A dynamic T cell-limited checkpoint regulates affinity-dependent B cell entry into the germinal center (Q35213561)

7 August 2017

A dynamic T cell-limited checkpoint regulates affinity-dependent B cell entry into the germinal center (English)

1 reference

7 August 2017

Monica R Mugnier

5

0 references

Gabriel Victora

Gabriel D Victora

2

0 references

Michael L Dustin

Michael L Dustin

7

0 references

Michel C. Nussenzweig

8

Michel C Nussenzweig

1 reference

7 August 2017

Tanja A Schwickert

1

0 references

Alice O Kamphorst

4

Alice O Kamphorst

1 reference

7 August 2017

David R Fooksman

3

1 reference

PubMed ID

21576382

7 August 2017

Alexander D Gitlin

6

1 reference

PubMed ID

21576382

7 August 2017

language of work or name

English

0 references

publication date

16 May 2011

1 reference

Journal of Experimental Medicine

7 August 2017

1 reference

7 August 2017

208

1 reference

7 August 2017

1243-1252

1 reference

7 August 2017

6

1 reference

Germinal center dynamics revealed by multiphoton microscopy with a photoactivatable fluorescent reporter

7 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173244

Polyreactivity increases the apparent affinity of anti-HIV antibodies by heteroligation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173244

Inhibition of follicular T-helper cells by CD8(+) regulatory T cells is essential for self tolerance.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173244

H2-O, a MHC class II-like protein, sets a threshold for B-cell entry into germinal centers

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173244

Route of antigen uptake differentially impacts presentation by dendritic cells and activated monocytes

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173244

Finding the right niche: B-cell migration in the early phases of T-dependent antibody responses

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173244

Capture of influenza by medullary dendritic cells via SIGN-R1 is essential for humoral immunity in draining lymph nodes

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173244

Functional anatomy of T cell activation and synapse formation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173244

AID produces DNA double-strand breaks in non-Ig genes and mature B cell lymphomas with reciprocal chromosome translocations

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173244

Germinal center reutilization by newly activated B cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173244

Visualizing B cell capture of cognate antigen from follicular dendritic cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173244

Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173244

Antibody recognition of a highly conserved influenza virus epitope

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173244

AID is required for the chromosomal breaks in c-myc that lead to c-myc/IgH translocations

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173244

SAP-controlled T-B cell interactions underlie germinal centre formation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173244

T follicular helper (TFH) cells in normal and dysregulated immune responses

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173244

Subcapsular sinus macrophages in lymph nodes clear lymph-borne viruses and present them to antiviral B cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173244

In vivo imaging of germinal centres reveals a dynamic open structure

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173244

Antigen recognition strength regulates the choice between extrafollicular plasma cell and germinal center B cell differentiation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173244

Antigen targeting to dendritic cells elicits long-lived T cell help for antibody responses

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173244

A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173244

Antigen-engaged B cells undergo chemotaxis toward the T zone and form motile conjugates with helper T cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173244

Mouse in red: red fluorescent protein expression in mouse ES cells, embryos, and adult animals.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173244

Visualizing dendritic cell networks in vivo

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173244

Efficient targeting of protein antigen to the dendritic cell receptor DEC-205 in the steady state leads to antigen presentation on major histocompatibility complex class I products and peripheral CD8+ T cell tolerance

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173244

Embryonic stem cells and mice expressing different GFP variants for multiple non-invasive reporter usage within a single animal

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173244

Very low affinity B cells form germinal centers, become memory B cells, and participate in secondary immune responses when higher affinity competition is reduced

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173244

Balanced responsiveness to chemoattractants from adjacent zones determines B-cell position

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173244

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173244

A monoclonal antibody to the DEC-205 endocytosis receptor on human dendritic cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173244

BCL-6 mutations in normal germinal center B cells: evidence of somatic hypermutation acting outside Ig loci

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173244

Visualization of specific B and T lymphocyte interactions in the lymph node.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173244

Clonal selection and learning in the antibody system

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173244

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173244

The receptor DEC-205 expressed by dendritic cells and thymic epithelial cells is involved in antigen processing

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173244

Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173244

Antibody engineering for the analysis of affinity maturation of an anti-hapten response.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173244

In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. I. The architecture and dynamics of responding cell populations

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173244

Sites of specific B cell activation in primary and secondary responses to T cell-dependent and T cell-independent antigens

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173244

Initial clonal expansion of germinal center B cells takes place at the perimeter of follicles

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173244

Subcapsular encounter and complement-dependent transport of immune complexes by lymph node B cells.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173244

The humoral immune response is initiated in lymph nodes by B cells that acquire soluble antigen directly in the follicles.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173244

Imaging of germinal center selection events during affinity maturation

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173244

Role of antigen receptor affinity in T cell-independent antibody responses in vivo

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173244

Mutation of BCL-6 gene in normal B cells by the process of somatic hypermutation of Ig genes.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173244

Germinal centers develop oligoclonally

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173244

Defective TCR expression in transgenic mice constructed using cDNA-based α- and β-chain genes under the control of heterologous regulatory elements

26 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1084%2FJEM.20102477

Observation of Antigen-Dependent CD8+ T-Cell/ Dendritic Cell Interactions in Vivo

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1084%2FJEM.20102477

On the complexity of self

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1084%2FJEM.20102477

Extrafollicular activation of lymph node B cells by antigen-bearing dendritic cells

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21576382

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

B cells acquire particulate antigen in a macrophage-rich area at the boundary between the follicle and the subcapsular sinus of the lymph node

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21576382

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Role of BCR affinity in T cell dependent antibody responses in vivo

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21576382

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1084/JEM.20102477

1 reference

7 August 2017

1 reference

7 August 2017

1 reference

PubMed ID

21576382