The trypanocidal activity of amidine compounds does not correlate with their binding affinity to Trypanosoma cruzi kinetoplast DNA (Q35270391)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21807972%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

title

The trypanocidal activity of amidine compounds does not correlate with their binding affinity to Trypanosoma cruzi kinetoplast DNA (English)

1 reference

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9 February 2020

0 references

8

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9 February 2020

Abdelbasset A. Farahat

10

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9 February 2020

author name string

A Daliry

1

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9 February 2020

M Q Pires

2

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9 February 2020

C F Silva

3

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9 February 2020

R S Pacheco

4

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9 February 2020

M Munde

5

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9 February 2020

C E Stephens

6

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9 February 2020

A Kumar

7

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9 February 2020

Z Liu

9

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9 February 2020

S Akay

11

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9 February 2020

P Som

12

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9 February 2020

Q Hu

13

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9 February 2020

D W Boykin

14

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9 February 2020

W D Wilson

15

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9 February 2020

S L De Castro

16

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9 February 2020

M N C Soeiro

17

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9 February 2020

language of work or name

English

0 references

publication date

1 August 2011

1 reference

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Antimicrobial Agents and Chemotherapy

9 February 2020

published in

1 reference

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9 February 2020

volume

55

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9 February 2020

issue

10

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9 February 2020

page(s)

4765-4773

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Arylimidamide DB766, a potential chemotherapeutic candidate for Chagas' disease treatment

9 February 2020

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Efficacy of the novel diamidine compound 2,5-Bis(4-amidinophenyl)- furan-bis-O-Methlylamidoxime (Pafuramidine, DB289) against Trypanosoma brucei rhodesiense infection in vervet monkeys after oral administration

27 July 2018

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Pentamidine binds to tRNA through non-specific hydrophobic interactions and inhibits aminoacylation and translation

27 July 2018

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The mitochondrion is a site of trypanocidal action of the aromatic diamidine DB75 in bloodstream forms of Trypanosoma brucei

27 July 2018

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Sequence and length dependent thermodynamic differences in heterocyclic diamidine interactions at AT base pairs in the DNA minor groove

27 July 2018

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Cellular effects of reversed amidines on Trypanosoma cruzi

27 July 2018

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Diphenyl furans and aza analogs: effects of structural modification on in vitro activity, DNA binding, and accumulation and distribution in trypanosomes

27 July 2018

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Binding of the universal minicircle sequence binding protein at the kinetoplast DNA replication origin.

27 July 2018

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Fellowship of the rings: the replication of kinetoplast DNA.

27 July 2018

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Mitochondrial proteins and complexes in Leishmania and Trypanosoma involved in U-insertion/deletion RNA editing

27 July 2018

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TbMP44 is essential for RNA editing and structural integrity of the editosome in Trypanosoma brucei

27 July 2018

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Uridine insertion/deletion RNA editing in trypanosome mitochondria--a review

27 July 2018

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The structure and replication of kinetoplast DNA

27 July 2018

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Strains and clones of Trypanosoma cruzi can be characterized by pattern of restriction endonuclease products of kinetoplast DNA minicircles

27 July 2018

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Isolation of the Kinetoplast DNA ofLeishmania tarentolaein the Form of a Network*

27 July 2018

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Nucleotide sequence of a Trypanosoma cruzi minicircle

27 July 2018

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Peculiar sequence organization of kinetoplast DNA minicircles from Trypanosoma cruzi.

27 July 2018

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Kinetoplast DNA minicircles: high-copy-number mitochondrial plasmids

27 July 2018

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Conserved sequence blocks in kinetoplast minicircles from diverse species of trypanosomes

27 July 2018

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Synthesis and antiprotozoal activity of 2,5-bis(4-guanylphenyl)furans

27 July 2018

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Novel arylimidamides for treatment of visceral leishmaniasis

27 July 2018

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In vitro analyses of the effect of aromatic diamidines upon Trypanosoma cruzi

26 September 2018

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Trypanosoma cruzi: activity of heterocyclic cationic molecules in vitro

26 September 2018

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Inhibition by Dications of in vitro growth of Leishmania major and Leishmania tropica: causative agents of old world cutaneous leishmaniasis

26 September 2018

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26 September 2018

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Trypanocidal activity of the phenyl-substituted analogue of furamidine DB569 against Trypanosoma cruzi infection in vivo

26 September 2018

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26 September 2018

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Phenyl substitution of furamidine markedly potentiates its anti-parasitic activity against Trypanosoma cruzi and Leishmania amazonensis

26 September 2018

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Synthesis and antiprotozoal activity of aza-analogues of furamidine

26 September 2018

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The activity of diguanidino and 'reversed' diamidino 2,5-diarylfurans versus Trypanosoma cruzi and Leishmania donovani

26 September 2018

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Diguanidino and "reversed" diamidino 2,5-diarylfurans as antimicrobial agents

26 September 2018

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Pentamidine is an uncoupler of oxidative phosphorylation in rat liver mitochondria

26 September 2018

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Trypanocidal activity and selectivity in vitro of aromatic amidine compounds upon bloodstream and intracellular forms of Trypanosoma cruzi

26 September 2018

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GROWTH AND DIFFERENTIATION IN TRYPANOSOMA CRUZI. I. ORIGIN OF METACYCLIC TRYPANOSOMES IN LIQUID MEDIA

8 December 2018

1 reference

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Chagas' disease and HIV co-infection: genotypic characterization of the Trypanosoma cruzi strain

8 December 2018

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The biological in vitro effect and selectivity of aromatic dicationic compounds on Trypanosoma cruzi

8 December 2018

1 reference

12 December 2020

Interaction of Trypanosoma cruzi with macrophages in vitro: dissociation of the attachment and internalization phases by low temperature and cytochalasin B

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12 December 2020

Population heterogeneity among clones of New World Leishmania species

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12 December 2020

Trypanosoma cruzi targets for new chemotherapeutic approaches

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12 December 2020

Identifiers

DOI

10.1128/AAC.00229-11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21807972%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21807972%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

PubMed publication ID

21807972

1 reference