GPA: a statistical approach to prioritizing GWAS results by integrating pleiotropy and annotation (Q35418401)

8 August 2017

GPA: a statistical approach to prioritizing GWAS results by integrating pleiotropy and annotation (English)

1 reference

genome-wide association study

8 August 2017

0 references

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1 reference

1 reference

Can Yang

2

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Dongjun Chung

object named as

Dongjun Chung

1

0 references

Joel Gelernter

object named as

Joel Gelernter

4

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author name string

Cong Li

3

1 reference

PubMed ID

25393678

8 August 2017

Hongyu Zhao

5

1 reference

8 August 2017

13 November 2014

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8 August 2017

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8 August 2017

10

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8 August 2017

11

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8 August 2017

e1004787

1 reference

Creative Commons CC0 License

8 August 2017

start time

13 November 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted, dedicated to the public domain by copyright holder

0 references

cites work

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12 July 2018

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Beyond GWASs: illuminating the dark road from association to function

12 July 2018

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Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

12 July 2018

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Pleiotropy in complex traits: challenges and strategies

12 July 2018

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The Genotype-Tissue Expression (GTEx) project

12 July 2018

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Negligible impact of rare autoimmune-locus coding-region variants on missing heritability

12 July 2018

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Improved detection of common variants associated with schizophrenia and bipolar disorder using pleiotropy-informed conditional false discovery rate

12 July 2018

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All SNPs are not created equal: genome-wide association studies reveal a consistent pattern of enrichment among functionally annotated SNPs

12 July 2018

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Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis

12 July 2018

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Improved detection of common variants associated with schizophrenia by leveraging pleiotropy with cardiovascular-disease risk factors

12 July 2018

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Interpreting noncoding genetic variation in complex traits and human disease

12 July 2018

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Annotation of functional variation in personal genomes using RegulomeDB

12 July 2018

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The accessible chromatin landscape of the human genome

12 July 2018

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An integrated encyclopedia of DNA elements in the human genome

12 July 2018

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Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

12 July 2018

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Estimation of pleiotropy between complex diseases using single-nucleotide polymorphism-derived genomic relationships and restricted maximum likelihood

12 July 2018

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Genome-wide efficient mixed-model analysis for association studies

12 July 2018

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Heritability and genetic correlations explained by common SNPs for metabolic syndrome traits

12 July 2018

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Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs.

12 July 2018

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Moving toward System Genetics through Multiple Trait Analysis in Genome-Wide Association Studies

12 July 2018

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Five years of GWAS discovery

12 July 2018

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12 July 2018

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Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4

12 July 2018

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Genome partitioning of genetic variation for complex traits using common SNPs

12 July 2018

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Estimating missing heritability for disease from genome-wide association studies

12 July 2018

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GCTA: a tool for genome-wide complex trait analysis

12 July 2018

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A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci

12 July 2018

1 reference

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Hundreds of variants clustered in genomic loci and biological pathways affect human height

12 July 2018

1 reference

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Accurately assessing the risk of schizophrenia conferred by rare copy-number variation affecting genes with brain function

12 July 2018

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Genomewide association studies and assessment of the risk of disease

12 July 2018

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ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

12 July 2018

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Common SNPs explain a large proportion of the heritability for human height

12 July 2018

1 reference

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Trait-associated SNPs are more likely to be eQTLs: annotation to enhance discovery from GWAS

12 July 2018

1 reference

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Variance component model to account for sample structure in genome-wide association studies

12 July 2018

1 reference

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Prioritizing GWAS results: A review of statistical methods and recommendations for their application

12 July 2018

1 reference

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Finding the missing heritability of complex diseases

12 July 2018

1 reference

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Potential etiologic and functional implications of genome-wide association loci for human diseases and traits

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4230845

Personal genomes: The case of the missing heritability

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4230845

Heritability in the genomics era — concepts and misconceptions

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4230845

Principal components analysis corrects for stratification in genome-wide association studies

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4230845

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4230845

Estimating the occurrence of false positives and false negatives in microarray studies by approximating and partitioning the empirical distribution of p-values

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4230845

Turning of COGS moves forward findings for hormonally mediated cancers.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4230845

FaST linear mixed models for genome-wide association studies

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4230845

Sizing up human height variation

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4230845

Detecting differential gene expression with a semiparametric hierarchical mixture method.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4230845

Association of a tgf-b1-509c/t polymorphism with gastric cancer risk: a meta-analysis

26 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1004787

Microarrays, Empirical Bayes and the Two-Groups Model

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1004787

10.1371/JOURNAL.PGEN.1004787

21 January 2018

Identifiers

DOI

1 reference

8 August 2017

1 reference

8 August 2017

1 reference

PubMed ID

25393678