The cynomolgus monkey (Macaca fascicularis) is the best animal model for the study of steroid glucuronidation (Q35207750)

7 August 2017

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title

The cynomolgus monkey (Macaca fascicularis) is the best animal model for the study of steroid glucuronidation (English)

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7 August 2017

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Olivier Barbier

1

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7 August 2017

Alain Bélanger

series ordinal

2

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7 August 2017

publication date

1 June 2003

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The Journal of Steroid Biochemistry and Molecular Biology

7 August 2017

published in

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7 August 2017

volume

85

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7 August 2017

issue

2-5

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7 August 2017

page(s)

235-245

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Pharmacogenomics: translating functional genomics into rational therapeutics

7 August 2017

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7 January 2021

The novel UGT1 gene complex links bilirubin, xenobiotics, and therapeutic drug metabolism by encoding UDP-glucuronosyltransferase isozymes with a common carboxyl terminus

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Identification of a genetic alteration in the code for bilirubin UDP-glucuronosyltransferase in the UGT1 gene complex of a Crigler-Najjar type I patient

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Expression of the UDP-glucuronosyltransferase 1A locus in human colon. Identification and characterization of the novel extrahepatic UGT1A8

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7 January 2021

Investigation of the substrate specificity of a cloned expressed human bilirubin UDP-glucuronosyltransferase: UDP-sugar specificity and involvement in steroid and xenobiotic glucuronidation

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Rat olfactory bulb and epithelium UDP-glucuronosyltransferase 2A1 (UGT2A1) expression: in situ mRNA localization and quantitative analysis

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7 January 2021

Odorant signal termination by olfactory UDP glucuronosyl transferase

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Glucuronidation of odorant molecules in the rat olfactory system: activity, expression and age-linked modifications of UDP-glucuronosyltransferase isoforms, UGT1A6 and UGT2A1, and relation to mitral cell activity

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7 January 2021

Isolation and characterization of a novel cDNA encoding a human UDP-glucuronosyltransferase active on C19 steroids

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7 January 2021

cDNA cloning and expression of two new members of the human liver UDP-glucuronosyltransferase 2B subfamily

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7 January 2021

Isolation and characterization of UGT2B15(Y85): a UDP-glucuronosyltransferase encoded by a polymorphic gene

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7 January 2021

Isolation and characterization of the UGT2B28 cDNA encoding a novel human steroid conjugating UDP-glucuronosyltransferase

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7 January 2021

Isolation and characterization of a human orphan UDP-glucuronosyltransferase, UGT2B11.

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7 January 2021

Isolation and characterization of the human UGT2B15 gene, localized within a cluster of UGT2B genes and pseudogenes on chromosome 4.

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7 January 2021

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7 January 2021

Isolation and characterization of the human UGT2B7 gene

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7 January 2021

Chromosomal localization, structure, and regulation of the UGT2B17 gene, encoding a C19 steroid metabolizing enzyme

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7 January 2021

Glucuronidation of arachidonic and linoleic acid metabolites by human UDP-glucuronosyltransferases

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7 January 2021

Plasma levels of C-19 steroids and 5 alpha-reduced steroid glucuronides in hyperandrogenic and idiopathic hirsute women.

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7 January 2021

Characterization of a cloned human dihydrotestosterone/androstanediol UDP-glucuronosyltransferase and its comparison to other steroid isoforms

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7 January 2021

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7 January 2021

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Levels of eighteen non-conjugated and conjugated steroids in human breast cyst fluid: relationships with cyst type

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7 January 2021

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7 January 2021

Isolation and characterization of the monkey UDP-glucuronosyltransferase cDNA clone monUGT1A01 active on bilirubin and estrogens

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7 January 2021

Effect of dioxin on ovarian function in the cynomolgus macaque (M. fascicularis).

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7 January 2021

Disposition of a low dose of bisphenol a in male and female cynomolgus monkeys

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7 January 2021

Metabolism of CP-195,543, a leukotriene B4 receptor antagonist, in the Long-Evans rat and Cynomolgus monkey

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7 January 2021

Pharmacokinetics of oral dehydroepiandrosterone (DHEA) in the ovariectomised cynomolgus monkey

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7 January 2021

Distribution of uridine diphosphate-glucuronosyltransferase (UGT) expression and activity in cynomolgus monkey tissues: evidence for differential expression of steroid-conjugating UGT enzymes in steroid target tissues

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

Expression and characterization of a novel UDP-glucuronosyltransferase, UGT2B9, from cynomolgus monkey

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7 January 2021

Molecular cloning, expression and characterization of a monkey steroid UDP-glucuronosyltransferase, UGT2B19, that conjugates testosterone

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7 January 2021

Isolation and characterization of the monkey UGT2B30 gene that encodes a uridine diphosphate-glucuronosyltransferase enzyme active on mineralocorticoid, glucocorticoid, androgen and oestrogen hormones

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7 January 2021

N-glycosylation and residue 96 are involved in the functional properties of UDP-glucuronosyltransferase enzymes

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7 January 2021

The effect of N-linked glycosylation on the substrate preferences of UDP glucuronosyltransferases

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7 January 2021

Cellular localization of uridine diphosphoglucuronosyltransferase 2B enzymes in the human prostate by in situ hybridization and immunohistochemistry

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7 January 2021

Drug-Responsive and Tissue-Specific Alternative Expression of Multiple First Exons in Rat UDP-Glucuronosyltransferase Family 1 (UGT1) Gene Complex

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7 January 2021

Molecular cloning of two cDNAs encoding the mouse bilirubin/phenol family of UDP-glucuronosyltransferases (mUGTBr/p).

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7 January 2021

Isolation and characterization of a UDP-glucuronosyltransferase (UGT1A01) cloned from female rhesus monkey

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7 January 2021

Follicular oestrogen synthesis: the 'two-cell, two-gonadotrophin' model revisited

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7 January 2021

Urinary tetrahydroaldosterone and aldosterone-18-glucuronide excretion in white and black normal subjects and hypertensive patients

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7 January 2021

Sodium transport-related proteins in the mammalian distal nephron - distribution, ontogeny and functional aspects

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7 January 2021

Differential regulation of two uridine diphospho-glucuronosyltransferases, UGT2B15 and UGT2B17, in human prostate LNCaP cells

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7 January 2021

Regulation of steroid glucuronosyltransferase activities and transcripts by androgen in the human prostatic cancer LNCaP cell line

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7 January 2021

FXR induces the UGT2B4 enzyme in hepatocytes: a potential mechanism of negative feedback control of FXR activity

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7 January 2021

The UDP-glucuronosyltransferase 1A9 enzyme is a peroxisome proliferator-activated receptor alpha and gamma target gene

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7 January 2021

Complexities of glucuronidation affecting in vitro in vivo extrapolation

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7 January 2021

10.1016/S0960-0760(03)00235-8

Identifiers

DOI

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7 August 2017

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