Phase I randomized, double-blind pilot study of micronized resveratrol (SRT501) in patients with hepatic metastases--safety, pharmacokinetics, and pharmacodynamics (Q35215147)

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English	Phase I randomized, double-blind pilot study of micronized resveratrol (SRT501) in patients with hepatic metastases--safety, pharmacokinetics, and pharmacodynamics	scientific article

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scholarly article

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5 February 2020

Phase I randomized, double-blind pilot study of micronized resveratrol (SRT501) in patients with hepatic metastases--safety, pharmacokinetics, and pharmacodynamics (English)

1 reference

Europe PubMed Central

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5 February 2020

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based on heuristic

inferred from title

pharmacokinetics

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based on heuristic

inferred from title

pharmacodynamics

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based on heuristic

inferred from title

7

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5 February 2020

author name string

Lynne M Howells

1

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5 February 2020

D P Berry

2

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P J Elliott

3

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E W Jacobson

4

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E Hoffmann

5

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B Hegarty

6

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W P Steward

8

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A J Gescher

9

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publication date

16 June 2011

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5 February 2020

Cancer Prevention Research

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4

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1419-1425

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9

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5 February 2020

Repeat dose study of the cancer chemopreventive agent resveratrol in healthy volunteers: safety, pharmacokinetics, and effect on the insulin-like growth factor axis

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28 July 2018

Clinical pharmacology of resveratrol and its metabolites in colorectal cancer patients.

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28 July 2018

Resveratrol in the chemoprevention and treatment of hepatocellular carcinoma

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28 July 2018

Cancer prevention and treatment with resveratrol: from rodent studies to clinical trials

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28 July 2018

A low dose of dietary resveratrol partially mimics caloric restriction and retards aging parameters in mice

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28 July 2018

Low concentrations of resveratrol inhibit Wnt signal throughput in colon-derived cells: implications for colon cancer prevention

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Sirtuins: novel targets for metabolic disease.

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28 July 2018

Phase I dose escalation pharmacokinetic study in healthy volunteers of resveratrol, a potential cancer chemopreventive agent

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28 July 2018

Resveratrol: a review of preclinical studies for human cancer prevention

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28 July 2018

Therapeutic potential of resveratrol: the in vivo evidence

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28 July 2018

Role of resveratrol in prevention and therapy of cancer: preclinical and clinical studies.

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28 July 2018

High absorption but very low bioavailability of oral resveratrol in humans

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28 July 2018

Pharmacokinetics in mice and growth-inhibitory properties of the putative cancer chemopreventive agent resveratrol and the synthetic analogue trans 3,4,5,4'-tetramethoxystilbene.

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28 July 2018

Cancer chemoprevention by resveratrol: in vitro and in vivo studies and the underlying mechanisms (review).

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28 July 2018

Resveratrol induces growth inhibition, S-phase arrest, apoptosis, and changes in biomarker expression in several human cancer cell lines.

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28 July 2018

Resveratrol-induced activation of p53 and apoptosis is mediated by extracellular-signal-regulated protein kinases and p38 kinase

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28 July 2018

Steady-State pharmacokinetics and tolerability of trans-resveratrol 2000 mg twice daily with food, quercetin and alcohol (ethanol) in healthy human subjects.

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26 September 2018

Pharmacokinetics of trans-resveratrol following repeated administration in healthy elderly and young subjects

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26 September 2018

Pharmacokinetic and safety profile of trans-resveratrol in a rising multiple-dose study in healthy volunteers

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26 September 2018

Resveratrol-mediated chemoprevention of diethylnitrosamine-initiated hepatocarcinogenesis: inhibition of cell proliferation and induction of apoptosis

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26 September 2018

Chemoprevention by resveratrol: molecular mechanisms and therapeutic potential

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26 September 2018

Resveratrol-induced apoptosis is associated with Fas redistribution in the rafts and the formation of a death-inducing signaling complex in colon cancer cells

1 reference

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26 September 2018

Distribution of [14C]-trans-resveratrol, a cancer chemopreventive polyphenol, in mouse tissues after oral administration

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Identifiers

10.1158/1940-6207.CAPR-11-0148

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Europe PubMed Central

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5 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21680702%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21680702%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

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