Oncolytic adenovirus expressing soluble TGFβ receptor II-Fc-mediated inhibition of established bone metastases: a safe and effective systemic therapeutic approach for breast cancer (Q35238261)

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English	Oncolytic adenovirus expressing soluble TGFβ receptor II-Fc-mediated inhibition of established bone metastases: a safe and effective systemic therapeutic approach for breast cancer	scientific article

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

Oncolytic adenovirus expressing soluble TGFβ receptor II-Fc-mediated inhibition of established bone metastases: a safe and effective systemic therapeutic approach for breast cancer (English)

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

oncolytic virus

1 reference

based on heuristic

inferred from title

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based on heuristic

inferred from title

author name string

Zebin Hu

1

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

Helen Gerseny

2

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

Zhenwei Zhang

3

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

Yun-Ju Chen

4

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

Arthur Berg

5

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

Zhiling Zhang

6

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

Stuart Stock

7

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

Prem Seth

8

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

publication date

28 June 2011

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Europe PubMed Central

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7 August 2017

Molecular Therapy

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Europe PubMed Central

PubMed publication ID

7 August 2017

19

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Europe PubMed Central

PubMed publication ID

7 August 2017

9

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

1609-1618

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

TGFβ-dependent induction of interleukin-11 and interleukin-8 involves SMAD and p38 MAPK pathways in breast tumor models with varied bone metastases potential

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182349

13 July 2018

Telomerase-dependent oncolytic adenovirus sensitizes human cancer cells to ionizing radiation via inhibition of DNA repair machinery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182349

13 July 2018

Future directions of bone-targeted therapy for metastatic breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182349

13 July 2018

Systemic delivery of an oncolytic adenovirus expressing soluble transforming growth factor-β receptor II-Fc fusion protein can inhibit breast cancer bone metastasis in a mouse model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182349

13 July 2018

Current issues and future directions of oncolytic adenoviruses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182349

13 July 2018

A phase I study of telomerase-specific replication competent oncolytic adenovirus (telomelysin) for various solid tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182349

13 July 2018

Selective metastatic tumor labeling with green fluorescent protein and killing by systemic administration of telomerase-dependent adenoviruses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182349

13 July 2018

A modified hTERT promoter-directed oncolytic adenovirus replication with concurrent inhibition of TGFbeta signaling for breast cancer therapy

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182349

13 July 2018

Breaking down bone: new insight into site-specific mechanisms of breast cancer osteolysis mediated by metalloproteinases

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182349

13 July 2018

In vivo internal tumor illumination by telomerase-dependent adenoviral GFP for precise surgical navigation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182349

13 July 2018

The critical role of the bone microenvironment in cancer metastases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182349

13 July 2018

Metastasis: from dissemination to organ-specific colonization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182349

13 July 2018

A phase I trial of intratumoral administration of recombinant oncolytic adenovirus overexpressing HSP70 in advanced solid tumor patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182349

13 July 2018

Roles of TGFbeta in metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182349

13 July 2018

Transforming growth factor-beta signaling: emerging stem cell target in metastatic breast cancer?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182349

13 July 2018

Overcoming the extracellular matrix barrier to improve intratumoral spread and therapeutic potential of oncolytic virotherapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182349

13 July 2018

Adenovirus serotype 5 hexon is critical for virus infection of hepatocytes in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182349

13 July 2018

Metastasis: a therapeutic target for cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182349

13 July 2018

Biology of breast cancer bone metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182349

13 July 2018

Molecular biology of bone metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182349

13 July 2018

Molecular definition of breast tumor heterogeneity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182349

13 July 2018

From ONYX-015 to armed vaccinia viruses: the education and evolution of oncolytic virus development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182349

13 July 2018

Basic mechanisms responsible for osteolytic and osteoblastic bone metastases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182349

13 July 2018

Development of oncolytic adenovirus armed with a fusion of soluble transforming growth factor-beta receptor II and human immunoglobulin Fc for breast cancer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182349

13 July 2018

Inhibition of transforming growth factor-beta signaling in human cancer: targeting a tumor suppressor network as a therapeutic strategy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182349

13 July 2018

Future prospects for oncolytic therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182349

13 July 2018

The multiple uses of fluorescent proteins to visualize cancer in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182349

13 July 2018

Breast cancer bone metastasis mediated by the Smad tumor suppressor pathway

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182349

13 July 2018

Targeting TGFbeta signaling for cancer therapy

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182349

13 July 2018

Disease-Specific Expression of Tartrate-Resistant Acid Phosphatase Isoforms

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182349

13 July 2018

Ad-mTERT-delta19, a conditional replication-competent adenovirus driven by the human telomerase promoter, selectively replicates in and elicits cytopathic effect in a cancer cell-specific manner

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182349

13 July 2018

A multigenic program mediating breast cancer metastasis to bone

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182349

13 July 2018

Metastatic bone disease: clinical features, pathophysiology and treatment strategies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182349

13 July 2018

Evaluation of E1-mutant adenoviruses as conditionally replicating agents for cancer therapy

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182349

13 July 2018

Orthotopic metastatic mouse models for anticancer drug discovery and evaluation: a bridge to the clinic

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182349

13 July 2018

Implication of interfering antibody formation and apoptosis as two different mechanisms leading to variable duration of adenovirus-mediated transgene expression in immune-competent mice

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13 July 2018

TGF-beta signaling blockade inhibits PTHrP secretion by breast cancer cells and bone metastases development

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13 July 2018

Cytotoxic effects of adenovirus-mediated wild-type p53 protein expression in normal and tumor mammary epithelial cells

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An adenovirus mutant that replicates selectively in p53-deficient human tumor cells

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Increased expression of TGF-beta 2 in osteoblasts results in an osteoporosis-like phenotype

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Adenovirus serotype 5 hexon mediates liver gene transfer

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26 September 2018

Acute hepatotoxicity of oncolytic adenoviruses in mouse models is associated with expression of wild-type E1a and induction of TNF-alpha

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Telomerase-dependent oncolytic adenovirus for cancer treatment

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DNA sequence of the deletion/insertion in early region 3 of Ad5 dl309.

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26 September 2018

Breast Cancer Metastasis: Challenges and Opportunities

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Correlation between extent of osteolytic damage and metastatic burden of human breast cancer metastasis in nude mice: real-time PCR quantitation

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7 January 2021

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10.1038/MT.2011.114

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Europe PubMed Central

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7 August 2017

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Europe PubMed Central

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7 August 2017

PubMed publication ID

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Europe PubMed Central

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7 August 2017

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