Mechanisms of atrial-selective block of Na⁺ channels by ranolazine: II. Insights from a mathematical model (Q35396014)

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9 February 2020

title

Mechanisms of atrial-selective block of Na⁺ channels by ranolazine: II. Insights from a mathematical model (English)

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9 February 2020

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5

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9 February 2020

Charles Antzelevitch

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9 February 2020

author name string

Vladislav V Nesterenko

1

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9 February 2020

Andrew C Zygmunt

2

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9 February 2020

Sridharan Rajamani

3

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9 February 2020

Luiz Belardinelli

4

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9 February 2020

publication date

5 August 2011

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American Journal of Physiology Heart and Circulatory Physiology

9 February 2020

published in

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9 February 2020

volume

301

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9 February 2020

issue

4

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9 February 2020

page(s)

H1615-24

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Mechanisms of atrial-selective block of Na⁺ channels by ranolazine: I. Experimental analysis of the use-dependent block

9 February 2020

cites work

1 reference

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Use-dependent block of cardiac late Na(+) current by ranolazine

12 July 2018

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Atrial-selective sodium channel block as a novel strategy for the management of atrial fibrillation

12 July 2018

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New pharmacological strategies for the treatment of atrial fibrillation

12 July 2018

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Atrial-selective effects of chronic amiodarone in the management of atrial fibrillation.

12 July 2018

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State- and use-dependent block of muscle Nav1.4 and neuronal Nav1.7 voltage-gated Na+ channel isoforms by ranolazine

12 July 2018

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Outward stabilization of the S4 segments in domains III and IV enhances lidocaine block of sodium channels

12 July 2018

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Ranolazine improves abnormal repolarization and contraction in left ventricular myocytes of dogs with heart failure by inhibiting late sodium current

12 July 2018

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State-dependent block of human cardiac hNav1.5 sodium channels by propafenone

12 July 2018

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Block of inactivation-deficient Na+ channels by local anesthetics in stably transfected mammalian cells: evidence for drug binding along the activation pathway

12 July 2018

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Electrophysiological effects of ranolazine, a novel antianginal agent with antiarrhythmic properties

12 July 2018

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Tryptophan scanning of D1S6 and D4S6 C-termini in voltage-gated sodium channels

12 July 2018

1 reference

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Molecular action of lidocaine on the voltage sensors of sodium channels

12 July 2018

1 reference

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Channel openings are necessary but not sufficient for use-dependent block of cardiac Na(+) channels by flecainide: evidence from the analysis of disease-linked mutations

12 July 2018

1 reference

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Temperature dependence of early and late currents in human cardiac wild-type and long Q-T DeltaKPQ Na+ channels.

12 July 2018

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Phasic ion channel blockade. A kinetic model and parameter estimation procedure.

12 July 2018

1 reference

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Lidocaine blockade of continuously and transiently accessible sites in cardiac sodium channels*1

12 July 2018

1 reference

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Atrium-selective sodium channel block as a strategy for suppression of atrial fibrillation: differences in sodium channel inactivation between atria and ventricles and the role of ranolazine

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3197376

10.1152/AJPHEART.00243.2011

26 September 2018

Identifiers

DOI

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9 February 2020

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9 February 2020

PubMed publication ID

21821780

1 reference