Htt CAG repeat expansion confers pleiotropic gains of mutant huntingtin function in chromatin regulation (Q35253059)

7 August 2017

title

Htt CAG repeat expansion confers pleiotropic gains of mutant huntingtin function in chromatin regulation (English)

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7 August 2017

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Sonia M Vallabh

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7 August 2017

Marta Biagioli

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Francesco Ferrari

object named as

Francesco Ferrari

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Michael E. Talkowski

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Michael E Talkowski

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James F. Gusella

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object named as

James F Gusella

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7 August 2017

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Marcy E Macdonald

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Poornima Manavalan

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7 August 2017

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Ashok Ragavendran

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7 August 2017

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Ihn Sik Seong

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7 August 2017

Yijing Zhang

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7 August 2017

Ravi Vijayvargia

6

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7 August 2017

Nicole Solomos

8

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7 August 2017

Fatih Ozsolak

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7 August 2017

Jong Min Lee

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7 August 2017

Peter J Park

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7 August 2017

publication date

8 January 2015

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7 August 2017

published in

Human Molecular Genetics

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7 August 2017

volume

24

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7 August 2017

issue

9

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7 August 2017

page(s)

2442-2457

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describes a project that uses

7 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4383859/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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Huntingtin is required for neurogenesis and is not impaired by the Huntington's disease CAG expansion

12 July 2018

1 reference

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A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

12 July 2018

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Targeted disruption of the Huntington's disease gene results in embryonic lethality and behavioral and morphological changes in heterozygotes

12 July 2018

1 reference

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Inactivation of the mouse Huntington's disease gene homolog Hdh

12 July 2018

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Increased apoptosis and early embryonic lethality in mice nullizygous for the Huntington's disease gene homologue

12 July 2018

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HEAT repeats in the Huntington's disease protein

12 July 2018

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Neuropathological classification of Huntington's disease

12 July 2018

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Lack of huntingtin promotes neural stem cells differentiation into glial cells while neurons expressing huntingtin with expanded polyglutamine tracts undergo cell death

12 July 2018

1 reference

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Induced pluripotent stem cells from patients with Huntington's disease show CAG-repeat-expansion-associated phenotypes

26 September 2018

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Normal electrical properties of hippocampal neurons modelling early Huntington disease pathogenesis

26 September 2018

1 reference

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The HD mutation causes progressive lethal neurological disease in mice expressing reduced levels of huntingtin.

26 September 2018

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Generation of a defined and uniform population of CNS progenitors and neurons from mouse embryonic stem cells

26 September 2018

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Crossref

https://api.crossref.org/works/10.1093%2FHMG%2FDDV006

Huntingtin: Alive and Well and Working in Middle Management

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25574027

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/HMG/DDV006

1 reference

7 August 2017

1 reference

7 August 2017

1 reference