Advancing age increases sperm chromatin damage and impairs fertility in peroxiredoxin 6 null mice. (Q35211462)

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3 March 2020

title

Advancing age increases sperm chromatin damage and impairs fertility in peroxiredoxin 6 null mice (English)

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3 March 2020

1

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3 March 2020

author name string

Sheldon I Feinstein

series ordinal

2

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3 March 2020

Aron B Fisher

series ordinal

3

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3 March 2020

Cristian O'Flaherty

series ordinal

4

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publication date

25 February 2015

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3 March 2020

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3 March 2020

volume

5

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3 March 2020

page(s)

15-23

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Oxidative stress impairs function and increases redox protein modifications in human spermatozoa

3 March 2020

cites work

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Aging results in differential regulation of DNA repair pathways in pachytene spermatocytes in the Brown Norway rat

13 July 2018

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13 July 2018

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A genome-wide chromatin-associated nuclear peroxiredoxin from the malaria parasite Plasmodium falciparum

13 July 2018

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Are sperm chromatin and DNA defects relevant in the clinic?

13 July 2018

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Advancing paternal age and risk of autism: new evidence from a population-based study and a meta-analysis of epidemiological studies

13 July 2018

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Peroxiredoxin 6: A Bifunctional Enzyme with Glutathione Peroxidase and Phospholipase A2Activities

13 July 2018

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Hydrogen peroxide modifies human sperm peroxiredoxins in a dose-dependent manner

13 July 2018

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Comparison of glutathione peroxidase 1 and peroxiredoxin 6 in protection against oxidative stress in the mouse lung

13 July 2018

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Paternal factors and low birthweight, preterm, and small for gestational age births: a systematic review

13 July 2018

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Mitochondrial glutathione peroxidase 4 disruption causes male infertility

13 July 2018

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Advancing Paternal Age and Bipolar Disorder

13 July 2018

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Diabetes and the impairment of reproductive function: possible role of mitochondria and reactive oxygen species.

13 July 2018

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Disruption of maternal DNA repair increases sperm-derived chromosomal aberrations

13 July 2018

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The effects of age on DNA fragmentation, chromatin packaging and conventional semen parameters in spermatozoa of oligoasthenoteratozoospermic patients

13 July 2018

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Spermatozoa have decreased antioxidant enzymatic capacity and increased reactive oxygen species production during aging in the Brown Norway rat

13 July 2018

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Advancing age has differential effects on DNA damage, chromatin integrity, gene mutations, and aneuploidies in sperm.

13 July 2018

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Fertility rates and future population trends: will Europe's birth rate recover or continue to decline?

13 July 2018

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Peroxiredoxins: a historical overview and speculative preview of novel mechanisms and emerging concepts in cell signaling

13 July 2018

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Paternal age and schizophrenia: a population based cohort study

13 July 2018

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Activation of the antioxidant enzyme 1-CYS peroxiredoxin requires glutathionylation mediated by heterodimerization with pi GST.

13 July 2018

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Effects of age on DNA double-strand breaks and apoptosis in human sperm

13 July 2018

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1-Cys peroxiredoxin knock-out mice express mRNA but not protein for a highly related intronless gene

13 July 2018

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1-Cys peroxiredoxin overexpression protects cells against phospholipid peroxidation-mediated membrane damage

13 July 2018

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Male fertility is linked to the selenoprotein phospholipid hydroperoxide glutathione peroxidase

13 July 2018

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Base excision repair is limited by different proteins in male germ cell nuclear extracts prepared from young and old mice

13 July 2018

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Sperm chromatin structure assay: its clinical use for detecting sperm DNA fragmentation in male infertility and comparisons with other techniques

13 July 2018

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Identification of a specific sperm nuclei selenoenzyme necessary for protamine thiol cross-linking during sperm maturation

13 July 2018

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Effects of male age on semen quality and fertility: a review of the literature

13 July 2018

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Aneuploidy in human sperm: a review of the frequency and distribution of aneuploidy, effects of donor age and lifestyle factors

13 July 2018

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Dual function of the selenoprotein PHGPx during sperm maturation

13 July 2018

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Phospholipid hydroperoxides are substrates for non-selenium glutathione peroxidase

13 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371547

Mutation frequency declines during spermatogenesis in young mice but increases in old mice

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371547

Effects of heat stress on mouse testicular cells and sperm chromatin structure.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371547

Ultrastructural abnormalities of human spermatozoa

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371547

The senescence-accelerated mouse prone 8 as a model for oxidative stress and impaired DNA repair in the male germ line.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371547

The presence of a truncated base excision repair pathway in human spermatozoa that is mediated by OGG1.

26 September 2018

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Incomplete protection of genetic integrity of mature spermatozoa against oxidative stress

26 September 2018

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Paternal age and sperm DNA decay: discrepancy between chromomycin and aniline blue staining

26 September 2018

1 reference

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Frequency of human sperm carrying structural aberrations of chromosome 1 increases with advancing age.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371547

Changes in spermatozoal chromatin packaging and susceptibility to oxidative challenge during aging

26 September 2018

1 reference

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The nuclear form of phospholipid hydroperoxide glutathione peroxidase is a protein thiol peroxidase contributing to sperm chromatin stability.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371547

Effect of glutathione depletion on antioxidant enzymes in the epididymis, seminal vesicles, and liver and on spermatozoa motility in the aging brown Norway rat.

26 September 2018

1 reference

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Comparison of semen quality in older and younger men attending an andrology clinic

26 September 2018

1 reference

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The role of DNA strand breaks in human spermatozoa used for IVF and ICSI.

26 September 2018

1 reference

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Fertilizing ability of DNA-damaged spermatozoa

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371547

Paternal age affects fertility and progeny outcome in the Brown Norway rat

26 September 2018

1 reference

12 December 2020

Impact of chemotherapeutics and advanced testicular cancer or Hodgkin lymphoma on sperm deoxyribonucleic acid integrity

1 reference

12 December 2020

Aneuploidies and micronuclei in the germ cells of male mice of advanced age

1 reference

12 December 2020

Linear increase of structural and numerical chromosome 9 abnormalities in human sperm regarding age

1 reference

12 December 2020

Characterization of sperm chromatin quality in testicular cancer and Hodgkin's lymphoma patients prior to chemotherapy

1 reference

12 December 2020

Sperm chromatin structure assay parameters measured after density gradient centrifugation are not predictive for the outcome of ART

1 reference

12 December 2020

GC-->CG transversion mutation might be caused by 8-oxoguanine oxidation product

1 reference

12 December 2020

Oxidative stress in testis of animals during aging with and without reproductive activity

1 reference

12 December 2020

Sperm structural and motility changes during aging in the Brown Norway rat

1 reference

12 December 2020

Low amounts and high thiol oxidation of peroxiredoxins in spermatozoa from infertile men

1 reference

12 December 2020

10.1016/J.REDOX.2015.02.004

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25796034%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25796034%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

PubMed publication ID

25796034

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25796034%20AND%20SRC:MED&resulttype=core&format=json