-methylnitrosourea-induced colon carcinogenesis in rats by non-steroid anti-inflammatory agent indomethacin.

1 reference

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7 January 2021

Reduced incidence of colorectal adenoma among long-term users of nonsteroidal antiinflammatory drugs: a pooled analysis of published studies and a new population-based study

1 reference

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7 January 2021

Interleukin 12 and indomethacin exert a synergistic, angiogenesis-dependent antitumor activity in mice

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7 January 2021

Discordant effect of aspirin and indomethacin on intestinal tumor burden in Apc(Min/+)mice

1 reference

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7 January 2021

Non-steroidal anti-inflammatory drugs with different cyclooxygenase inhibitory profiles that prevent aberrant crypt foci formation but vary in acute gastrotoxicity in a rat model

1 reference

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7 January 2021

Sulindac and indomethacin inhibit formation of aberrant crypt foci in the colons of dimethyl hydrazine treated rats.

1 reference

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7 January 2021

Aspirin, but not sodium salicylate, indomethacin, or nabumetone, reversibly suppresses 1,2-dimethylhydrazine-induced colonic aberrant crypt foci in rats

1 reference

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7 January 2021

Non-steroidal anti-inflammatory drugs with activity against either cyclooxygenase 1 or cyclooxygenase 2 inhibit colorectal cancer in a DMH rodent model by inducing apoptosis and inhibiting cell proliferation

1 reference

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7 January 2021

Prevention of colon polyposis and carcinomas by right hemicolectomy and indomethacin in animal model.

1 reference

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7 January 2021

Influence of indomethacin and difluoromethylornithine on human tumour growth in nude mice

1 reference

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7 January 2021

Further studies on the therapeutic effect of indomethacin on esophageal tumors

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7 January 2021

Mechanism of inhibition of tumour growth by aspirin and indomethacin

1 reference

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7 January 2021

Alteration of tumor growth by aspirin and indomethacin: studies with two transplantable tumors in mouse

1 reference

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7 January 2021

Non-steroidol anti-inflammatory drug effect on crypt cell proliferation and apoptosis during initiation of rat colon carcinogenesis

1 reference

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7 January 2021

Nonsteroidal antiinflammatory drugs inhibit the proliferation of colon adenocarcinoma cells: effects on cell cycle and apoptosis

1 reference

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7 January 2021

Apoptosis induced by NS-398, a selective cyclooxygenase-2 inhibitor, in human colorectal cancer cell lines.

1 reference

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7 January 2021

The effect of non-steroidal anti-inflammatory drugs on human colorectal cancer cells: evidence of different mechanisms of action.

1 reference

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7 January 2021

Cyclooxygenase-2-selective antagonists do not inhibit growth of colorectal carcinoma cell lines

1 reference

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7 January 2021

Induction of apoptosis in colon cancer cells by nonsteroidal anti-inflammatory drugs

1 reference

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7 January 2021

Nonsteroidal anti-inflammatory drugs stimulate spermidine/spermine acetyltransferase and deplete polyamine content in colon cancer cells.

1 reference

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7 January 2021

Effect of the nonsteroidal anti-inflammatory drug indomethacin on proliferation and apoptosis of colon carcinoma cells.

1 reference

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7 January 2021

Mechanisms underlying nonsteroidal antiinflammatory drug-mediated apoptosis

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7 January 2021

Role of BAX in the apoptotic response to anticancer agents

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7 January 2021

Prolonged activation of mitogen-activated protein kinases during NSAID-induced apoptosis in HT-29 colon cancer cells

1 reference

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7 January 2021

Lack of cyclooxygenase-2 activity in HT-29 human colorectal carcinoma cells

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7 January 2021

Effect of prostaglandin E(2) on the proliferation, Ca(2+) mobilization and cAMP in HT-29 human colon adenocarcinoma cells

1 reference

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7 January 2021

The effects of dipyridamole and indomethacin on methotrexate cytotoxicity in LoVo human colon cancer cells

1 reference

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7 January 2021

Evidences for involvement of cyclooxygenase-2 in proliferation of two gastrointestinal cancer cell lines

1 reference

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7 January 2021

Nonsteroidal anti-inflammatory drugs attenuate epidermal growth factor-induced proliferation independent of prostaglandin synthesis inhibition

1 reference

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7 January 2021

Sulindac sulfide, an aspirin-like compound, inhibits proliferation, causes cell cycle quiescence, and induces apoptosis in HT-29 colon adenocarcinoma cells

1 reference

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7 January 2021

Effects of nonsteroidal anti-inflammatory drugs on proliferation and on induction of apoptosis in colon cancer cells by a prostaglandin-independent pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS0305-7372%2803%2900014-8

7 January 2021

Effect of aspirin on induction of apoptosis in HT-29 human colon adenocarcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0305-7372%2803%2900014-8

7 January 2021

The effect of selective cyclooxygenase inhibitors on intestinal epithelial cell mitogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0305-7372%2803%2900014-8

7 January 2021

Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: a full in vitro analysis

1 reference

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7 January 2021

Interpreting the clinical significance of the differential inhibition of cyclooxygenase-1 and cyclooxygenase-2.

1 reference

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7 January 2021

Kinetic basis for selective inhibition of cyclo-oxygenases

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7 January 2021

The analysis of nonsteroidal antiinflammatory drug selectivity in prostaglandin G/H synthase (PGHS)-null cells

1 reference

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7 January 2021

Colorectal cancer prevention and treatment by inhibition of cyclooxygenase-2.

1 reference

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7 January 2021

The role of cyclooxygenase inhibition in the antineoplastic effects of nonsteroidal antiinflammatory drugs (NSAIDs)

1 reference

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7 January 2021

Prostaglandin E2 increases growth and motility of colorectal carcinoma cells

1 reference

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7 January 2021

Malignant transformation and antineoplastic actions of nonsteroidal antiinflammatory drugs (NSAIDs) on cyclooxygenase-null embryo fibroblasts

1 reference

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7 January 2021

Localization of cyclooxygenase-2 in human sporadic colorectal adenomas

1 reference

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7 January 2021

Host cyclooxygenase-2 modulates carcinoma growth.

1 reference

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7 January 2021

Acceleration of intestinal polyposis through prostaglandin receptor EP2 in Apc(Delta 716) knockout mice

1 reference

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7 January 2021

Paracrine cyclooxygenase-2-mediated signalling by macrophages promotes tumorigenic progression of intestinal epithelial cells

1 reference

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7 January 2021

Peroxisome proliferator-activated receptors alpha and gamma are activated by indomethacin and other non-steroidal anti-inflammatory drugs

1 reference

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7 January 2021

Nonsteroidal anti-inflammatory drugs induce apoptosis in association with activation of peroxisome proliferator-activated receptor gamma in rheumatoid synovial cells

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7 January 2021

Activation of peroxisome proliferator-activated receptor isoforms and inhibition of prostaglandin H(2) synthases by ibuprofen, naproxen, and indomethacin

1 reference

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7 January 2021

Diclofenac antagonizes peroxisome proliferator-activated receptor-gamma signaling

1 reference

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7 January 2021

Activation of PPARgamma leads to inhibition of anchorage-independent growth of human colorectal cancer cells

1 reference

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7 January 2021

Characteristics of the peroxisome proliferator activated receptor gamma (PPARgamma) ligand induced apoptosis in colon cancer cells

1 reference

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7 January 2021

Controversy: PPARgamma as a target for treatment of colorectal cancer

1 reference

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7 January 2021

Linking colorectal cancer to Wnt signaling

1 reference

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7 January 2021

Beta-catenin--a linchpin in colorectal carcinogenesis?

1 reference

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7 January 2021

Variable beta-catenin expression in colorectal cancers indicates tumor progression driven by the tumor environment

1 reference

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7 January 2021

Indomethacin induces differential expression of beta-catenin, gamma-catenin and T-cell factor target genes in human colorectal cancer cells

1 reference

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7 January 2021

Inhibition of beta-catenin translocation in rodent colorectal tumors: a novel explanation for the protective effect of nonsteroidal antiinflammatory drugs in colorectal cancer

1 reference

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7 January 2021

Relationship of beta-catenin and Bcl-2 expression to sulindac-induced regression of intestinal tumors in Min mice

1 reference

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7 January 2021

The nonsteroidal anti-inflammatory drugs aspirin and indomethacin attenuate beta-catenin/TCF-4 signaling

1 reference

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7 January 2021

Phosphorylation of glycogen synthase kinase-3 and stimulation of T-cell factor signaling following activation of EP2 and EP4 prostanoid receptors by prostaglandin E2.

1 reference

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7 January 2021

Repression of cyclin D1: a novel function of MYC

1 reference

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7 January 2021

Nonsteroidal anti-inflammatory drugs, short-chain fatty acids, and reactive oxygen metabolism in human colorectal cancer cells

1 reference

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7 January 2021

Transcriptional induction of Nur77 by indomethacin that results in apoptosis of colon cancer cells

1 reference

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7 January 2021

Cyclooxygenase inhibitors regulate the expression of a TGF-beta superfamily member that has proapoptotic and antitumorigenic activities.

1 reference

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7 January 2021

Expression and regulation of nonsteroidal anti-inflammatory drug-activated gene (NAG-1) in human and mouse tissue.

1 reference

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7 January 2021

Dual function of nonsteroidal anti-inflammatory drugs (NSAIDs): inhibition of cyclooxygenase and induction of NSAID-activated gene

1 reference

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7 January 2021

Indomethacin in submicromolar concentrations inhibits cyclic AMP-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0305-7372%2803%2900014-8

7 January 2021

Non-steroidal anti-inflammatory drug-induced apoptosis in gastric cancer cells is blocked by protein kinase C activation through inhibition of c-myc

1 reference

https://api.crossref.org/works/10.1016%2FS0305-7372%2803%2900014-8

7 January 2021

Overexpression of protein kinase C-beta1 isoenzyme suppresses indomethacin-induced apoptosis in gastric epithelial cells

1 reference

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7 January 2021

Cutting edge: agonistic effect of indomethacin on a prostaglandin D2 receptor, CRTH2

1 reference

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7 January 2021

Dysregulation of integrin-linked kinase (ILK) signaling in colonic polyposis

1 reference

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7 January 2021

Cancer research. Anti-inflammatories inhibit cancer growth--but how?

1 reference

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7 January 2021

Kinetics of indomethacin absorption, elimination, and enterohepatic circulation in man

1 reference

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7 January 2021

High expression of cyclooxygenase-2 in macrophages of human colonic adenoma.

1 reference

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7 January 2021

NF-kappaB, p38 MAPK and JNK are highly expressed and active in the stroma of human colonic adenomatous polyps

1 reference

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7 January 2021

MIC-1, a novel macrophage inhibitory cytokine, is a divergent member of the TGF-beta superfamily

1 reference

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7 January 2021

Clonogenic inactivation of colon cancer-derived cells treated with 5-fluorouracil and indomethacin in hybrid spheroids

1 reference

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7 January 2021

Synergistic effect of indomethacin and bleomycin on tumor growth produced by activating antitumor immunity

1 reference

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7 January 2021

Synergistic effect of indomethacin with adriamycin and cisplatin on tumor growth

1 reference

https://api.crossref.org/works/10.1016%2FS0305-7372%2803%2900014-8

7 January 2021

Variability in risk of gastrointestinal complications with individual non-steroidal anti-inflammatory drugs: results of a collaborative meta-analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0305-7372%2803%2900014-8

7 January 2021

Lack of small intestinal ulcerogenecity of nitric oxide-releasing indomethacin, NCX-530, in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0305-7372%2803%2900014-8

7 January 2021

Cyclooxygenase-independent chemoprevention with an aspirin derivative in a rat model of colonic adenocarcinoma.

1 reference

https://api.crossref.org/works/10.1016%2FS0305-7372%2803%2900014-8

7 January 2021

10.1016/S0305-7372(03)00014-8

Identifiers

DOI

1 reference

7 August 2017

1 reference

PubMed ID

12927571