Alzheimer's disease is not "brain aging": neuropathological, genetic, and epidemiological human studies (Q35231770)

7 August 2017

1 reference

title

Alzheimer's disease is not "brain aging": neuropathological, genetic, and epidemiological human studies (English)

1 reference

7 August 2017

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1 reference

Peter T Nelson

1

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7 August 2017

Elizabeth Head

2

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7 August 2017

Frederick A Schmitt

3

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7 August 2017

Paulina R Davis

4

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7 August 2017

Janna H Neltner

5

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7 August 2017

Gregory A Jicha

6

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7 August 2017

Erin L Abner

7

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7 August 2017

Charles D Smith

8

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7 August 2017

Linda J Van Eldik

9

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7 August 2017

Richard J Kryscio

10

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7 August 2017

Stephen W Scheff

11

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7 August 2017

24 April 2011

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7 August 2017

Acta Neuropathologica

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7 August 2017

121

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7 August 2017

571-587

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7 August 2017

5

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https://scigraph.springernature.com/pub.10.1007/s00401-011-0826-y

7 August 2017

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13 July 2018

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13 July 2018

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Trade-off in the effects of the apolipoprotein E polymorphism on the ages at onset of CVD and cancer influences human lifespan

13 July 2018

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Association of polypharmacy with nutritional status, functional ability and cognitive capacity over a three-year period in an elderly population

13 July 2018

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Epidemiology of Alzheimer disease

13 July 2018

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Trends in the incidence and prevalence of Alzheimer's disease, dementia, and cognitive impairment in the United States

13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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Vitamin E and all-cause mortality: a meta-analysis

13 July 2018

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Duplication of amyloid precursor protein (APP), but not prion protein (PRNP) gene is a significant cause of early onset dementia in a large UK series

13 July 2018

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Prevalence estimates for latent neurodegenerative disease

13 July 2018

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Reimagining Alzheimer's disease--an age-based hypothesis

13 July 2018

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Investigation of 15 of the top candidate genes for late-onset Alzheimer's disease

13 July 2018

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Systems biology of ageing and longevity

13 July 2018

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Do sleep complaints contribute to age-related cognitive decline?

13 July 2018

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Frontal lobe white matter hyperintensities and neurofibrillary pathology in the oldest old.

13 July 2018

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The genetics of Alzheimer disease: back to the future

13 July 2018

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13 July 2018

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Is there pure vascular dementia in old age?

13 July 2018

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The senescence pathway in prostatic carcinogenesis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Is brain amyloid production a cause or a result of dementia of the Alzheimer's type?

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Neurodegenerative basis of age-related cognitive decline

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Insulin resistance and Alzheimer-like reductions in regional cerebral glucose metabolism for cognitively normal adults with prediabetes or early type 2 diabetes.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Brain aging in the oldest-old

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

The clinical importance of white matter hyperintensities on brain magnetic resonance imaging: systematic review and meta-analysis

13 July 2018

1 reference

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Progeria syndromes and ageing: what is the connection?

13 July 2018

1 reference

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Age, Alzheimer's disease and dementia in the Baltimore Longitudinal Study of Ageing

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Neuropathology after active Abeta42 immunotherapy: implications for Alzheimer's disease pathogenesis.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Genetic variation and neuroimaging measures in Alzheimer disease

13 July 2018

1 reference

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A single ascending dose study of bapineuzumab in patients with Alzheimer disease

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Genome-wide analysis of genetic loci associated with Alzheimer disease

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Thinking outside the box: Alzheimer-type neuropathology that does not map directly onto current consensus recommendations

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Beneficial effect of human anti-amyloid-beta active immunization on neurite morphology and tau pathology

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Caspase activation precedes and leads to tangles

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Dementia incidence continues to increase with age in the oldest old: the 90+ study

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Validation of anti-aging drugs by treating age-related diseases

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Role of oxidative stress in the progression of Alzheimer's disease

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Sirtuins as novel targets for Alzheimer's disease and other neurodegenerative disorders: experimental and genetic evidence

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

A phase 2 multiple ascending dose trial of bapineuzumab in mild to moderate Alzheimer disease

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Cancer and aging: the molecular pathways

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

The neuropathology of older persons with and without dementia from community versus clinic cohorts

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Neuropathologic studies of the Baltimore Longitudinal Study of Aging (BLSA)

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Chronic Traumatic Encephalopathy in Athletes: Progressive Tauopathy After Repetitive Head Injury

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Brains with medial temporal lobe neurofibrillary tangles but no neuritic amyloid plaques are a diagnostic dilemma but may have pathogenetic aspects distinct from Alzheimer disease.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Transmission and spreading of tauopathy in transgenic mouse brain

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Comparison of 18F-FDG and PiB PET in cognitive impairment

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Neuropathology of nondemented aging: presumptive evidence for preclinical Alzheimer disease

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Resveratrol and neurodegenerative diseases: activation of SIRT1 as the potential pathway towards neuroprotection

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapy

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Propagation of tau misfolding from the outside to the inside of a cell.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

The role of metabolic disorders in Alzheimer disease and vascular dementia: two roads converged

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Different patterns of cerebral injury in dementia with or without diabetes

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Neuropathology and cognitive impairment in Alzheimer disease: a complex but coherent relationship

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Criteria for the neuropathological diagnosis of dementing disorders: routes out of the swamp?

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Modeling the association between 43 different clinical and pathological variables and the severity of cognitive impairment in a large autopsy cohort of elderly persons

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Alzheimer's-type neuropathology in the precuneus is not increased relative to other areas of neocortex across a range of cognitive impairment

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Diet-induced metabolic disturbances as modulators of brain homeostasis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Human cerebral neuropathology of Type 2 diabetes mellitus

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Role of the neuropathology of Alzheimer disease in dementia in the oldest-old

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Age and apoE associations with complex pathologic features in Alzheimer's disease

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Long-term effects of Abeta42 immunisation in Alzheimer's disease: follow-up of a randomised, placebo-controlled phase I trial

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

The pathology of "vascular dementia": a critical update

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Abnormal TDP-43 immunoreactivity in AD modifies clinicopathologic and radiologic phenotype.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Staging of neurofibrillary pathology in Alzheimer's disease: a study of the BrainNet Europe Consortium

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

The Sun Health Research Institute Brain Donation Program: description and experience, 1987-2007

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Leukoencephalopathies associated with inborn errors of metabolism in adults

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Modulation of sirtuins: new targets for antiageing.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Clinicopathologic correlations in a large Alzheimer disease center autopsy cohort: neuritic plaques and neurofibrillary tangles "do count" when staging disease severity

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Oxidatively modified RNA in mild cognitive impairment

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Identification of Alzheimer and vascular lesion thresholds for mixed dementia

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

The National Alzheimer's Coordinating Center (NACC) database: the Uniform Data Set.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Hypothesis: lifespan is regulated by chronomere DNA of the hypothalamus.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Oxidative damage in mild cognitive impairment and early Alzheimer's disease

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Subcortical infarcts, Alzheimer's disease pathology, and memory function in older persons

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Characterization of Japanese-American men with a single neocortical AD lesion type

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Neuropathology and treatment of Alzheimer disease: did we lose the forest for the trees?

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Biological aging is no longer an unsolved problem

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Life and death of neurons in the aging cerebral cortex

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Neuropathological evaluation of mixed dementia.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Morphological substrates of cognitive decline in nonagenarians and centenarians: a new paradigm?

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

The use of histology in 638 coronial post-mortem examinations of adults: an audit

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Developing master keys to brain pathology, cancer and aging from the structural biology of proteins controlling reactive oxygen species and DNA repair.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Mitochondrial dysfunction, free radical generation and cellular stress response in neurodegenerative disorders

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Assessing the cognitive impact of Alzheimer disease pathology and vascular burden in the aging brain: the Geneva experience

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

APP duplication is sufficient to cause early onset Alzheimer's dementia with cerebral amyloid angiopathy

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Aging: progeria and the lamin connection

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Alzheimer's disease-related alterations in synaptic density: neocortex and hippocampus.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Involvement of oxidative stress in Alzheimer disease

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Mitochondria: dynamic organelles in disease, aging, and development

13 July 2018

1 reference

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Promoter mutations that increase amyloid precursor-protein expression are associated with Alzheimer disease

13 July 2018

1 reference

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Insulin resistance, inflammation, and cognition in Alzheimer's Disease: lessons for multiple sclerosis

13 July 2018

1 reference

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Characterizing sleep problems in persons with Alzheimer's disease and normal elderly

13 July 2018

1 reference

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Molecular genetics of Alzheimer's disease and aging

13 July 2018

1 reference

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Role of Genes and Environments for Explaining Alzheimer Disease

13 July 2018

1 reference

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Population-based neuropathological studies of dementia: design, methods and areas of investigation--a systematic review

13 July 2018

1 reference

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Overestimation of clinical diagnostic performance caused by low necropsy rates

13 July 2018

1 reference

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Discrepancies between clinical and autopsy diagnosis and the value of post mortem histology; a meta-analysis and review

13 July 2018

1 reference

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13 July 2018

1 reference

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Preclinical Alzheimer's disease: diagnosis and prediction of progression

13 July 2018

1 reference

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Amyloid mediates the association of apolipoprotein E e4 allele to cognitive function in older people

13 July 2018

1 reference

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Molecular mechanisms of aging-associated inflammation

13 July 2018

1 reference

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Type 2 diabetes is negatively associated with Alzheimer's disease neuropathology

13 July 2018

1 reference

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Cognitive consequences of thalamic, basal ganglia, and deep white matter lacunes in brain aging and dementia

13 July 2018

1 reference

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Genetic alterations in accelerated ageing syndromes. Do they play a role in natural ageing?

13 July 2018

1 reference

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Genetic modulation of senescent phenotypes in Homo sapiens

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Multiple roads to the aging phenotype: insights from the molecular dissection of progerias through DNA microarray analysis

13 July 2018

1 reference

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Vascular pathologies and cognition in a population-based cohort of elderly people

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Neurodegeneration in normal brain aging and disease.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Alzheimer's amyloid beta-peptide (1-42): involvement of methionine residue 35 in the oxidative stress and neurotoxicity properties of this peptide

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

The biology of aging in model organisms.

13 July 2018

1 reference

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Cognitive deficits in preclinical Alzheimer's disease.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Apolipoprotein E epsilon4 allele, AD pathology, and the clinical expression of Alzheimer's disease

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Stereologic evidence for persistence of viable neurons in layer II of the entorhinal cortex and the CA1 field in Alzheimer disease

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Cerebrovascular pathology and dementia in autopsied Honolulu-Asia Aging Study participants

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Relative frequencies of Alzheimer disease, Lewy body, vascular and frontotemporal dementia, and hippocampal sclerosis in the State of Florida Brain Bank

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Is oxidative damage the fundamental pathogenic mechanism of Alzheimer's and other neurodegenerative diseases?

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Clinical and neuropathological characteristics of hippocampal sclerosis: a community-based study

13 July 2018

1 reference

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13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Changing complexity in human behavior and physiology through aging and disease

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Apolipoprotein E modulates Alzheimer's Abeta(1-42)-induced oxidative damage to synaptosomes in an allele-specific manner

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

The effects of age on rate of progression of Alzheimer disease and dementia with associated cerebrovascular disease

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Pathological correlates of late-onset dementia in a multicentre, community-based population in England and Wales. Neuropathology Group of the Medical Research Council Cognitive Function and Ageing Study (MRC CFAS).

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Modulation of amyloid beta-protein clearance and Alzheimer's disease susceptibility by the LDL receptor-related protein pathway.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

The biochemistry of aging

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

The relative frequency of "dementia of unknown etiology" increases with age and is nearly 50% in nonagenarians

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Pure hippocampal sclerosis: a rare cause of dementia mimicking Alzheimer's disease

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

The progression of Alzheimer's disease from limbic regions to the neocortex: clinical, radiological and pathological relationships.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

The relationships between age, sex, and the incidence of dementia and Alzheimer disease: a meta-analysis.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Incidence of dementia and Alzheimer's disease: a reanalysis of data from Rochester, Minnesota, 1975-1984.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Diabetics do not have increased Alzheimer-type pathology compared with age-matched control subjects. A retrospective postmortem immunocytochemical and histofluorescent study.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Specific hippocampal volume reductions in individuals at risk for Alzheimer's disease.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Neocortical neuron number in humans: effect of sex and age.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Brain infarction and the clinical expression of Alzheimer disease. The Nun Study

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Cancer of the oldest old. What we have learned from autopsy studies

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

The neuropathological changes associated with normal brain aging

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Preclinical evidence of Alzheimer's disease in persons homozygous for the epsilon 4 allele for apolipoprotein E.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Staging of Alzheimer-related cortical destruction

13 July 2018

1 reference

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Synaptic pathology of Alzheimer's disease

13 July 2018

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Mechanisms of synaptic dysfunction in Alzheimer's disease.

13 July 2018

1 reference

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Correlations of synaptic and pathological markers with cognition of the elderly

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Observations on the brains of demented old people

13 July 2018

1 reference

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A comparison of adult and childhood progerias: Werner syndrome and Hutchinson-Gilford progeria syndrome

13 July 2018

1 reference

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Genetic modulation of the senescent phenotype in Homo sapiens

13 July 2018

1 reference

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The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer's disease

13 July 2018

1 reference

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The influence of major depression on clinical and psychometric assessment of senile dementia of the Alzheimer type.

13 July 2018

1 reference

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Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease

13 July 2018

1 reference

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Neuropathological background of twenty-seven centenarian brains

13 July 2018

1 reference

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Synaptic density in human frontal cortex — Developmental changes and effects of aging

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Comment on: Hippocampal sclerosis in advanced age: clinical and pathological features: Nelson PT, Schmitt FA, Lin Y et al (2011). Brain 134:1506-1518. doi:10.1093/brain/awr053.

13 July 2018

1 reference

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Prevalence and pathology of vascular dementia in the oldest-old.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

TAR-DNA binding protein-43 and alterations in the hippocampus.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Revising the definition of Alzheimer's disease: a new lexicon.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Insulin resistance is associated with the pathology of Alzheimer disease: the Hisayama study

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Diabetes, Alzheimer disease, and vascular dementia: a population-based neuropathologic study

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Reduction of aggregated Tau in neuronal processes but not in the cell bodies after Abeta42 immunisation in Alzheimer's disease.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Prevalence of dementia disorders in the oldest-old: an autopsy study.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Clinical spectrum of CADASIL and the effect of cardiovascular risk factors on phenotype: study in 200 consecutively recruited individuals

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Gender and health outcomes: the impact of healthcare systems and their financing on life expectancies of women and men.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Age, neuropathology, and dementia.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Clinical correlates of cerebral white matter hyperintensities in cognitively normal older adults.

26 September 2018

1 reference

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Neurofibrillary changes of the Alzheimer type in very elderly individuals: neither inevitable nor benign: Commentary on "No disease in the brain of a 115-year-old woman".

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Vascular disease among hospitalized multiple sclerosis patients

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Type 2 diabetes mellitus and cognitive decline in two large cohorts of community-dwelling older adults.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Pathological correlates of dementia in a longitudinal, population-based sample of aging.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Oxidative stress alters neuronal RNA- and protein-synthesis: Implications for neural viability.

26 September 2018

1 reference

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Late-onset Wilson's disease

26 September 2018

1 reference

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Quantitative analysis of neurofibrillary pathology in a general population to reappraise neuropathological criteria for senile dementia of the neurofibrillary tangle type (tangle-only dementia): the Hisayama Study.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Abeta species removal after abeta42 immunization.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Relationship of vascular risk to the progression of Alzheimer disease.

26 September 2018

1 reference

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Dissociation of neuropathology from severity of dementia in late-onset Alzheimer disease.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Recent clinical-pathologic research on the causes of dementia in late life: update from the Honolulu-Asia Aging Study.

26 September 2018

1 reference

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Redox proteomics identification of oxidized proteins in Alzheimer's disease hippocampus and cerebellum: an approach to understand pathological and biochemical alterations in AD.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Dementia incidence may increase more slowly after age 90: results from the Bronx Aging Study.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Measures of brain morphology and infarction in the framingham heart study: establishing what is normal.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

The National Alzheimer's Coordinating Center (NACC) Database: an Alzheimer disease database.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

AD lesions and infarcts in demented and non-demented Japanese-American men.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Neuropathology provides clues to the pathophysiology of Gaucher disease.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Cerebral infarctions and the likelihood of dementia from Alzheimer disease pathology.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Increased risk of type 2 diabetes in Alzheimer disease

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Neuropathology of cognitively normal elderly.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Aging and the human neocortex.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179861

Dementia and Alzheimer disease incidence: a prospective cohort study.

26 September 2018

1 reference

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Depressive symptoms, cognitive decline, and risk of AD in older persons.

26 September 2018

1 reference

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Alzheimer's neurofibrillary pathology and the spectrum of cognitive function: findings from the Nun Study.

26 September 2018

1 reference

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Regional quantitative analysis of NFT in brains of non-demented elderly persons: comparisons with findings in brains of late-onset Alzheimer's disease and limbic NFT dementia.

26 September 2018

1 reference

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Degenerative and vascular lesions of the brain have synergistic effects in dementia of the elderly

26 September 2018

1 reference

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Type 2 diabetes, APOE gene, and the risk for dementia and related pathologies: The Honolulu-Asia Aging Study

26 September 2018

1 reference

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The effects of AbetaPP mutations and APOE polymorphisms on cerebral amyloid angiopathy

26 September 2018

1 reference

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Trend of stroke hospitalization, United States, 1988-1997.

26 September 2018

1 reference

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Quantitative assessment of possible age-related change in synaptic numbers in the human frontal cortex.

26 September 2018

1 reference

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"Preclinical" AD revisited: neuropathology of cognitively normal older adults.

26 September 2018

1 reference

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Clinical validity of Braak neuropathological staging in the oldest-old

26 September 2018

1 reference

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Novel twelve-generation kindred of fatal familial insomnia from germany representing the entire spectrum of disease expression.

26 September 2018

1 reference

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Preclinical memory decline in cognitively normal apolipoprotein E-epsilon4 homozygotes.

26 September 2018

1 reference

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Aging-associated neuropathology in Werner syndrome.

26 September 2018

1 reference

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Sequence of deposition of heterogeneous amyloid beta-peptides and APO E in Down syndrome: implications for initial events in amyloid plaque formation.

26 September 2018

1 reference

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Hippocampal sclerosis contributes to dementia in the elderly

26 September 2018

1 reference

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Synaptic pathology in Alzheimer's disease: relation to severity of dementia, but not to senile plaques, neurofibrillary tangles, or the ApoE4 allele.

26 September 2018

1 reference

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Apolipoprotein E epsilon4 association with dementia in a population-based study: The Framingham study.

26 September 2018

1 reference

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Hippocampal sclerosis: a common pathological feature of dementia in very old humans.

26 September 2018

1 reference

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Hippocampal sclerosis: a common pathological feature of dementia in very old (> or = 80 years of age) humans.

26 September 2018

1 reference

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Correlation between scores for dementia and counts of 'senile plaques' in cerebral grey matter of elderly subjects.

26 September 2018

1 reference

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MRI correlates of neurofibrillary tangle pathology at autopsy: a voxel-based morphometry study

26 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00401-011-0826-Y

21 January 2018

1 reference

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https://api.crossref.org/works/10.1007%2FS00401-011-0826-Y

Consensus recommendations for the postmortem diagnosis of Alzheimer's disease. The National Institute on Aging, and Reagan Institute Working Group on Diagnostic Criteria for the Neuropathological Assessment of Alzheimer's Disease

21 January 2018

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12 December 2020

Presence of apolipoprotein E epsilon4 allele predisposes to early onset of primary Sjogren's syndrome

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12 December 2020

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12 December 2020

Oxidative stress and aging

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12 December 2020

Prevalence of stroke--United States, 2005

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12 December 2020

Co-expression of beta-amyloid precursor protein (betaAPP) and apolipoprotein E in cell culture: analysis of betaAPP processing

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12 December 2020

Cerebral cortex pathology in aging and Alzheimer's disease: a quantitative survey of large hospital-based geriatric and psychiatric cohorts

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12 December 2020

Tapping the SEER database

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12 December 2020

Pure hippocampal sclerosis: a rare cause of dementia mimicking Alzheimer's disease

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12 December 2020

Neuropathological findings in the very old. Results from the first 101 brains of a population-based longitudinal study of dementing disorders

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12 December 2020

The Georgia Centenarian Study

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12 December 2020

Causes of death and clinical diagnostic errors in extreme aged hospitalized people: a retrospective clinical-necropsy survey

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12 December 2020

Type 2 diabetes mellitus and cognition: an understudied issue in women's health

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12 December 2020

The pathological process underlying Alzheimer's disease in individuals under thirty

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12 December 2020

Relation between age-related decline in intelligence and cerebral white-matter hyperintensities in healthy octogenarians: a longitudinal study

1 reference

12 December 2020

Survival in Alzheimer's disease is shorter in women carrying heterozygosity at codon 129 of the PRNP gene and no APOE epsilon 4 allele

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12 December 2020

Brain MR: pathologic correlation with gross and histopathology. 2. Hyperintense white-matter foci in the elderly

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10.1007/S00401-011-0826-Y

Identifiers

DOI

1 reference

7 August 2017

1 reference

7 August 2017

1 reference