An antiapoptotic BCL-2 family expression index predicts the response of chronic lymphocytic leukemia to ABT-737. (Q35266213)

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8 February 2020

title

An antiapoptotic BCL-2 family expression index predicts the response of chronic lymphocytic leukemia to ABT-737 (English)

1 reference

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8 February 2020

0 references

1 reference

chronic lymphocytic leukemia

1 reference

6

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8 February 2020

Alexandru Almasan

11

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8 February 2020

author name string

Sayer Al-Harbi

1

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8 February 2020

Brian T Hill

2

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8 February 2020

Suparna Mazumder

3

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8 February 2020

Kamini Singh

4

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8 February 2020

Jennifer Devecchio

5

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8 February 2020

Lisa A Rybicki

7

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8 February 2020

Matt Kalaycio

8

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8 February 2020

Jaroslaw P Maciejewski

9

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8 February 2020

Janet A Houghton

10

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8 February 2020

language of work or name

English

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publication date

19 July 2011

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8 February 2020

number of pages

12

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inferred from page(s)

published in

Blood

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8 February 2020

volume

118

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8 February 2020

issue

13

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8 February 2020

page(s)

3579-3590

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Phase I study of Navitoclax (ABT-263), a novel Bcl-2 family inhibitor, in patients with small-cell lung cancer and other solid tumors

8 February 2020

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BH3 profiling identifies three distinct classes of apoptotic blocks to predict response to ABT-737 and conventional chemotherapeutic agents

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Mcl-1 down-regulation potentiates ABT-737 lethality by cooperatively inducing Bak activation and Bax translocation

27 July 2018

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Chronic lymphocytic leukemia requires BCL2 to sequester prodeath BIM, explaining sensitivity to BCL2 antagonist ABT-737.

27 July 2018

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The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized.

27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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26 September 2018

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26 September 2018

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26 September 2018

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26 September 2018

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26 September 2018

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ZAP-70 compared with immunoglobulin heavy-chain gene mutation status as a predictor of disease progression in chronic lymphocytic leukemia

26 September 2018

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26 September 2018

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26 September 2018

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26 September 2018

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26 September 2018

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Expression of apoptosis-regulating proteins in chronic lymphocytic leukemia: correlations with In vitro and In vivo chemoresponses.

26 September 2018

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Low MCL-1 mRNA expression correlates with prolonged survival in B-cell chronic lymphocytic leukemia

26 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21772052

12 December 2020

inferred from PubMed ID database lookup

In leukaemic CD5+ B cells the expression of BCL-2 gene family is shifted toward protection from apoptosis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21772052

12 December 2020

inferred from PubMed ID database lookup

Bcl-2/Bax ratios in chronic lymphocytic leukaemia and their correlation with in vitro apoptosis and clinical resistance

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21772052

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1182/BLOOD-2011-03-340364

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21772052%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21772052%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

PubMed publication ID

21772052

1 reference