Nucleotide exchange in dimeric MCAK induces longitudinal and lateral stress at microtubule ends to support depolymerization. (Q35278789)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25066134%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

title

Nucleotide exchange in dimeric MCAK induces longitudinal and lateral stress at microtubule ends to support depolymerization (English)

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10 March 2020

3

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10 March 2020

author name string

Kyle M Burns

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25066134%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Mike Wagenbach

series ordinal

2

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10 March 2020

David C Schriemer

series ordinal

4

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10 March 2020

publication date

24 July 2014

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10 March 2020

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10 March 2020

volume

22

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10 March 2020

issue

8

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10 March 2020

page(s)

1173-1183

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Aurora B inhibits MCAK activity through a phosphoconformational switch that reduces microtubule association

10 March 2020

cites work

1 reference

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A second tubulin binding site on the kinesin-13 motor head domain is important during mitosis

12 July 2018

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Lateral to end-on conversion of chromosome-microtubule attachment requires kinesins CENP-E and MCAK

12 July 2018

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Structural model for tubulin recognition and deformation by kinesin-13 microtubule depolymerases

12 July 2018

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Platform dependencies in bottom-up hydrogen/deuterium exchange mass spectrometry

12 July 2018

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Kinesin-13 and tubulin posttranslational modifications regulate microtubule growth in axon regeneration

12 July 2018

1 reference

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The kinesin-13 MCAK has an unconventional ATPase cycle adapted for microtubule depolymerization.

12 July 2018

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Centriolar kinesin Kif24 interacts with CP110 to remodel microtubules and regulate ciliogenesis

12 July 2018

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Performance characteristics of a new hybrid quadrupole time-of-flight tandem mass spectrometer (TripleTOF 5600).

12 July 2018

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Discovery and characterization of the laulimalide-microtubule binding mode by mass shift perturbation mapping

12 July 2018

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I-TASSER: a unified platform for automated protein structure and function prediction

12 July 2018

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Catalysis of the microtubule on-rate is the major parameter regulating the depolymerase activity of MCAK.

12 July 2018

1 reference

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Interplay of microtubule dynamics and sliding during bipolar spindle formation in mammalian cells

12 July 2018

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An EB1-binding motif acts as a microtubule tip localization signal

12 July 2018

1 reference

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Structural mass spectrometry of the alpha beta-tubulin dimer supports a revised model of microtubule assembly

12 July 2018

1 reference

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A new model for binding of kinesin 13 to curved microtubule protofilaments

12 July 2018

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Structure of the Kinesin13-Microtubule Ring Complex

12 July 2018

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Studying microtubules by electron microscopy

12 July 2018

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A unique mode of microtubule stabilization induced by peloruside A

12 July 2018

1 reference

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I-TASSER server for protein 3D structure prediction

12 July 2018

1 reference

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The kinesin-13 proteins Kif2a, Kif2b, and Kif2c/MCAK have distinct roles during mitosis in human cells.

12 July 2018

1 reference

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The interplay of the N- and C-terminal domains of MCAK control microtubule depolymerization activity and spindle assembly

12 July 2018

1 reference

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Kinesin-13s form rings around microtubules

12 July 2018

1 reference

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Plus end-specific depolymerase activity of Kip3, a kinesin-8 protein, explains its role in positioning the yeast mitotic spindle

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386277

The depolymerizing kinesin MCAK uses lattice diffusion to rapidly target microtubule ends

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386277

Quantitating the statistical distribution of deuterium incorporation to extend the utility of H/D exchange MS data

12 July 2018

1 reference

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Full-length dimeric MCAK is a more efficient microtubule depolymerase than minimal domain monomeric MCAK

12 July 2018

1 reference

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MCAK associates with the tips of polymerizing microtubules

12 July 2018

1 reference

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MCAK, a Kin I kinesin, increases the catastrophe frequency of steady-state HeLa cell microtubules in an ATP-dependent manner in vitro

12 July 2018

1 reference

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The KinI kinesin Kif2a is required for bipolar spindle assembly through a functional relationship with MCAK

12 July 2018

1 reference

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C-terminus of mitotic centromere-associated kinesin (MCAK) inhibits its lattice-stimulated ATPase activity

12 July 2018

1 reference

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A common mechanism for microtubule destabilizers-M type kinesins stabilize curling of the protofilament using the class-specific neck and loops

12 July 2018

1 reference

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K-loop insertion restores microtubule depolymerizing activity of a "neckless" MCAK mutant

12 July 2018

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12 July 2018

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Refined structure of alpha beta-tubulin at 3.5 A resolution

12 July 2018

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Molecular dissection of the microtubule depolymerizing activity of mitotic centromere-associated kinesin

12 July 2018

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Sequence complexity of disordered protein

12 July 2018

1 reference

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Single-molecule analysis of kinesin motility reveals regulation by the cargo-binding tail domain

12 July 2018

1 reference

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Mitotic centromere-associated kinesin is important for anaphase chromosome segregation

12 July 2018

1 reference

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The design plan of kinesin motors

12 July 2018

1 reference

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Yeast Kar3 is a minus-end microtubule motor protein that destabilizes microtubules preferentially at the minus ends.

12 July 2018

1 reference

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Nepenthesin from monkey cups for hydrogen/deuterium exchange mass spectrometry

12 July 2018

1 reference

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The role of the kinesin-13 neck in microtubule depolymerization.

26 September 2018

1 reference

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The microtubule-destabilizing kinesin XKCM1 is required for chromosome positioning during spindle assembly

26 September 2018

1 reference

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A mechanism for microtubule depolymerization by KinI kinesins

26 September 2018

1 reference

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Kinesin's IAK tail domain inhibits initial microtubule-stimulated ADP release.

26 September 2018

1 reference

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Sequence Data Analysis for Long Disordered Regions Prediction in the Calcineurin Family

26 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25066134

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Predicting Protein Disorder for N-, C-, and Internal Regions

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25066134

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.STR.2014.06.010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25066134%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25066134%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

PubMed publication ID

25066134

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25066134%20AND%20SRC:MED&resulttype=core&format=json