Mutational spectrum analysis of chronic myelomonocytic leukemia includes genes associated with epigenetic regulation: UTX, EZH2, and DNMT3A. (Q35346433)

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9 February 2020

title

Mutational spectrum analysis of chronic myelomonocytic leukemia includes genes associated with epigenetic regulation: UTX, EZH2, and DNMT3A (English)

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chronic myelomonocytic leukemia

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5

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Fabiola Traina

6

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Alan F List

12

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Anjana Rao

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author name string

Anna M Jankowska

1

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Hideki Makishima

2

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Ramon V Tiu

3

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Hadrian Szpurka

4

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Valeria Visconte

7

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Yuka Sugimoto

8

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Courtney Prince

9

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Christine O'Keefe

10

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Eric D Hsi

11

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Mikkael A Sekeres

13

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Michael A McDevitt

15

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Jaroslaw P Maciejewski

16

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9 February 2020

language of work or name

English

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publication date

9 August 2011

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9 February 2020

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9 February 2020

volume

118

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issue

14

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page(s)

3932-3941

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Prognostic impact of SNP array karyotyping in myelodysplastic syndromes and related myeloid malignancies

9 February 2020

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DNMT3A Mutations in Acute Myeloid Leukemia

12 July 2018

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12 July 2018

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12 July 2018

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Somatic mutations of the histone methyltransferase gene EZH2 in myelodysplastic syndromes

12 July 2018

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12 July 2018

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Significance of JAK2 and TET2 mutations in myelodysplastic syndromes

12 July 2018

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Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

12 July 2018

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Mutations of e3 ubiquitin ligase cbl family members constitute a novel common pathogenic lesion in myeloid malignancies.

12 July 2018

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ASXL1 represses retinoic acid receptor-mediated transcription through associating with HP1 and LSD1

12 July 2018

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Loss-of-function Additional sex combs like 1 mutations disrupt hematopoiesis but do not cause severe myelodysplasia or leukemia

12 July 2018

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TET2 gene mutation is a frequent and adverse event in chronic myelomonocytic leukemia

12 July 2018

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Recurring mutations found by sequencing an acute myeloid leukemia genome

12 July 2018

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Acquired mutations in TET2 are common in myelodysplastic syndromes

12 July 2018

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Mutation in TET2 in myeloid cancers

12 July 2018

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Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1

12 July 2018

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Loss of heterozygosity 4q24 and TET2 mutations associated with myelodysplastic/myeloproliferative neoplasms

12 July 2018

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12 July 2018

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Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer

12 July 2018

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12 July 2018

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High-throughput sequencing screen reveals novel, transforming RAS mutations in myeloid leukemia patients

12 July 2018

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Genome profiling of chronic myelomonocytic leukemia: frequent alterations of RAS and RUNX1 genes

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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26 September 2018

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26 September 2018

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26 September 2018

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Mutations of polycomb-associated gene ASXL1 in myelodysplastic syndromes and chronic myelomonocytic leukaemia.

26 September 2018

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Frequent CBL mutations associated with 11q acquired uniparental disomy in myeloproliferative neoplasms

26 September 2018

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RUNX1 mutations are frequent in chronic myelomonocytic leukemia and mutations at the C-terminal region might predict acute myeloid leukemia transformation.

26 September 2018

1 reference

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250K single nucleotide polymorphism array karyotyping identifies acquired uniparental disomy and homozygous mutations, including novel missense substitutions of c-Cbl, in myeloid malignancies

26 September 2018

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Activity of STI571 in chronic myelomonocytic leukemia with a platelet-derived growth factor beta receptor fusion oncogene

26 September 2018

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Next-Generation Sequencing Technology Reveals a Characteristic Pattern of Molecular Mutations in 72.8% of Chronic Myelomonocytic Leukemia by Detecting Frequent Alterations in TET2, CBL, RAS, and RUNX1

26 September 2018

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Novel homo- and hemizygous mutations in EZH2 in myeloid malignancies

8 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21828135

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

ASXL1 mutation is associated with poor prognosis and acute transformation in chronic myelomonocytic leukaemia

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21828135

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Overexpression of the EZH2, RING1 and BMI1 genes is common in myelodysplastic syndromes: relation to adverse epigenetic alteration and poor prognostic scoring

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21828135

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1182/BLOOD-2010-10-311019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21828135%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21828135%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

PubMed publication ID

21828135

1 reference