Predicting immunogenic tumour mutations by combining mass spectrometry and exome sequencing. (Q35453691)

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23 February 2020

title

Predicting immunogenic tumour mutations by combining mass spectrometry and exome sequencing (English)

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23 February 2020

9

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11

Zora Modrusan

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23 February 2020

author name string

Mahesh Yadav

1

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23 February 2020

Suchit Jhunjhunwala

2

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23 February 2020

Qui T Phung

3

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23 February 2020

Patrick Lupardus

4

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23 February 2020

Joshua Tanguay

5

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23 February 2020

Stephanie Bumbaca

6

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23 February 2020

Christian Franci

7

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23 February 2020

Tommy K Cheung

8

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23 February 2020

Toni Weinschenk

10

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23 February 2020

Ira Mellman

12

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23 February 2020

Jennie R Lill

13

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23 February 2020

Lélia Delamarre

14

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language of work or name

English

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publication date

1 November 2014

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23 February 2020

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23 February 2020

volume

515

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issue

7528

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page(s)

572-576

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https://scigraph.springernature.com/pub.10.1038/nature14001

23 February 2020

exact match

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cites work

Functions of the proteasome: from protein degradation and immune surveillance to cancer therapy

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12 December 2020

NetMHC-3.0: accurate web accessible predictions of human, mouse and monkey MHC class I affinities for peptides of length 8-11

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Peptidic termini play a significant role in TCR recognition

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MHC I-associated peptides preferentially derive from transcripts bearing miRNA response elements

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CD8(+) T cells specific for tumor antigens can be rendered dysfunctional by the tumor microenvironment through upregulation of the inhibitory receptors BTLA and PD-1.

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12 December 2020

Fast and SNP-tolerant detection of complex variants and splicing in short reads

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12 December 2020

A framework for variation discovery and genotyping using next-generation DNA sequencing data

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12 December 2020

Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting

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12 December 2020

How TCRs bind MHCs, peptides, and coreceptors

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12 December 2020

PD-1 identifies the patient-specific CD8⁺ tumor-reactive repertoire infiltrating human tumors

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12 December 2020

Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer

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12 December 2020

Neo-antigens predicted by tumor genome meta-analysis correlate with increased patient survival

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12 December 2020

Structural evidence of T cell xeno-reactivity in the absence of molecular mimicry

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12 December 2020

How H13 histocompatibility peptides differing by a single methyl group and lacking conventional MHC binding anchor motifs determine self-nonself discrimination

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12 December 2020

Tumor exome analysis reveals neoantigen-specific T-cell reactivity in an ipilimumab-responsive melanoma

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T cell anergy, exhaustion, senescence, and stemness in the tumor microenvironment

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Oncolytic virus-initiated protective immunity against prostate cancer

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Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection

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12 December 2020

Upregulation of Tim-3 and PD-1 expression is associated with tumor antigen-specific CD8+ T cell dysfunction in melanoma patients

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12 December 2020

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12 December 2020

Oncology meets immunology: the cancer-immunity cycle

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12 December 2020

The three-dimensional structure of H-2Db at 2.4 A resolution: implications for antigen-determinant selection

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12 December 2020

Deriving the consequences of genomic variants with the Ensembl API and SNP Effect Predictor

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12 December 2020

Surveillance of the tumor mutanome by T cells during progression from primary to recurrent ovarian cancer.

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12 December 2020

Affinity thresholds for naive CD8+ CTL activation by peptides and engineered influenza A viruses

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Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules

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12 December 2020

Role of PD-1 in regulating T-cell immunity

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12 December 2020

Exploiting the mutanome for tumor vaccination.

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12 December 2020

Identifiers

DOI

10.1038/NATURE14001

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Dimensions Publication ID

23 February 2020

0 references

1 reference

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