Anandamide inhibits Theiler's virus induced VCAM-1 in brain endothelial cells and reduces leukocyte transmigration in a model of blood brain barrier by activation of CB(1) receptors (Q35213727)

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English	Anandamide inhibits Theiler's virus induced VCAM-1 in brain endothelial cells and reduces leukocyte transmigration in a model of blood brain barrier by activation of CB(1) receptors	scientific article

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scholarly article

1 reference

Europe PubMed Central

7 August 2017

Anandamide inhibits Theiler's virus induced VCAM-1 in brain endothelial cells and reduces leukocyte transmigration in a model of blood brain barrier by activation of CB(1) receptors (English)

1 reference

Europe PubMed Central

7 August 2017

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blood–brain barrier

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based on heuristic

inferred from title

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ORCID Public Data File 2021

author name string

Leyre Mestre

1

1 reference

Europe PubMed Central

7 August 2017

Paula M Iñigo

2

1 reference

Europe PubMed Central

7 August 2017

Miriam Mecha

3

1 reference

Europe PubMed Central

7 August 2017

Fernando G Correa

4

1 reference

Europe PubMed Central

7 August 2017

Miriam Hernangómez-Herrero

5

1 reference

Europe PubMed Central

7 August 2017

Frida Loría

6

1 reference

Europe PubMed Central

7 August 2017

Fabian Docagne

7

1 reference

Europe PubMed Central

7 August 2017

José Borrell

8

1 reference

Europe PubMed Central

7 August 2017

Carmen Guaza

9

1 reference

Europe PubMed Central

7 August 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

18 August 2011

1 reference

Europe PubMed Central

7 August 2017

Journal of Neuroinflammation

1 reference

Europe PubMed Central

7 August 2017

8

1 reference

Europe PubMed Central

7 August 2017

102

1 reference

Europe PubMed Central

7 August 2017

https://scigraph.springernature.com/pub.10.1186/1742-2094-8-102

0 references

Review: leucocyte-endothelial cell crosstalk at the blood-brain barrier: a prerequisite for successful immune cell entry to the brain

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The endocannabinoid system as a target for the treatment of neurodegenerative disease

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Mending the broken brain: neuroimmune interactions in neurogenesis

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The endocannabinoid system in the inflammatory and neurodegenerative processes of multiple sclerosis and of amyotrophic lateral sclerosis.

1 reference

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13 July 2018

Modulation of the endocannabinoid system: neuroprotection or neurotoxicity?

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The innate immune response affects the development of the autoimmune response in Theiler's virus-induced demyelinating disease

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Emerging strategies for exploiting cannabinoid receptor agonists as medicines

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CNS immune surveillance and neuroinflammation: endocannabinoids keep control.

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Differential virus replication, cytokine production, and antigen-presenting function by microglia from susceptible and resistant mice infected with Theiler's virus

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COX-2, CB2 and P2X7-immunoreactivities are increased in activated microglial cells/macrophages of multiple sclerosis and amyotrophic lateral sclerosis spinal cord

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The endocannabinoid 2-AG protects the blood-brain barrier after closed head injury and inhibits mRNA expression of proinflammatory cytokines

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Evaluation of the immortalised mouse brain capillary endothelial cell line, b.End3, as an in vitro blood-brain barrier model for drug uptake and transport studies

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Chemokine-dependent mechanisms of leukocyte trafficking across a model of the blood–brain barrier

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Establishment and functional characterization of an in vitro model of the blood-brain barrier, comprising a co-culture of brain capillary endothelial cells and astrocytes.

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21 January 2018

Cannabinoid-mediated neuroprotection, not immunosuppression, may be more relevant to multiple sclerosis

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Characteristics of cloned cerebrovascular endothelial cells following infection with Theiler's virus. II. Persistent infection

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Anti-adhesion molecule therapy in Theiler's murine encephalomyelitis virus-induced demyelinating disease

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The synthetic cannabinoid WIN 55,212-2 increases COX-2 expression and PGE2 release in murine brain-derived endothelial cells following Theiler's virus infection

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Endothelial cells from diverse tissues exhibit differences in growth and morphology.

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Induction of cyclooxygenase-2 by anandamide in cerebral microvascular endothelium

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Endothelin-1 increases 2-arachidonoyl glycerol (2-AG) production in astrocytes

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The endogenous cannabinoid anandamide potentiates interleukin-6 production by astrocytes infected with Theiler's murine encephalomyelitis virus by a receptor-mediated pathway

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The endocannabinoid anandamide downregulates IL-23 and IL-12 subunits in a viral model of multiple sclerosis: evidence for a cross-talk between IL-12p70/IL-23 axis and IL-10 in microglial cells.

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26 September 2018

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26 September 2018

Therapeutic action of cannabinoids in a murine model of multiple sclerosis.

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Natalizumab treatment reduces endothelial activity in MS patients

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https://pubmed.ncbi.nlm.nih.gov/21851608

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Regulation by cannabinoid receptors of anandamide transport across the blood-brain barrier and through other endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21851608

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Endocannabinoids and traumatic brain injury

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https://pubmed.ncbi.nlm.nih.gov/21851608

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The cannabinoid receptor 1 gene (CNR1) and multiple sclerosis: an association study in two case-control groups from Spain

1 reference

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The (AAT)n repeat of the cannabinoid CB1 receptor gene influences disease progression in relapsing multiple sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21851608

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12 December 2020

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10.1186/1742-2094-8-102

1 reference

Europe PubMed Central

7 August 2017

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1 reference

Europe PubMed Central

7 August 2017

1 reference

Europe PubMed Central

7 August 2017

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