Stearoyl-CoA desaturase 1 activity is required for autophagosome formation (Q35206722)

7 August 2017

Stearoyl-CoA desaturase 1 activity is required for autophagosome formation (English)

1 reference

7 August 2017

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2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25023287%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Mizushima Noboru

4

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12 June 2020

author name string

Yuta Ogasawara

1

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12 June 2020

Nozomu Kono

3

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12 June 2020

Hiroyuki Arai

5

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12 June 2020

Atsuki Nara

6

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12 June 2020

Tamio Mizukami

7

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12 June 2020

Akitsugu Yamamoto

8

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12 June 2020

language of work or name

English

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publication date

14 July 2014

1 reference

Journal of Biological Chemistry

7 August 2017

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12 June 2020

volume

289

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12 June 2020

issue

34

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12 June 2020

page(s)

23938-23950

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Lipidation of the LC3/GABARAP family of autophagy proteins relies on a membrane-curvature-sensing domain in Atg3.

12 June 2020

cites work

1 reference

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Expression of the autophagy substrate SQSTM1/p62 is restored during prolonged starvation depending on transcriptional upregulation and autophagy-derived amino acids

28 July 2018

1 reference

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Critical role of SCD1 in autophagy regulation via lipogenesis and lipid rafts-coupled AKT-FOXO1 signaling pathway.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156085

Autophagosomes form at ER-mitochondria contact sites

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156085

Architecture of the Atg17 Complex as a Scaffold for Autophagosome Biogenesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156085

Differential roles of unsaturated and saturated fatty acids on autophagy and apoptosis in hepatocytes

28 July 2018

1 reference

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Docosahexaenoic acid induces autophagy through p53/AMPK/mTOR signaling and promotes apoptosis in human cancer cells harboring wild-type p53

28 July 2018

1 reference

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Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling

28 July 2018

1 reference

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AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156085

p62 Targeting to the autophagosome formation site requires self-oligomerization but not LC3 binding

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156085

Autophagy requires endoplasmic reticulum targeting of the PI3-kinase complex via Atg14L.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156085

Characterization of autophagosome formation site by a hierarchical analysis of mammalian Atg proteins

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156085

Autophagy: assays and artifacts

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156085

A subdomain of the endoplasmic reticulum forms a cradle for autophagosome formation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156085

A novel, human Atg13 binding protein, Atg101, interacts with ULK1 and is essential for macroautophagy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156085

Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156085

Biochemical and physiological function of stearoyl-CoA desaturase

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156085

Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156085

Autophagy fights disease through cellular self-digestion

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156085

Discovery of potent, selective, orally bioavailable stearoyl-CoA desaturase 1 inhibitors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156085

Starvation and ULK1-dependent cycling of mammalian Atg9 between the TGN and endosomes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156085

Autophagy: a forty-year search for a missing membrane source

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156085

p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156085

The expanding TOR signaling network

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156085

WIPI-1alpha (WIPI49), a member of the novel 7-bladed WIPI protein family, is aberrantly expressed in human cancer and is linked to starvation-induced autophagy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156085

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

28 July 2018

1 reference

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Identification and characterization of murine SCD4, a novel heart-specific stearoyl-CoA desaturase isoform regulated by leptin and dietary factors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156085

Unsaturated fatty acids down-regulate srebp isoforms 1a and 1c by two mechanisms in HEK-293 cells

28 July 2018

1 reference

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Molecular mechanism of autophagy in yeast, Saccharomyces cerevisiae

28 July 2018

1 reference

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Tor, a phosphatidylinositol kinase homologue, controls autophagy in yeast

28 July 2018

1 reference

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3-Methyladenine: specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156085

ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156085

Dynamic and transient interactions of Atg9 with autophagosomes, but not membrane integration, are required for autophagy.

26 September 2018

1 reference

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Induction of autophagy by palmitic acid via protein kinase C-mediated signaling pathway independent of mTOR (mammalian target of rapamycin).

26 September 2018

1 reference

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Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy

26 September 2018

1 reference

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Decrease in membrane phospholipid unsaturation induces unfolded protein response

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156085

Shaping Development of Autophagy Inhibitors with the Structure of the Lipid Kinase Vps34

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156085

A combined proteomic and genetic analysis identifies a role for the lipid desaturase Desat1 in starvation-induced autophagy in Drosophila

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156085

Monitoring autophagic degradation of p62/SQSTM1.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156085

Kinase-inactivated ULK proteins inhibit autophagy via their conserved C-terminal domains using an Atg13-independent mechanism

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156085

FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156085

The Atg16L complex specifies the site of LC3 lipidation for membrane biogenesis in autophagy

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156085

Characterization of HSCD5, a novel human stearoyl-CoA desaturase unique to primates

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156085

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156085

Ultrastructural characterization of the delimiting membranes of isolated autophagosomes and amphisomes by freeze-fracture electron microscopy

26 September 2018

1 reference

12 December 2020

Freeze-fracture of drug-induced autophagocytosis in the mouse exocrine pancreas

1 reference

12 December 2020

Vinblastine-induced autophagic vacuoles in mouse liver and Ehrlich ascites tumor cells as assessed by freeze-fracture electron microscopy

1 reference

12 December 2020

Studies on vinblastine-induced autophagocytosis in mouse liver. V. A cytochemical study on the origin of membranes

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M114.591065

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25023287%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25023287%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

1 reference