Intracerebroventricular administration of HIV-1 Tat induces brain cytokine and indoleamine 2,3-dioxygenase expression: a possible mechanism for AIDS comorbid depression. (Q35317241)

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English	Intracerebroventricular administration of HIV-1 Tat induces brain cytokine and indoleamine 2,3-dioxygenase expression: a possible mechanism for AIDS comorbid depression.	scientific article

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2 February 2020

Intracerebroventricular administration of HIV-1 Tat induces brain cytokine and indoleamine 2,3-dioxygenase expression: a possible mechanism for AIDS comorbid depression (English)

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2 February 2020

Keith W. Kelley

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2 February 2020

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Marcus A Lawson

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17 May 2011

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2 February 2020

Brain, Behavior, and Immunity

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1569-1575

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2 February 2020

Central administration of lipopolysaccharide induces depressive-like behavior in vivo and activates brain indoleamine 2,3 dioxygenase in murine organotypic hippocampal slice cultures

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27 July 2018

Molecular Mechanisms of Neurodegenerative Diseases Induced by Human Retroviruses: A Review

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27 July 2018

LPS-induced indoleamine 2,3-dioxygenase is regulated in an interferon-gamma-independent manner by a JNK signaling pathway in primary murine microglia

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27 July 2018

Role of Tat protein in HIV neuropathogenesis

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27 July 2018

Interferon-gamma and tumor necrosis factor-alpha mediate the upregulation of indoleamine 2,3-dioxygenase and the induction of depressive-like behavior in mice in response to bacillus Calmette-Guerin

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27 July 2018

Differential regulation of indoleamine-2,3-dioxygenase (IDO) by HIV type 1 clade B and C Tat protein

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27 July 2018

Induction of IDO by bacille Calmette-Guérin is responsible for development of murine depressive-like behavior

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27 July 2018

Spatio-temporal differences in the profile of murine brain expression of proinflammatory cytokines and indoleamine 2,3-dioxygenase in response to peripheral lipopolysaccharide administration.

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27 July 2018

Lipopolysaccharide-induced depressive-like behavior is mediated by indoleamine 2,3-dioxygenase activation in mice.

1 reference

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27 July 2018

Aging sensitizes mice to behavioral deficits induced by central HIV-1 gp120

1 reference

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27 July 2018

Review of treatment studies of depression in HIV.

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27 July 2018

HIV-1 infection and AIDS: consequences for the central nervous system

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27 July 2018

Astrocyte activation and dysfunction and neuron death by HIV-1 Tat expression in astrocytes

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27 July 2018

Intracellular human immunodeficiency virus Tat expression in astrocytes promotes astrocyte survival but induces potent neurotoxicity at distant sites via axonal transport

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27 July 2018

Intracerebral HIV-1 glycoprotein 120 produces sickness behavior and pituitary-adrenal activation in rats: role of prostaglandins.

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27 July 2018

Further evidence for the depressive effects of cytokines: anhedonia and neurochemical changes

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27 July 2018

Cytokine-induced sickness behavior: where do we stand?

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27 July 2018

Fluoro-Jade B: a high affinity fluorescent marker for the localization of neuronal degeneration

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27 July 2018

Molecular pathway involved in HIV-1-induced CNS pathology: role of viral regulatory protein, Tat.

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27 July 2018

HIV-1 tat molecular diversity and induction of TNF-alpha: implications for HIV-induced neurological disease

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27 July 2018

Sources of the neurotoxin quinolinic acid in the brain of HIV-1-infected patients and retrovirus-infected macaques

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27 July 2018

Cellular immune activation in the brain and human immunodeficiency virus infection

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27 July 2018

Tryptophan degradation in patients infected by human immunodeficiency virus

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27 July 2018

Reduction of sucrose preference by chronic unpredictable mild stress, and its restoration by a tricyclic antidepressant

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27 July 2018

Cerebrospinal fluid quinolinic acid concentrations are increased in acquired immune deficiency syndrome

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27 July 2018

HIV-1, macrophages, glial cells, and cytokines in AIDS nervous system disease

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27 July 2018

Quinolinic acid in cerebrospinal fluid and serum in HIV-1 infection: relationship to clinical and neurological status

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27 July 2018

Inter-relationships between quinolinic acid, neuroactive kynurenines, neopterin and beta 2-microglobulin in cerebrospinal fluid and serum of HIV-1-infected patients

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27 July 2018

Behavioral despair in mice: a primary screening test for antidepressants

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27 July 2018

Stress and IL-1beta contribute to the development of depressive-like behavior following peripheral nerve injury

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26 September 2018

Modulation of indoleamine-2,3-dioxygenase expression and activity by HIV-1 in human macrophages

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26 September 2018

Minocycline attenuates lipopolysaccharide (LPS)-induced neuroinflammation, sickness behavior, and anhedonia.

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26 September 2018

Rodent models of depression: forced swimming and tail suspension behavioral despair tests in rats and mice.

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26 September 2018

From inflammation to sickness and depression: when the immune system subjugates the brain

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26 September 2018

Cell death in HIV dementia

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26 September 2018

Proinflammatory synergism of ethanol and HIV-1 Tat protein in brain tissue

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26 September 2018

HIV-1 tat protein upregulates inflammatory mediators and induces monocyte invasion into the brain

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26 September 2018

Synaptic transport of human immunodeficiency virus-Tat protein causes neurotoxicity and gliosis in rat brain.

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Neuropathologies in Transgenic Mice Expressing Human Immunodeficiency Virus Type 1 Tat Protein under the Regulation of the Astrocyte-Specific Glial Fibrillary Acidic Protein Promoter and Doxycycline

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26 September 2018

Involvement of brain cytokines in the neurobehavioral disturbances induced by HIV-1 glycoprotein120.

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26 September 2018

Human immunodeficiency virus type-1 Tat protein induces nuclear factor (NF)-kappaB activation and oxidative stress in microglial cultures by independent mechanisms.

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26 September 2018

Quinolinic acid is produced by macrophages stimulated by platelet activating factor, Nef and Tat.

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26 September 2018

Lipopolysaccharide induction of indoleamine 2,3-dioxygenase is mediated dominantly by an IFN-gamma-independent mechanism

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26 September 2018

Human primary CD4 + T cells activated in the presence of IFN-alpha 2b express functional indoleamine 2,3-dioxygenase

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26 September 2018

Pathways to neuronal injury and apoptosis in HIV-associated dementia.

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26 September 2018

The signal transducer and activator of transcription 1alpha and interferon regulatory factor 1 are not essential for the induction of indoleamine 2,3-dioxygenase by lipopolysaccharide: involvement of p38 mitogen-activated protein kinase and nuclear

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The neuropathogenesis of HIV-1 infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/21620953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decreased serum tryptophan in patients with HIV-1 infection correlates with increased serum neopterin and with neurologic/psychiatric symptoms

1 reference

https://pubmed.ncbi.nlm.nih.gov/21620953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.BBI.2011.05.006

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2 February 2020

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2 February 2020

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2 February 2020

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