Direct genetic demonstration of G alpha 13 coupling to the orphan G protein-coupled receptor G2A leading to RhoA-dependent actin rearrangement. (Q35384122)

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English	Direct genetic demonstration of G alpha 13 coupling to the orphan G protein-coupled receptor G2A leading to RhoA-dependent actin rearrangement.	scientific article

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scholarly article

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1 November 2019

Direct genetic demonstration of G alpha 13 coupling to the orphan G protein-coupled receptor G2A leading to RhoA-dependent actin rearrangement (English)

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1 November 2019

G protein-coupled receptor

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3

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1 November 2019

author name string

J H Kabarowski

1

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J D Feramisco

2

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J L Gu

4

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1 November 2019

S W Luoh

5

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1 November 2019

M I Simon

6

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O N Witte

7

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1 October 2000

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6

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Proceedings of the National Academy of Sciences of the United States of America

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97

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22

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12109-12114

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1 November 2019

G2A is an oncogenic G protein-coupled receptor

1 reference

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Using green fluorescent proteins to study G-protein-coupled receptor localization and trafficking

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Searching for significance in TCR-cytoskeleton interactions

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Rac downregulates Rho activity: reciprocal balance between both GTPases determines cellular morphology and migratory behavior

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EPS8 and E3B1 transduce signals from Ras to Rac

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ADP-ribosylation of rho by C3 ribosyltransferase inhibits IL-2 production and sustained calcium influx in activated T cells.

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12 July 2018

Integrin signaling

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Regulators of G protein signaling exhibit distinct patterns of gene expression and target G protein specificity in human lymphocytes

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Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton

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Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes

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A DNA damage and stress inducible G protein-coupled receptor blocks cells in G2/M

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Specific involvement of G proteins in regulation of serum response factor-mediated gene transcription by different receptors

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Signals from Ras and Rho GTPases interact to regulate expression of p21Waf1/Cip1.

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Cloning, characterization, and mapping of human homolog of mouse T-cell death-associated gene

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12 July 2018

Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13

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12 July 2018

Vascular system defects and impaired cell chemokinesis as a result of Galpha13 deficiency

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12 July 2018

A role for Rho in Ras transformation

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12 July 2018

The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain

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Specificity of receptor-G protein interactions: searching for the structure behind the signal.

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12 July 2018

Proteins regulating Ras and its relatives

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12 July 2018

Activated mutant of G alpha 13 induces Egr-1, c-fos, and transformation in NIH 3T3 cells.

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12 July 2018

Structure and functional analysis of G protein-coupled receptors and potential diagnostic ligands.

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12 July 2018

An essential role for Rho, Rac, and Cdc42 GTPases in cell cycle progression through G1

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12 July 2018

The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF

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12 July 2018

Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation

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12 July 2018

Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

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12 July 2018

The RhoA-dependent assembly of focal adhesions in Swiss 3T3 cells is associated with increased tyrosine phosphorylation and the recruitment of both pp125FAK and protein kinase C-delta to focal adhesions.

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G alpha 12 and G alpha 13 subunits define a fourth class of G protein alpha subunits

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12 July 2018

25 Identification of receptor-activated G proteins with photoreactive GTP analog, α-32PGTP azidoanilide

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12 July 2018

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12 July 2018

The G-protein G13 but not G12 mediates signaling from lysophosphatidic acid receptor via epidermal growth factor receptor to Rho.

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26 September 2018

Defective platelet activation in G alpha(q)-deficient mice.

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Identifiers

10.1073/PNAS.97.22.12109

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1 November 2019

2000PNAS...9712109K

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1 November 2019

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