Rational truncation of an RNA aptamer to prostate-specific membrane antigen using computational structural modeling. (Q35413768)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22004414%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

title

Rational truncation of an RNA aptamer to prostate-specific membrane antigen using computational structural modeling (English)

1 reference

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14 January 2020

1

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14 January 2020

Frank J Hernandez

2

1 reference

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14 January 2020

James O McNamara

10

1 reference

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14 January 2020

Shi-Jie Chen

12

1 reference

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14 January 2020

author name string

Sheng-You Huang

3

1 reference

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14 January 2020

Song Cao

4

1 reference

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14 January 2020

Craig A Howell

5

1 reference

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14 January 2020

Gregory S Thomas

6

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14 January 2020

Xiu Ying Liu

7

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14 January 2020

Natalia Lapteva

8

1 reference

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14 January 2020

David M Spencer

9

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14 January 2020

Xiaoqin Zou

11

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14 January 2020

Paloma H Giangrande

13

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14 January 2020

publication date

1 October 2011

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Nucleic Acid Therapeutics

14 January 2020

published in

1 reference

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14 January 2020

volume

21

1 reference

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14 January 2020

issue

5

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14 January 2020

page(s)

299-314

1 reference

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Physics-based de novo prediction of RNA 3D structures.

14 January 2020

cites work

1 reference

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An aptamer-siRNA chimera suppresses HIV-1 viral loads and protects from helper CD4(+) T cell decline in humanized mice

12 July 2018

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Targeted delivery of a cisplatin prodrug for safer and more effective prostate cancer therapy in vivo

12 July 2018

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Structural prediction and binding analysis of hybridized aptamers

12 July 2018

1 reference

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Folding kinetics for the conformational switch between alternative RNA structures

12 July 2018

1 reference

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MDockPP: A hierarchical approach for protein-protein docking and its application to CAPRI rounds 15-19

12 July 2018

1 reference

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Induction of tumour immunity by targeted inhibition of nonsense-mediated mRNA decay

12 July 2018

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AS-1411, a guanosine-rich oligonucleotide aptamer targeting nucleolin for the potential treatment of cancer, including acute myeloid leukemia.

12 July 2018

1 reference

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Coagulation factor IXa as a target for treatment and prophylaxis of venous thromboembolism

12 July 2018

1 reference

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Dependence of aptamer activity on opposed terminal extensions: improvement of light-regulation efficiency

12 July 2018

1 reference

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Aptamers as a model for functional evaluation of LNA and 2'-amino LNA.

12 July 2018

1 reference

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Expression of prostate-specific membrane antigen (PSMA), increases cell folate uptake and proliferation and suggests a novel role for PSMA in the uptake of the non-polyglutamated folate, folic acid

12 July 2018

1 reference

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Systemic administration of optimized aptamer-siRNA chimeras promotes regression of PSMA-expressing tumors.

12 July 2018

1 reference

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Therapeutic applications of DNA and RNA aptamers.

12 July 2018

1 reference

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Reversible cell-specific drug delivery with aptamer-functionalized liposomes

12 July 2018

1 reference

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ARC-1779, a PEGylated aptamer antagonist of von Willebrand factor for potential use as an anticoagulant or antithrombotic agent

12 July 2018

1 reference

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A new computational approach for mechanical folding kinetics of RNA hairpins.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198747

VARNA: Interactive drawing and editing of the RNA secondary structure

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198747

Prostate-specific membrane antigen targeted imaging and therapy of prostate cancer using a PSMA inhibitor as a homing ligand

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198747

Selection, characterization and application of new RNA HIV gp 120 aptamers for facile delivery of Dicer substrate siRNAs into HIV infected cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198747

The prostate specific membrane antigen regulates the expression of IL-6 and CCL5 in prostate tumour cells by activating the MAPK pathways.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198747

Targeted delivery of cisplatin to prostate cancer cells by aptamer functionalized Pt(IV) prodrug-PLGA-PEG nanoparticles

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198747

RNA folding: conformational statistics, folding kinetics, and ion electrostatics.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198747

Novel dual inhibitory function aptamer-siRNA delivery system for HIV-1 therapy

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198747

RNA secondary structure prediction

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198747

RNA secondary structure analysis using RNAstructure

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198747

Precise engineering of targeted nanoparticles by using self-assembled biointegrated block copolymers.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198747

Post-SELEX chemical optimization of a trypanosome-specific RNA aptamer

12 July 2018

1 reference

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Multivalent 4-1BB binding aptamers costimulate CD8+ T cells and inhibit tumor growth in mice.

12 July 2018

1 reference

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First-in-human evaluation of anti von Willebrand factor therapeutic aptamer ARC1779 in healthy volunteers

12 July 2018

1 reference

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Exploring the sequence space of a DNA aptamer using microarrays

12 July 2018

1 reference

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2'-Deoxy purine, 2'-O-methyl pyrimidine (dRmY) aptamers as candidate therapeutics

12 July 2018

1 reference

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Anti-VEGF aptamer (pegaptanib) therapy for ocular vascular diseases

12 July 2018

1 reference

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First-in-human experience of an antidote-controlled anticoagulant using RNA aptamer technology: a phase 1a pharmacodynamic evaluation of a drug-antidote pair for the controlled regulation of factor IXa activity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198747

Cell type-specific delivery of siRNAs with aptamer-siRNA chimeras

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198747

Aptamer mediated siRNA delivery

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198747

Tumor targeting by an aptamer

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198747

Free energy landscapes of RNA/RNA complexes: with applications to snRNA complexes in spliceosomes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198747

Oligo- and poly-nucleotides: 50 years of chemical synthesis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198747

The Amber biomolecular simulation programs

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198747

Crystal structure of prostate-specific membrane antigen, a tumor marker and peptidase

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198747

Direct in vitro selection of a 2'-O-methyl aptamer to VEGF.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198747

Pharmacokinetics and biodistribution of novel aptamer compositions

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198747

Nanoparticle-aptamer bioconjugates: a new approach for targeting prostate cancer cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198747

RNA aptamers as reversible antagonists of coagulation factor IXa.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198747

Identification and characterization of nuclease-stabilized RNA molecules that bind human prostate cancer cells via the prostate-specific membrane antigen

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198747

Cloning, expression, genomic localization, and enzymatic activities of the mouse homolog of prostate-specific membrane antigen/NAALADase/folate hydrolase

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198747

Generation of a baculovirus recombinant prostate-specific membrane antigen and its use in the development of a novel protein biochip quantitative immunoassay

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198747

Anti-L-selectin aptamers: binding characteristics, pharmacokinetic parameters, and activity against an intravascular target in vivo

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198747

Derivation of RNA aptamer inhibitors of human complement C5.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198747

Efficient synthesis of nucleic acids heavily modified with non-canonical ribose 2'-groups using a mutantT7 RNA polymerase (RNAP).

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198747

Novel approach to specific growth factor inhibition in vivo: antagonism of platelet-derived growth factor in glomerulonephritis by aptamers.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198747

2'-Fluoropyrimidine RNA-based aptamers to the 165-amino acid form of vascular endothelial growth factor (VEGF165). Inhibition of receptor binding and VEGF-induced vascular permeability through interactions requiring the exon 7-encoded domain

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198747

Mechanism of ribose 2'-group discrimination by an RNA polymerase

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198747

Structural probing and damage selection of citrulline- and arginine-specific RNA aptamers identify base positions required for binding

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198747

A double-filter method for nitrocellulose-filter binding: application to protein-nucleic acid interactions

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198747

An RNA motif that binds ATP.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198747

Stability, specific binding activity, and plasma concentration in mice of an oligodeoxynucleotide modified at 5'-terminal with poly(ethylene glycol).

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198747

Potent 2'-amino-2'-deoxypyrimidine RNA inhibitors of basic fibroblast growth factor

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198747

Comprehensive chemical modification interference and nucleotide substitution analysis of an RNA pseudoknot inhibitor to HIV-1 reverse transcriptase

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198747

Modified RNA sequence pools for in vitro selection

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198747

In vitro selection of RNA molecules that bind specific ligands

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198747

Affinity hydrogels for controlled protein release using nucleic acid aptamers and complementary oligonucleotides.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198747

Aptamers as therapeutics.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198747

Characterizing ribonucleases in vitro examples of synergies between biochemical and structural analysis.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198747

Year 2 efficacy results of 2 randomized controlled clinical trials of pegaptanib for neovascular age-related macular degeneration.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198747

Predicting RNA folding thermodynamics with a reduced chain representation model.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198747

Pegaptanib for neovascular age-related macular degeneration

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198747

An aptamer-doxorubicin physical conjugate as a novel targeted drug-delivery platform

26 September 2018

1 reference

12 December 2020

Prostate-specific membrane antigen (PSMA) enzyme activity is elevated in prostate cancer cells

1 reference

12 December 2020

Predicting thermodynamic properties of RNA

1 reference

12 December 2020

Prostate-specific membrane antigen expression in normal and malignant human tissues

1 reference

12 December 2020

An iterative knowledge-based scoring function for protein-protein recognition

1 reference

12 December 2020

Identifiers

DOI

10.1089/NAT.2011.0313

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22004414%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22004414%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

1 reference