Brr2 plays a role in spliceosomal activation in addition to U4/U6 unwinding (Q35237021)

7 August 2017

title

Brr2 plays a role in spliceosomal activation in addition to U4/U6 unwinding (English)

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7 August 2017

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Lingdi Zhang

1

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7 August 2017

Xueni Li

2

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7 August 2017

Ryan C Hill

3

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7 August 2017

Yan Qiu

4

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7 August 2017

Wenzheng Zhang

5

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7 August 2017

Kirk C Hansen

6

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7 August 2017

Rui Zhao

7

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7 August 2017

language of work or name

English

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publication date

10 February 2015

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7 August 2017

published in

Nucleic Acids Research

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7 August 2017

volume

43

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7 August 2017

issue

6

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7 August 2017

page(s)

3286-3297

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Creative Commons Attribution 4.0 International

7 August 2017

copyright license

start time

10 November 2016

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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An unanticipated early function of DEAD-box ATPase Prp28 during commitment to splicing is modulated by U5 snRNP protein Prp8.

13 July 2018

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Structural Basis of Brr2-Prp8 Interactions and Implications for U5 snRNP Biogenesis and the Spliceosome Active Site

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Comprehensive in vivo RNA-binding site analyses reveal a role of Prp8 in spliceosomal assembly

13 July 2018

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Brr2p-mediated conformational rearrangements in the spliceosome during activation and substrate repositioning

13 July 2018

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Structural basis for functional cooperation between tandem helicase cassettes in Brr2-mediated remodeling of the spliceosome

13 July 2018

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A novel missense SNRNP200 mutation associated with autosomal dominant retinitis pigmentosa in a Chinese family

13 July 2018

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The evolutionarily conserved core design of the catalytic activation step of the yeast spliceosome

13 July 2018

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Autosomal-dominant retinitis pigmentosa caused by a mutation in SNRNP200, a gene required for unwinding of U4/U6 snRNAs

13 July 2018

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Structural evidence for consecutive Hel308-like modules in the spliceosomal ATPase Brr2

13 July 2018

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13 July 2018

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A dynamic bulge in the U6 RNA internal stem-loop functions in spliceosome assembly and activation.

13 July 2018

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Transcript specificity in yeast pre-mRNA splicing revealed by mutations in core spliceosomal components

13 July 2018

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The EF-G-like GTPase Snu114p regulates spliceosome dynamics mediated by Brr2p, a DExD/H box ATPase

13 July 2018

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Tube-gel digestion: a novel proteomic approach for high throughput analysis of membrane proteins

13 July 2018

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Genetic analysis reveals a role for the C terminus of the Saccharomyces cerevisiae GTPase Snu114 during spliceosome activation

13 July 2018

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Prp8 protein: at the heart of the spliceosome

13 July 2018

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13 July 2018

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Pre-mRNA splicing: awash in a sea of proteins

13 July 2018

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13 July 2018

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Allosteric cascade of spliceosome activation

13 July 2018

1 reference

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The ribosomal translocase homologue Snu114p is involved in unwinding U4/U6 RNA during activation of the spliceosome

13 July 2018

1 reference

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Composition and functional characterization of the yeast spliceosomal penta-snRNP.

13 July 2018

1 reference

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Biochemical and genetic analyses of the U5, U6, and U4/U6 x U5 small nuclear ribonucleoproteins from Saccharomyces cerevisiae

13 July 2018

1 reference

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Pre-mRNA splicing in the new millennium

13 July 2018

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Functional contacts with a range of splicing proteins suggest a central role for Brr2p in the dynamic control of the order of events in spliceosomes of Saccharomyces cerevisiae

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4381053

The first ATPase domain of the yeast 246-kDa protein is required for in vivo unwinding of the U4/U6 duplex

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4381053

An RNA switch at the 5' splice site requires ATP and the DEAD box protein Prp28p

13 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4381053

RNA unwinding in U4/U6 snRNPs requires ATP hydrolysis and the DEIH-box splicing factor Brr2

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4381053

The human U5-200kD DEXH-box protein unwinds U4/U6 RNA duplices in vitro

13 July 2018

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Mechanical devices of the spliceosome: motors, clocks, springs, and things

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4381053

The HeLa 200 kDa U5 snRNP-specific protein and its homologue in Saccharomyces cerevisiae are members of the DEXH-box protein family of putative RNA helicases

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4381053

A rapid assay for quantitative detection of specific RNAs

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4381053

Retinitis pigmentosa mutations of SNRNP200 enhance cryptic splice-site recognition.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4381053

Next generation sequencing of pooled samples reveals new SNRNP200 mutations associated with retinitis pigmentosa

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4381053

Common design principles in the spliceosomal RNA helicase Brr2 and in the Hel308 DNA helicase.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4381053

Splicing factor Prp8 governs U4/U6 RNA unwinding during activation of the spliceosome

26 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25670679

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/NAR/GKV062

1 reference

7 August 2017

1 reference

7 August 2017

1 reference