Perilipin 5 regulates islet lipid metabolism and insulin secretion in a cAMP-dependent manner: implication of its role in the postprandial insulin secretion. (Q35220582)

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English	Perilipin 5 regulates islet lipid metabolism and insulin secretion in a cAMP-dependent manner: implication of its role in the postprandial insulin secretion.	scientific article

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22 February 2020

Perilipin 5 regulates islet lipid metabolism and insulin secretion in a cAMP-dependent manner: implication of its role in the postprandial insulin secretion (English)

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22 February 2020

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22 February 2020

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Michelle B Trevino

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Yui Machida

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Daniel R Hallinger

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Eden Garcia

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Aaron Christensen

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Sucharita Dutta

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22 February 2020

David A Peake

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Yasuhiro Ikeda

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12 November 2014

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22 February 2020

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22 February 2020

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22 February 2020

1299-1310

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22 February 2020

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Increased glucose metabolism and glycerolipid formation by fatty acids and GPR40 receptor signaling underlies the fatty acid potentiation of insulin secretion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375085

13 July 2018

Perilipin 5, a lipid droplet protein adapted to mitochondrial energy utilization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375085

13 July 2018

Desnutrin/ATGL activates PPARδ to promote mitochondrial function for insulin secretion in islet β cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375085

13 July 2018

The biophysics and cell biology of lipid droplets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375085

13 July 2018

Lysosomal acid lipase and lipophagy are constitutive negative regulators of glucose-stimulated insulin secretion from pancreatic beta cells.

1 reference

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13 July 2018

Activation of GPR40 as a therapeutic target for the treatment of type 2 diabetes

1 reference

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13 July 2018

Metabolic signaling in fuel-induced insulin secretion

1 reference

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13 July 2018

Pharmacology, physiology, and mechanisms of incretin hormone action

1 reference

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13 July 2018

Islet β cell mass in diabetes and how it relates to function, birth, and death

1 reference

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13 July 2018

β-Cell-specific protein kinase A activation enhances the efficiency of glucose control by increasing acute-phase insulin secretion

1 reference

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13 July 2018

Cardiomyocyte-specific perilipin 5 overexpression leads to myocardial steatosis and modest cardiac dysfunction

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13 July 2018

Cardiac-specific overexpression of perilipin 5 provokes severe cardiac steatosis via the formation of a lipolytic barrier

1 reference

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13 July 2018

Studies on the substrate and stereo/regioselectivity of adipose triglyceride lipase, hormone-sensitive lipase, and diacylglycerol-O-acyltransferases

1 reference

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13 July 2018

Cyclic AMP dynamics in the pancreatic β-cell

1 reference

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13 July 2018

C/EBPα promotes transcription of the porcine perilipin5 gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375085

13 July 2018

Perilipin family members preferentially sequester to either triacylglycerol-specific or cholesteryl-ester-specific intracellular lipid storage droplets.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375085

13 July 2018

LSDP5 enhances triglyceride storage in hepatocytes by influencing lipolysis and fatty acid β-oxidation of lipid droplets

1 reference

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13 July 2018

Perilipin 5, a lipid droplet-binding protein, protects heart from oxidative burden by sequestering fatty acid from excessive oxidation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375085

13 July 2018

The lipid droplet coat protein perilipin 5 also localizes to muscle mitochondria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375085

13 July 2018

Glycerolipid/free fatty acid cycle and islet β-cell function in health, obesity and diabetes

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ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1.

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13 July 2018

Serum lipidomics profiling using LC-MS and high-energy collisional dissociation fragmentation: focus on triglyceride detection and characterization

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13 July 2018

The role of lipid droplets in metabolic disease in rodents and humans

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13 July 2018

Unique regulation of adipose triglyceride lipase (ATGL) by perilipin 5, a lipid droplet-associated protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375085

13 July 2018

Lipidomics profiling by high-resolution LC-MS and high-energy collisional dissociation fragmentation: focus on characterization of mitochondrial cardiolipins and monolysocardiolipins

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375085

13 July 2018

Interactions of perilipin-5 (Plin5) with adipose triglyceride lipase

1 reference

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13 July 2018

Adipose differentiation-related protein regulates lipids and insulin in pancreatic islets

1 reference

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13 July 2018

Adipose triglyceride lipase is implicated in fuel- and non-fuel-stimulated insulin secretion

1 reference

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13 July 2018

Perilipin is present in islets of Langerhans and protects against lipotoxicity when overexpressed in the beta-cell line INS-1

1 reference

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13 July 2018

Functional interactions between Mldp (LSDP5) and Abhd5 in the control of intracellular lipid accumulation

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13 July 2018

Lipid droplets in lipogenesis and lipolysis

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13 July 2018

Thematic review series: adipocyte biology. The perilipin family of structural lipid droplet proteins: stabilization of lipid droplets and control of lipolysis

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13 July 2018

Insulin secretion is increased in pancreatic islets of neuropeptide Y-deficient mice

1 reference

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13 July 2018

GPR40 is necessary but not sufficient for fatty acid stimulation of insulin secretion in vivo.

1 reference

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13 July 2018

OXPAT/PAT-1 is a PPAR-induced lipid droplet protein that promotes fatty acid utilization

1 reference

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13 July 2018

MLDP, a novel PAT family protein localized to lipid droplets and enriched in the heart, is regulated by peroxisome proliferator-activated receptor alpha

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ADRP/adipophilin is degraded through the proteasome-dependent pathway during regression of lipid-storing cells

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13 July 2018

Post-translational regulation of adipose differentiation-related protein by the ubiquitin/proteasome pathway

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13 July 2018

Oleic acid interacts with GPR40 to induce Ca2+ signaling in rat islet beta-cells: mediation by PLC and L-type Ca2+ channel and link to insulin release

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13 July 2018

Fatty acid metabolism and insulin secretion in pancreatic beta cells

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13 July 2018

Circulating fatty acids are essential for efficient glucose-stimulated insulin secretion after prolonged fasting in humans

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13 July 2018

Mechanisms of the stimulation of insulin release by saturated fatty acids. A study of palmitate effects in mouse beta-cells

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13 July 2018

The stimulus-secretion coupling of glucose-induced insulin release: fuel metabolism in islets deprived of exogenous nutrient

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13 July 2018

The Effect of Fasting on Tissue Cyclic cAMP and Plasma Glucagon in the Obese Hyperglycemic Mouse

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13 July 2018

β-cell metabolic alterations under chronic nutrient overload in rat and human islets

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26 September 2018

The loss of postprandial glycemic control precedes stepwise deterioration of fasting with worsening diabetes.

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26 September 2018

LSDP5 is a PAT protein specifically expressed in fatty acid oxidizing tissues.

1 reference

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26 September 2018

Prevalence and correlates of post-prandial hyperglycaemia in a large sample of patients with type 2 diabetes mellitus.

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26 September 2018

Long-term results of the Kumamoto Study on optimal diabetes control in type 2 diabetic patients.

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26 September 2018

α/β-Hydrolase domain-6-accessible monoacylglycerol controls glucose-stimulated insulin secretion

1 reference

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12 December 2020

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22 February 2020

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22 February 2020

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