Intracellular erythrocyte platelet-activating factor acetylhydrolase I inactivates aspirin in blood (Q35266471)

7 August 2017

Intracellular erythrocyte platelet-activating factor acetylhydrolase I inactivates aspirin in blood (English)

1 reference

7 August 2017

1 reference

Gang Zhou

1

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7 August 2017

Gopal K Marathe

series ordinal

2

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7 August 2017

Belinda Willard

series ordinal

3

1 reference

7 August 2017

Thomas M McIntyre

series ordinal

4

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7 August 2017

language of work or name

English

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publication date

15 August 2011

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Journal of Biological Chemistry

7 August 2017

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7 August 2017

286

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7 August 2017

40

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7 August 2017

34820-34829

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Biology of platelet-activating factor acetylhydrolase (PAF-AH, lipoprotein associated phospholipase A2).

7 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186390

The emerging roles of PAF acetylhydrolase

27 July 2018

1 reference

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Crystal Structure of Human Plasma Platelet-activating Factor Acetylhydrolase: STRUCTURAL IMPLICATION TO LIPOPROTEIN BINDING AND CATALYSIS

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186390

A yeast PAF acetylhydrolase ortholog suppresses oxidative death.

27 July 2018

1 reference

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Aspirin and clopidogrel resistance

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186390

Aspirin esterase activity - Evidence for skewed distribution in healthy volunteers

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186390

Drug insight: aspirin resistance-fact or fashion?

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186390

Drug insight: aspirin resistance--fact or fashion?

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186390

Aspirin is a substrate for paraoxonase-like activity: implications in atherosclerosis

27 July 2018

1 reference

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Involvement of human blood arylesterases and liver microsomal carboxylesterases in nafamostat hydrolysis

27 July 2018

1 reference

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Genetic variants in the UGT1A6 enzyme, aspirin use, and the risk of colorectal adenoma

27 July 2018

1 reference

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Cyclooxygenase isozymes: the biology of prostaglandin synthesis and inhibition.

27 July 2018

1 reference

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Aspirin resistance: definition, mechanisms and clinical read-outs

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186390

Targeted disruption of intracellular type I platelet activating factor-acetylhydrolase catalytic subunits causes severe impairment in spermatogenesis

27 July 2018

1 reference

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Cyclooxygenase-3 (COX-3): filling in the gaps toward a COX continuum?

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186390

Platelet-activating factor acetylhydrolase (PAF-AH).

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186390

CYP2C9 and UGT1A6 genotypes modulate the protective effect of aspirin on colon adenoma risk

27 July 2018

1 reference

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The expanding superfamily of phospholipase A(2) enzymes: classification and characterization

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186390

Cyclooxygenases: structural, cellular, and molecular biology

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186390

Biochemical characterization of various catalytic complexes of the brain platelet-activating factor acetylhydrolase

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186390

Probing the substrate specificity of the intracellular brain platelet-activating factor acetylhydrolase

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186390

Brain acetylhydrolase that inactivates platelet-activating factor is a G-protein-like trimer

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186390

Transport of aspirin and its metabolites through human erythrocyte membrane

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186390

The catalytic subunit of bovine brain platelet-activating factor acetylhydrolase is a novel type of serine esterase

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186390

Mammalian tissue acetylsalicylic acid esterase(s): identification, distribution and discrimination from other esterases

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186390

Hydrolysis of ester- and amide-type drugs by the purified isoenzymes of nonspecific carboxylesterase from rat liver.

27 July 2018

1 reference

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Aspirin metabolism and efficacy in postoperative dental pain

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186390

Endogenous biosynthesis of prostacyclin and thromboxane and platelet function during chronic administration of aspirin in man

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186390

Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186390

Clinical pharmacokinetics of the salicylates

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186390

Aspirin in cardiovascular disease

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186390

Pharmacokinetics of aspirin and salicylate in relation to inhibition of arachidonate cyclooxygenase and antiinflammatory activity

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186390

Structure-function relationships in sheep, mouse, and human prostaglandin endoperoxide G/H synthases

27 July 2018

1 reference

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Mechanisms of platelet activation: thromboxane A2 as an amplifying signal for other agonists

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186390

Acetylation of prostaglandin synthase by aspirin

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186390

Serum aspirin esterase is strongly associated with glucose and lipids in healthy subjects: different association patterns in subjects with type 2 diabetes mellitus

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186390

Increased blood plasma hydrolysis of acetylsalicylic acid in type 2 diabetic patients: a role of plasma esterases

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186390

Red blood cells highly express type I platelet-activating factor-acetylhydrolase (PAF-AH) which consists of the alpha1/alpha2 complex

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186390

Distinguishing phospholipase A2 types in biological samples by employing group-specific assays in the presence of inhibitors

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186390

Postoperative decline in plasma aspirin-esterase and cholinesterase activity in surgical patients.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186390

Effects of salicylates on human platelets.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186390

Absorption kinetics of aspirin in man following oral administration of an aqueous solution

26 September 2018

1 reference

12 December 2020

Platelet-activating factor acetylhydrolase in human erythrocytes

1 reference

12 December 2020

The platelet-activating factor acetylhydrolase from human erythrocytes. Purification and properties

1 reference

12 December 2020

Targeted cyclooxygenase gene (ptgs) exchange reveals discriminant isoform functionality

1 reference

12 December 2020

Aspirin, absorption rate and analgesic effect

1 reference

12 December 2020

The relative roles of hydrolases of the erythrocyte and other tissues in controlling aspirin survival in vivo

1 reference

12 December 2020

Butyrylcholinesterase-catalysed hydrolysis of aspirin, a negatively charged ester, and aspirin-related neutral esters

1 reference

12 December 2020

Dose-dependent aspirin hydrolysis and platelet aggregation in patients with atherosclerosis

1 reference

12 December 2020

Deficiency of plasma platelet-activating factor acetylhydrolase: roles of blood cells

1 reference

12 December 2020

Plasma esterase activity in patients with aspirin-sensitive asthma or urticaria

1 reference

12 December 2020

1 reference

12 December 2020

Identification and partial purification of the major aspirin hydrolyzing enzyme in human blood

1 reference

12 December 2020

Human plasma platelet-activating factor acetylhydrolase. Purification and properties

1 reference

12 December 2020

Intracellular PAF catabolism by PAF acetylhydrolase counteracts continual PAF synthesis

1 reference

12 December 2020

Purification and characterization of bovine brain platelet-activating factor acetylhydrolase

1 reference

12 December 2020

Aspirin survival in human blood modulated by the concentration of erythrocytes

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M111.267161

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7 August 2017

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7 August 2017

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