Phase I and pharmacokinetic study of COL-3 in patients with recurrent high-grade gliomas (Q35403440)

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30 January 2020

title

Phase I and pharmacokinetic study of COL-3 in patients with recurrent high-grade gliomas (English)

1 reference

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30 January 2020

1 reference

6

1 reference

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30 January 2020

7

Steven Piantadosi

1 reference

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30 January 2020

3

Tom Mikkelsen

1 reference

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30 January 2020

author name string

Michelle A Rudek

1

1 reference

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30 January 2020

Pamela New

2

1 reference

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30 January 2020

Surasak Phuphanich

4

1 reference

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30 January 2020

Jane B Alavi

5

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30 January 2020

Joy D Fisher

8

1 reference

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30 January 2020

Stuart A Grossman

9

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publication date

6 May 2011

1 reference

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Journal of Neuro-Oncology

30 January 2020

published in

1 reference

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volume

105

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30 January 2020

issue

2

1 reference

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30 January 2020

page(s)

375-381

1 reference

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Anti-invasive and antiangiogenic effects of MMI-166 on malignant glioma cells

30 January 2020

cites work

1 reference

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Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma

12 July 2018

1 reference

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A phase I and pharmacokinetic study of Col-3 (Metastat), an oral tetracycline derivative with potent matrix metalloproteinase and antitumor properties

12 July 2018

1 reference

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Upregulation of tissue inhibitor of metalloproteinases (TIMP)-2 promotes matrix metalloproteinase (MMP)-2 activation and cell invasion in a human glioblastoma cell line

12 July 2018

1 reference

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Drug-induced lupus associated with COL-3: report of 3 cases

12 July 2018

1 reference

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Phase I clinical trial of oral COL-3, a matrix metalloproteinase inhibitor, in patients with refractory metastatic cancer

12 July 2018

1 reference

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Development of matrix metalloproteinase inhibitors in cancer therapy.

12 July 2018

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A mechanistic approach to antiepileptic drug interactions

12 July 2018

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Tetracyclines Inhibit Connective Tissue Breakdown: New Therapeutic Implications for an Old Family of Drugs

12 July 2018

1 reference

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Gelatinase A expression in human malignant gliomas.

12 July 2018

1 reference

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Specific matrix metalloproteinase profiles in the cerebrospinal fluid correlated with the presence of malignant astrocytomas, brain metastases, and carcinomatous meningitis

21 January 2018

1 reference

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Expression of matrix metalloproteinases and their inhibitors in human brain tumors.

21 January 2018

1 reference

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Expression and localization of 72 kDa type IV collagenase (MMP-2) in human malignant gliomas in vivo.

21 January 2018

1 reference

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The expression of matrix metalloproteinase-2 and -9 in human gliomas of different pathological grades.

21 January 2018

1 reference

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Effect of synthetic matrix-metalloproteinase inhibitors on invasive capacity and proliferation of human malignant gliomas in vitro.

21 January 2018

1 reference

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Matrix metalloproteinase inhibitor COL-3 in the treatment of AIDS-related Kaposi's sarcoma: a phase I AIDS malignancy consortium study

21 January 2018

1 reference

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A sensitive method for determination of COL-3, a chemically modified tetracycline, in human plasma using high-performance liquid chromatography and ultraviolet detection

21 January 2018

1 reference

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Factors Involved in the Pharmacokinetics of COL‐3, a Matrix Metalloproteinase Inhibitor, in Patients with Refractory Metastatic Cancer: Clinical and Experimental Studies

21 January 2018

1 reference

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Significant intestinal excretion, one source of variability in pharmacokinetics of COL-3, a chemically modified tetracycline

21 January 2018

1 reference

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Phase II trial of temozolomide plus marimastat for recurrent anaplastic gliomas: a relationship among efficacy, joint toxicity and anticonvulsant status

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0602-9

Phase II trial of temozolomide plus the matrix metalloproteinase inhibitor, marimastat, in recurrent and progressive glioblastoma multiforme

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0602-9

Phase I clinical and pharmacokinetic study of irinotecan in adults with recurrent malignant glioma

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3197967

Evidence for dissolution rate-limited absorption of COL-3, a matrix metalloproteinase inhibitor, leading to the irregular absorption profile in rats after oral administration

26 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21547395

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The expression of UDP-glucuronosyltransferases of the UGT1 family in human liver and kidney and in response to drugs

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21547395

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A phase II and pharmacological study of the matrix metalloproteinase inhibitor (MMPI) COL-3 in patients with advanced soft tissue sarcomas

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21547395

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S11060-011-0602-9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21547395%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

1 reference

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30 January 2020

PubMed publication ID

21547395

1 reference