The development and regulation of gene repair (Q35209965)

7 August 2017

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title

The development and regulation of gene repair (English)

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7 August 2017

Li Liu

1

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PubMed ID

12951569

7 August 2017

Hetal Parekh-Olmedo

series ordinal

2

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PubMed ID

12951569

7 August 2017

Eric B Kmiec

series ordinal

3

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7 August 2017

1 September 2003

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7 August 2017

Nature Reviews Genetics

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7 August 2017

4

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7 August 2017

9

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7 August 2017

679-689

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https://scigraph.springernature.com/pub.10.1038/nrg1156

7 August 2017

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cites work

Progress and problems with the use of viral vectors for gene therapy

1 reference

Long-term survival of ex-thalassemic patients with persistent mixed chimerism after bone marrow transplantation

21 January 2018

1 reference

Mixed chimerism following in utero hematopoietic stem cell transplantation in murine models of hemoglobinopathy.

21 January 2018

1 reference

Manipulating the mammalian genome by homologous recombination

21 January 2018

1 reference

The DNA strand of chimeric RNA/DNA oligonucleotides can direct gene repair/conversion activity in mammalian and plant cell-free extracts

21 January 2018

1 reference

21 January 2018

1 reference

A role for RNA synthesis in homologous pairing events

21 January 2018

1 reference

RNA facilitates RecA-mediated DNA pairing and strand transfer between molecules bearing limited regions of homology

21 January 2018

1 reference

Targeted gene repair directed by the chimeric RNA/DNA oligonucleotide in a mammalian cell-free extract

21 January 2018

1 reference

Targeted gene correction by small single-stranded oligonucleotides in mammalian cells

21 January 2018

1 reference

Targeted single-base correction by RNA-DNA oligonucleotides

21 January 2018

1 reference

A sequence-specific gene correction by an RNA-DNA oligonucleotide in mammalian cells characterized by transfection and nuclear extract using a lacZ shuttle system

21 January 2018

1 reference

The synaptic complex of RecA protein participates in hybridization and inverse strand exchange reactions

21 January 2018

1 reference

In vivo gene repair of point and frameshift mutations directed by chimeric RNA/DNA oligonucleotides and modified single-stranded oligonucleotides

21 January 2018

1 reference

Rad51p and Rad54p, but not Rad52p, elevate gene repair in Saccharomyces cerevisiae directed by modified single-stranded oligonucleotide vectors

21 January 2018

1 reference

Strand bias in targeted gene repair is influenced by transcriptional activity

21 January 2018

1 reference

Mode of action of RNA/DNA oligonucleotides: progress in the development of gene repair as a therapy for alpha(1)-antitrypsin deficiency

21 January 2018

1 reference

Complement-stabilized D-loop. RecA-catalyzed stable pairing of linear DNA molecules at internal sites.

21 January 2018

1 reference

DNA hybrids stabilized by heterologies

21 January 2018

1 reference

Peptide nucleic acid (PNA) facilitates multistranded hybrid formation between linear double-stranded DNA targets and RecA protein-coated complementary single-stranded DNA probes

21 January 2018

1 reference

DNA pairing is an important step in the process of targeted nucleotide exchange

21 January 2018

1 reference

Opportunities and challenges in targeting genes for therapy

21 January 2018

1 reference

In vitro correction of cystic fibrosis epithelial cell lines by small fragment homologous replacement (SFHR) technique.

21 January 2018

1 reference

Harmful potential of viral vectors fuels doubts over gene therapy

21 January 2018

1 reference

Mechanisms underlying targeted gene correction using chimeric RNA/DNA and single-stranded DNA oligonucleotides

21 January 2018

1 reference

Optimising gene repair strategies in cell culture

21 January 2018

1 reference

Functional correction of episomal mutations with short DNA fragments and RNA-DNA oligonucleotides.

21 January 2018

1 reference

Gene targeting is enhanced in human cells overexpressing hRAD51.

21 January 2018

1 reference

Tailed duplex DNA is the preferred substrate for Rad51 protein-mediated homologous pairing

21 January 2018

1 reference

Transcription affects formation and processing of intermediates in oligonucleotide-mediated gene alteration

21 January 2018

1 reference

Mammalian DNA mismatch repair

21 January 2018

1 reference

Eukaryotic DNA mismatch repair

21 January 2018

1 reference

In vitro and in vivo nucleotide exchange directed by chimeric RNA/DNA oligonucleotides in Saccharomyces cerevisae

21 January 2018

1 reference

Damage recognition in nucleotide excision repair of DNA.

21 January 2018

1 reference

Nucleotide excision repair in mammalian cells

21 January 2018

1 reference

High efficiency mutagenesis, repair, and engineering of chromosomal DNA using single-stranded oligonucleotides

21 January 2018

1 reference

Targeted beta-globin gene conversion in human hematopoietic CD34(+ )and Lin(-)CD38(-)cells

21 January 2018

1 reference

Stable and inheritable changes in genotype and phenotype of albino melanocytes induced by an RNA-DNA oligonucleotide

21 January 2018

1 reference

Targeted gene correction of episomal DNA in mammalian cells mediated by a chimeric RNA.DNA oligonucleotide

21 January 2018

1 reference

Different frequency of gene targeting events by the RNA-DNA oligonucleotide among epithelial cells

21 January 2018

1 reference

Gene correction of the apolipoprotein (Apo) E2 phenotype to wild-type ApoE3 by in situ chimeraplasty

21 January 2018

1 reference

Chimeric RNA/DNA oligonucleotide-based gene therapy

21 January 2018

1 reference

Rescue of dystrophin expression in mdx mouse muscle by RNA/DNA oligonucleotides

21 January 2018

1 reference

Dystrophin gene repair in mdx muscle precursor cells in vitro and in vivo mediated by RNA-DNA chimeric oligonucleotides

21 January 2018

1 reference

Targeted correction of the point mutations of beta-thalassemia and targeted mutagenesis of the nucleotide associated with HPFH by RNA/DNA oligonucleotides: potential for beta-thalassemia gene therapy

21 January 2018

1 reference

Specific mismatch recognition in heteroduplex intermediates by p53 suggests a role in fidelity control of homologous recombination

21 January 2018

1 reference

Targeted correction of a defective selectable marker gene in human epithelial cells by small DNA fragments

21 January 2018

1 reference

Molecular dissection of interactions between Rad51 and members of the recombination-repair group

21 January 2018

1 reference

DNA pairing and strand exchange by the Escherichia coli RecA and yeast Rad51 proteins without ATP hydrolysis: on the importance of not getting stuck

21 January 2018

1 reference

Strand pairing by Rad54 and Rad51 is enhanced by chromatin

21 January 2018

1 reference

Overexpression of Rad51 protein stimulates homologous recombination and increases resistance of mammalian cells to ionizing radiation

21 January 2018

1 reference

Psoralens as photoactive probes of nucleic acid structure and function: organic chemistry, photochemistry, and biochemistry

21 January 2018

1 reference

Recombination induced by triple-helix-targeted DNA damage in mammalian cells

21 January 2018

1 reference

Triple helix directed psoralen adducts induce a low frequency of recombination in an SV40 shuttle vector

21 January 2018

1 reference

Short, single-stranded oligonucleotides mediate targeted nucleotide conversion using extracts from isolated liver mitochondria

21 January 2018

1 reference

Targeted gene modification in mismatch-repair-deficient embryonic stem cells by single-stranded DNA oligonucleotides

21 January 2018

1 reference

Re-engineering plant gene targeting

21 January 2018

1 reference

Mutations in yeast Rad51 that partially bypass the requirement for Rad55 and Rad57 in DNA repair by increasing the stability of Rad51-DNA complexes

21 January 2018

1 reference

Correction of the UDP-glucuronosyltransferase gene defect in the gunn rat model of crigler-najjar syndrome type I with a chimeric oligonucleotide

21 January 2018

1 reference

A plausible mechanism for gene correction by chimeric oligonucleotides

21 January 2018

1 reference

Mitochondria isolated from liver contain the essential factors required for RNA/DNA oligonucleotide-targeted gene repair

21 January 2018

1 reference

Chloroplast lysates support directed mutagenesis via modified DNA and chimeric RNA/DNA oligonucleotides

21 January 2018

1 reference

A tool for functional plant genomics: chimeric RNA/DNA oligonucleotides cause in vivo gene-specific mutations

21 January 2018

1 reference

Chimeric RNA/DNA Oligonucleotide-Based Site-Specific Modification of the Tobacco Acetolactate Syntase Gene

21 January 2018

1 reference

Targeted manipulation of maize genes in vivo using chimeric RNA/DNA oligonucleotides

21 January 2018

1 reference

Engineering herbicide-resistant maize using chimeric RNA/DNA oligonucleotides.

21 January 2018

1 reference

Genetic recombination of nucleosomal templates is mediated by transcription

21 January 2018

1 reference

DNA cruciforms facilitate in vitro strand transfer on nucleosomal templates.

31 March 2020

1 reference

Transformation of yeast with synthetic oligonucleotides

31 March 2020

1 reference

Transcription activates RecA-promoted homologous pairing of nucleosomal DNA.

31 March 2020

1 reference

Targeted nucleotide exchange in Saccharomyces cerevisiae directed by short oligonucleotides containing locked nucleic acids

31 March 2020

1 reference

In vivo and in vitro correction of the mdx dystrophin gene nonsense mutation by short-fragment homologous replacement

31 March 2020

1 reference

Influence of DNA delivery method on gene targeting frequencies in human cells

31 March 2020

1 reference

Rad54 protein is targeted to pairing loci by the Rad51 nucleoprotein filament

31 March 2020

1 reference

Human Rad51 protein promotes ATP-dependent homologous pairing and strand transfer reactions in vitro

31 March 2020

1 reference

DNA mismatch correction in a defined system

31 March 2020

1 reference

Correction of the mutation responsible for sickle cell anemia by an RNA-DNA oligonucleotide

31 March 2020

1 reference

Targeted gene conversion in a mammalian CD34+-enriched cell population using a chimeric RNA/DNA oligonucleotide

31 March 2020

1 reference

Localized in vivo genotypic and phenotypic correction of the albino mutation in skin by RNA-DNA oligonucleotide

31 March 2020

1 reference

Targeted nucleotide exchange in the alkaline phosphatase gene of HuH-7 cells mediated by a chimeric RNA/DNA oligonucleotide

31 March 2020

1 reference

In vivo site-directed mutagenesis of the factor IX gene by chimeric RNA/DNA oligonucleotides

31 March 2020

1 reference

Nucleotide exchange in genomic DNA of rat hepatocytes using RNA/DNA oligonucleotides. Targeted delivery of liposomes and polyethyleneimine to the asialoglycoprotein receptor

31 March 2020

1 reference

Homologous recombination based gene therapy

31 March 2020

1 reference

In vivo targeted repair of a point mutation in the canine dystrophin gene by a chimeric RNA/DNA oligonucleotide

31 March 2020

1 reference

Persistent failures in gene repair

31 March 2020

1 reference

Recombinant DNA technique and sickle cell anemia research

31 March 2020

1 reference

31 March 2020

Gene repair validation

1 reference

Enhanced gene transfer into HuH-7 cells and primary rat hepatocytes using targeted liposomes and polyethylenimine

31 March 2020

1 reference

Analysis of the binding of p53 to DNAs containing mismatched and bulged bases

31 March 2020

1 reference

Cloning of large segments of exogenous DNA into yeast by means of artificial chromosome vectors

31 March 2020

1 reference

High-affinity triple helix formation by synthetic oligonucleotides at a site within a selectable mammalian gene.

31 March 2020

1 reference

High-efficiency triple-helix-mediated photo-cross-linking at a targeted site within a selectable mammalian gene

31 March 2020

1 reference

The many faces of chromatin remodeling: SWItching beyond transcription

31 March 2020

1 reference

Correction/mutation of acid α-D-glucosidase gene by modified single-stranded oligonucleotides: in vitro and in vivo studies

31 March 2020

1 reference

Genetic repair of mutations in plant cell-free extracts directed by specific chimeric oligonucleotides

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRG1156

1 reference

7 August 2017

1 reference

PubMed ID

12951569