Th1 cytokine-secreting recombinant Mycobacterium bovis bacillus Calmette-Guérin and prospective use in immunotherapy of bladder cancer. (Q35215350)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21941579%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

review article

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12 September 2020

Th1 cytokine-secreting recombinant Mycobacterium bovis bacillus Calmette-Guérin and prospective use in immunotherapy of bladder cancer (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21941579%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

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20 November 2019

29 May 2020

12 September 2020

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12 September 2020

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12 October 2019

hemic and immune systems

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18 October 2019

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20 November 2019

1 reference

Mycobacterium bovis

1 reference

1

1 reference

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13 February 2020

M A O'Donnell

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3

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13 February 2020

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Jonathan Henning

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15 September 2011

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13 February 2020

29 May 2020

12 September 2020

Clinical and Developmental Immunology

10 references

3 April 2019

22 April 2019

20 June 2019

3 August 2019

9 August 2019

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18 October 2019

20 November 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21941579%20AND%20SRC:MED&resulttype=core&format=json

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2011

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13 February 2020

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Creative Commons Attribution 3.0 Unported

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Thirty years of BCG immunotherapy for non-muscle invasive bladder cancer: a success story with room for improvement.

28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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Fibronectin-mediated Calmette-Guerin bacillus attachment to murine bladder mucosa. Requirement for the expression of an antitumor response

28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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Presence of activated lymphocytes in the urine of patients with superficial bladder cancer after intravesical immunotherapy with bacillus Calmette-Guérin

28 July 2018

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An investigation of factors influencing the in vitro induction of LAK activity against a variety of human bladder cancer cell lines

28 July 2018

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28 July 2018

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Expression of Escherichia coli beta-galactosidase in Mycobacterium bovis BCG using an expression system isolated from Mycobacterium paratuberculosis which induced humoral and cellular immune responses

28 July 2018

1 reference

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Bacillus Calmette-Guérin with or without interferon α-2b and megadose versus recommended daily allowance vitamins during induction and maintenance intravesical treatment of nonmuscle invasive bladder cancer.

28 July 2018

1 reference

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Recent advances in bacillus Calmette-Guerin immunotherapy in bladder cancer.

26 September 2018

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Intravesical immunotherapy of superficial bladder cancer with chitosan/interleukin-12.

26 September 2018

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p21 Expression by human urothelial carcinoma cells modulates the phenotypic response to BCG.

26 September 2018

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A possible mechanism of intravesical BCG therapy for human bladder carcinoma: involvement of innate effector cells for the inhibition of tumor growth

26 September 2018

1 reference

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Role of neutrophils in BCG immunotherapy for bladder cancer

26 September 2018

1 reference

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Efficacy of recombinant bacille Calmette-Guérin vaccine secreting interleukin-15/antigen 85B fusion protein in providing protection against Mycobacterium tuberculosis.

26 September 2018

1 reference

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Recombinant BCG coexpressing Ag85B, ESAT-6 and mouse-IFN-gamma confers effective protection against Mycobacterium tuberculosis in C57BL/6 mice.

26 September 2018

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Internalization of Mycobacterium bovis, Bacillus Calmette Guerin, by bladder cancer cells is cytotoxic

26 September 2018

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Discriminators of mouse bladder response to intravesical Bacillus Calmette-Guerin (BCG).

26 September 2018

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Bacillus Calmette-Guérin induces p21 expression in human transitional carcinoma cell lines via an immediate early, p53 independent pathway

26 September 2018

1 reference

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Neutrophil granulocytes are required for effective Bacillus Calmette-Guérin immunotherapy of bladder cancer and orchestrate local immune responses.

26 September 2018

1 reference

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Cytokine-modified Mycobacterium smegmatis as a novel anticancer immunotherapy.

26 September 2018

1 reference

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Tumor necrosis factor-related apoptosis-inducing ligand: a novel mechanism for Bacillus Calmette-Guérin-induced antitumor activity.

26 September 2018

1 reference

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Prolonged antigen presentation, APC-, and CD8+ T cell turnover during mycobacterial infection: comparison with Listeria monocytogenes.

26 September 2018

1 reference

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The immunomodulating effect of interferon-gamma intravesical instillations in preventing bladder cancer recurrence.

26 September 2018

1 reference

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Interleukin 10 induced augmentation of delayed-type hypersensitivity (DTH) enhances Mycobacterium bovis bacillus Calmette-Guérin (BCG) mediated antitumour activity.

26 September 2018

1 reference

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Induction of MUC1-specific cellular immunity by a recombinant BCG expressing human MUC1 and secreting IL2.

26 September 2018

1 reference

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Immunization with type 5 adenovirus recombinant for a tumor antigen in combination with recombinant canarypox virus (ALVAC) cytokine gene delivery induces destruction of established prostate tumors

26 September 2018

1 reference

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Prognostic value of a T helper 1 urinary cytokine response after intravesical bacillus Calmette-Guerin treatment for superficial bladder cancer

26 September 2018

1 reference

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Co-expression of interleukin-2 and green fluorescent protein reporter in mycobacteria: in vivo application for monitoring antimycobacterial immunity.

26 September 2018

1 reference

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Perforin-mediated lysis of tumor cells by Mycobacterium bovis Bacillus Calmette-Guérin-activated killer cells.

26 September 2018

1 reference

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Aerosol infection of mice with recombinant BCG secreting murine IFN-gamma partially reconstitutes local protective immunity.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173967

Maintenance bacillus Calmette-Guerin immunotherapy for recurrent TA, T1 and carcinoma in situ transitional cell carcinoma of the bladder: a randomized Southwest Oncology Group Study

26 September 2018

1 reference

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Bacille Calmette-Guérin (BCG)-associated inflammation and fibrosis: modulation by recombinant BCG expressing interferon-gamma (IFN-gamma).

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173967

Urinary cytokines during intravesical bacillus Calmette-Guerin therapy for superficial bladder cancer: processing, stability and prognostic value

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173967

Protective humoral response against pneumococcal infection in mice elicited by recombinant bacille Calmette-Guérin vaccines expressing pneumococcal surface protein A.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173967

Bacillus Calmette-Guerin (BCG) enhances monocyte- and lymphocyte-mediated bladder tumour cell killing.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173967

Humoral and cell-mediated immune responses to live recombinant BCG–HIV vaccines

26 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1155%2F2011%2F728930

Systemic and mucosal immunity induced by BCG vector expressing outer-surface protein A of Borrelia burgdorferi

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1155%2F2011%2F728930

Role of Th1-stimulating cytokines in bacillus Calmette-Guérin (BCG)-induced macrophage cytotoxicity against mouse bladder cancer MBT-2 cells

21 January 2018

1 reference

12 December 2020

Immunological properties of recombinant Mycobacterium bovis bacillus Calmette-Guérin strain expressing fusion protein IL-2-ESAT-6

1 reference

12 December 2020

Mycobacterium bovis bacillus Calmette-Guérin (BCG) induces human CC- and CXC-chemokines in vitro and in vivo

1 reference

12 December 2020

Dose-dependent synergy of Th1-stimulating cytokines on bacille Calmette-Guérin-induced interferon-gamma production by human mononuclear cells

1 reference

12 December 2020

Cutting edge: major CD8 T cell response to live bacillus Calmette-Guérin is mediated by CD1 molecules

1 reference

12 December 2020

Improved protection against disseminated tuberculosis by Mycobacterium bovis bacillus Calmette-Guerin secreting murine GM-CSF is associated with expansion and activation of APCs

1 reference

12 December 2020

Murine IL-2 secreting recombinant Bacillus Calmette-Guerin augments macrophage-mediated cytotoxicity against murine bladder cancer MBT-2

1 reference

12 December 2020

In vitro generation of bacillus Calmette-Guérin-activated killer cells

1 reference

12 December 2020

Recombinant bacille Calmette-Guérin (BCG) expressing human interferon-alpha 2B demonstrates enhanced immunogenicity

1 reference

12 December 2020

NK cells are essential for effective BCG immunotherapy

1 reference

12 December 2020

Salvage intravesical therapy with interferon-alpha 2b plus low dose bacillus Calmette-Guerin is effective in patients with superficial bladder cancer in whom bacillus Calmette-Guerin alone previously failed

1 reference

12 December 2020

IFN-gamma and IL-12 but not IL-10 are required for local tumour surveillance in a syngeneic model of orthotopic bladder cancer

1 reference

12 December 2020

Surface antigen expression on bladder tumor cells induced by bacillus Calmette-Guérin (BCG): A role of BCG internalization into tumor cells

1 reference

12 December 2020

Manipulation of immune responses to Mycobacterium bovis by vaccination with IL-2- and IL-18-secreting recombinant bacillus Calmette Guerin

1 reference

12 December 2020

IL-2-secreting recombinant bacillus Calmette Guerin can overcome a Type 2 immune response and corticosteroid-induced immunosuppression to elicit a Type 1 immune response

1 reference

12 December 2020

Interleukin-6 production by human bladder tumor cell lines is up-regulated by bacillus Calmette-Guérin through nuclear factor-kappaB and Ap-1 via an immediate early pathway

1 reference

12 December 2020

Intravesical instillations of interferon gamma in the prophylaxis of high risk superficial bladder cancer--results of a controlled prospective study

1 reference

12 December 2020

Lymphocyte activation by granulocyte macrophage-colony stimulating factor in human bladder cancer

1 reference

12 December 2020

Development and preclinical evaluation of a Bacillus Calmette-Guérin-MUC1-based novel breast cancer vaccine

1 reference

12 December 2020

Phase 1 study of the intravesical administration of recombinant human interleukin-12 in patients with recurrent superficial transitional cell carcinoma of the bladder

1 reference

12 December 2020

TLR2 and TLR4 serve distinct roles in the host immune response against Mycobacterium bovis BCG

1 reference

12 December 2020

Bacillus Calmete-Guérin plus interferon-alpha2B intravesical therapy maintains an extended treatment plan for superficial bladder cancer with minimal toxicity

1 reference

12 December 2020

Intracavitary Bacillus Calmette-Guerin in the treatment of superficial bladder tumors

1 reference

12 December 2020

Intravesical therapy for bladder cancer

1 reference

12 December 2020

Novel recombinant BCG coexpressing Ag85B, ESAT-6 and mouse TNF-alpha induces significantly enhanced cellular immune and antibody responses in C57BL/6 mice

1 reference

12 December 2020

Co-administration of intravesical bacillus Calmette-Guérin and interferon α-2B as first line in treating superficial transitional cell carcinoma of the urinary bladder

1 reference

12 December 2020

Effects of local bacillus Calmette-Guerin therapy in patients with bladder carcinoma on immunocompetent cells of the bladder wall

1 reference

12 December 2020

Elevations of cytokines interleukin-1, interleukin-2 and tumor necrosis factor in the urine of patients after intravesical bacillus Calmette-Guerin immunotherapy

1 reference

12 December 2020

Leukocytes in the urine after intravesical BCG treatment for superficial bladder cancer. A flow cytofluorometric analysis

1 reference

12 December 2020

Leukocytes and cytokines in the urine of superficial bladder cancer patients after intravesical immunotherapy with bacillus Calmette-Guerin

1 reference

12 December 2020

Intravesical Evans strain BCG therapy: quantitative immunohistochemical analysis of the immune response within the bladder wall

1 reference

12 December 2020

T-cell subsets required for intravesical BCG immunotherapy for bladder cancer

1 reference

12 December 2020

LAK cell mediated apoptosis of human bladder cancer cells involves a pH-dependent endonuclease system in the cancer cell: possible mechanism of BCG therapy

1 reference

12 December 2020

Recombinant BCG therapy suppresses melanoma tumor growth

1 reference

12 December 2020

Local immunotherapy of superficial bladder cancer by intravesical instillation of recombinant interleukin-2

1 reference

12 December 2020

Treatment of superficial bladder cancer with intravesical perfusion of rIL-2: a follow-up study

1 reference

12 December 2020

Intravesical interleukin-2 in T1 papillary bladder carcinoma: regression of marker lesion in 8 of 10 patients

1 reference

12 December 2020

Systemic immune response after intravesical instillation of bacille Calmette-Guérin (BCG) for superficial bladder cancer

1 reference

12 December 2020

A new approach in the management of urothelial tumors using GM-CSF on marker lesions: an ultrastructural and immunohistochemical study on the macrophage population in bladder mucosa

1 reference

12 December 2020

Enhancing the immunotherapeutic potential of mycobacteria by transfection with tumour necrosis factor-alpha

1 reference

12 December 2020

An in vivo comparison of bacillus Calmette-Guérin (BCG) and cytokine-secreting BCG vaccines

1 reference

12 December 2020

Role of IL-12 in the induction and potentiation of IFN-gamma in response to bacillus Calmette-Guérin

1 reference

12 December 2020

Mycobacterium bovis bacille Calmette Guerin infection of human neutrophils induces CXCL8 secretion by MyD88-dependent TLR2 and TLR4 activation

1 reference

12 December 2020

Recombinant Mycobacterium bovis BCG producing IL-18 reduces IL-5 production and bronchoalveolar eosinophilia induced by an allergic reaction

1 reference

12 December 2020

Final results from a national multicenter phase II trial of combination bacillus Calmette-Guérin plus interferon alpha-2B for reducing recurrence of superficial bladder cancer

1 reference

12 December 2020

Identifiers

DOI

10.1155/2011/728930

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21941579%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21941579%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

PubMed publication ID

21941579

1 reference