Antidiabetic actions of a non-agonist PPARγ ligand blocking Cdk5-mediated phosphorylation (Q35230678)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21892191%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

title

Antidiabetic actions of a non-agonist PPARγ ligand blocking Cdk5-mediated phosphorylation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21892191%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21892191%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Michael J. Jurczak

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21892191%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Gerald I. Shulman

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21892191%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

15

Stephan C Schürer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21892191%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

3

Theodore M Kamenecka

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21892191%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

author name string

Jang Hyun Choi

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21892191%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Scott A Busby

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21892191%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Michael J Chalmers

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21892191%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Naresh Kumar

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21892191%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Dana S Kuruvilla

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21892191%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Youseung Shin

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21892191%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Yuanjun He

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21892191%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

John B Bruning

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21892191%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

David P Marciano

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21892191%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Michael D Cameron

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21892191%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Dina Laznik

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21892191%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Dušica Vidović

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21892191%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Patrick R Griffin

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21892191%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Bruce M Spiegelman

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21892191%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

language of work or name

English

0 references

publication date

4 September 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21892191%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21892191%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

volume

477

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21892191%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

page(s)

477-481

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21892191%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

issue

7365

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21892191%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/nature10383

12 February 2020

exact match

0 references

cites work

Rosiglitazone, PPARγ, and type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179551

Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARgamma by Cdk5.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179551

Rosiglitazone-associated fractures in type 2 diabetes: an Analysis from A Diabetes Outcome Progression Trial (ADOPT).

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179551

The peroxisome proliferator-activated receptor-gamma agonist rosiglitazone decreases bone formation and bone mineral density in healthy postmenopausal women: a randomized, controlled trial

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179551

Hydrogen/deuterium-exchange (H/D-Ex) of PPARgamma LBD in the presence of various modulators

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179551

Thiazolidinedione use, fluid retention, and congestive heart failure: a consensus statement from the American Heart Association and American Diabetes Association

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179551

Distinct properties and advantages of a novel peroxisome proliferator-activated protein [gamma] selective modulator

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179551

The effects of rosiglitazone on insulin sensitivity, lipolysis, and hepatic and skeletal muscle triglyceride content in patients with type 2 diabetes

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179551

A unique PPARgamma ligand with potent insulin-sensitizing yet weak adipogenic activity

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179551

Peroxisome proliferator-activated receptor gamma and metabolic disease.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179551

Nonhypoglycemic effects of thiazolidinediones

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179551

Inhibition of Osf2/Cbfa1 expression and terminal osteoblast differentiation by PPARgamma2.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179551

N-(2-Benzoylphenyl)-L-tyrosine PPARgamma agonists. 1. Discovery of a novel series of potent antihyperglycemic and antihyperlipidemic agents

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179551

Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-gamma

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179551

AdipoQ is a novel adipose-specific gene dysregulated in obesity

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179551

15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179551

PITALRE, a nuclear CDC2-related protein kinase that phosphorylates the retinoblastoma protein in vitro

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179551

Peroxisome proliferator-activated receptor (PPAR) gamma: adipose-predominant expression and induction early in adipocyte differentiation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179551

Improvement in glucose tolerance and insulin resistance in obese subjects treated with troglitazone

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179551

An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma)

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179551

Severely impaired adipsin expression in genetic and acquired obesity

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179551

Glucose clamp technique: a method for quantifying insulin secretion and resistance

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179551

Synthesis and biological activities of novel indole derivatives as potent and selective PPARgamma modulators

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179551

Partial agonists activate PPARgamma using a helix 12 independent mechanism

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179551

A two-stage differential hydrogen deuterium exchange method for the rapid characterization of protein/ligand interactions.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179551

Differential effects of interleukin-6 and -10 on skeletal muscle and liver insulin action in vivo

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179551

A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179551

Stimulation of adipogenesis in fibroblasts by PPAR gamma 2, a lipid-activated transcription factor

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179551

26 September 2018

Identifiers

DOI

10.1038/NATURE10383

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21892191%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

12 February 2020

1004606531

0 references

Fatcat ID

release_7pgcp4pq7bgwpa7vdipeogxlmi

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/7pgcp4pq7bgwpa7vdipeogxlmi

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21892191%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1 reference