Pausing of RNA polymerase II regulates mammalian developmental potential through control of signaling networks. (Q35470656)

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3 March 2020

title

Pausing of RNA polymerase II regulates mammalian developmental potential through control of signaling networks (English)

1 reference

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Negative elongation factor complex member B

3 March 2020

main subject

1 reference

GOA release 2020-03-11

author

Karen Adelman

9

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3 March 2020

author name string

Lucy H Williams

1

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3 March 2020

George Fromm

2

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3 March 2020

Nolan G Gokey

3

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3 March 2020

Telmo Henriques

4

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3 March 2020

Ginger W Muse

5

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3 March 2020

Adam Burkholder

6

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3 March 2020

David C Fargo

7

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3 March 2020

Guang Hu

8

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3 March 2020

publication date

12 March 2015

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3 March 2020

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3 March 2020

volume

58

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issue

2

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3 March 2020

page(s)

311-322

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Regulatory principles of pluripotency: from the ground state up.

3 March 2020

cites work

1 reference

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Genome-wide dynamics of Pol II elongation and its interplay with promoter proximal pausing, chromatin, and exons

12 July 2018

1 reference

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Erk1/2 activity promotes chromatin features and RNAPII phosphorylation at developmental promoters in mouse ESCs

12 July 2018

1 reference

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Stable pausing by RNA polymerase II provides an opportunity to target and integrate regulatory signals

12 July 2018

1 reference

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Kinetic competition between elongation rate and binding of NELF controls promoter-proximal pausing

12 July 2018

1 reference

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Paused Pol II coordinates tissue morphogenesis in the Drosophila embryo.

12 July 2018

1 reference

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Poised RNA polymerase II changes over developmental time and prepares genes for future expression

12 July 2018

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Promoter-proximal pausing of RNA polymerase II: emerging roles in metazoans

12 July 2018

1 reference

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Regulating the regulators: the pervasive effects of Pol II pausing on stimulus-responsive gene networks

12 July 2018

1 reference

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The transcriptional and epigenomic foundations of ground state pluripotency.

12 July 2018

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Polycomb associates genome-wide with a specific RNA polymerase II variant, and regulates metabolic genes in ESCs

12 July 2018

1 reference

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Paused RNA polymerase II as a developmental checkpoint

12 July 2018

1 reference

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Regulating RNA polymerase pausing and transcription elongation in embryonic stem cells

12 July 2018

1 reference

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Control of the embryonic stem cell state

12 July 2018

1 reference

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Pausing of RNA polymerase II disrupts DNA-specified nucleosome organization to enable precise gene regulation

12 July 2018

1 reference

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The ground state of pluripotency.

12 July 2018

1 reference

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c-Myc regulates transcriptional pause release

12 July 2018

1 reference

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FGF signalling as a mediator of lineage transitions--evidence from embryonic stem cell differentiation

12 July 2018

1 reference

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Global analysis of short RNAs reveals widespread promoter-proximal stalling and arrest of Pol II in Drosophila

12 July 2018

1 reference

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Deconstructing stem cell tumorigenicity: a roadmap to safe regenerative medicine

12 July 2018

1 reference

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Mouse cofactor of BRCA1 (Cobra1) is required for early embryogenesis.

12 July 2018

1 reference

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Nascent RNA sequencing reveals widespread pausing and divergent initiation at human promoters

12 July 2018

1 reference

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Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains

12 July 2018

1 reference

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NELF-mediated stalling of Pol II can enhance gene expression by blocking promoter-proximal nucleosome assembly

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4402150

The ground state of embryonic stem cell self-renewal

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4402150

RNA polymerase is poised for activation across the genome

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4402150

RNA polymerase stalling at developmental control genes in the Drosophila melanogaster embryo

12 July 2018

1 reference

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A chromatin landmark and transcription initiation at most promoters in human cells

12 July 2018

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Properties of RNA polymerase II elongation complexes before and after the P-TEFb-mediated transition into productive elongation.

12 July 2018

1 reference

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Controlling the elongation phase of transcription with P-TEFb

12 July 2018

1 reference

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A bivalent chromatin structure marks key developmental genes in embryonic stem cells

12 July 2018

1 reference

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BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3

12 July 2018

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Human transcription elongation factor NELF: identification of novel subunits and reconstitution of the functionally active complex

12 July 2018

1 reference

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NELF, a multisubunit complex containing RD, cooperates with DSIF to repress RNA polymerase II elongation

12 July 2018

1 reference

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A constitutively active and nuclear form of the MAP kinase ERK2 is sufficient for neurite outgrowth and cell transformation

12 July 2018

1 reference

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FGF stimulation of the Erk1/2 signalling cascade triggers transition of pluripotent embryonic stem cells from self-renewal to lineage commitment.

12 July 2018

1 reference

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A discrete period of FGF-induced Erk1/2 signalling is required for vertebrate neural specification.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4402150

NELF interacts with CBC and participates in 3' end processing of replication-dependent histone mRNAs.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4402150

Early lineage segregation between epiblast and primitive endoderm in mouse blastocysts through the Grb2-MAPK pathway

26 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25773599

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.MOLCEL.2015.02.003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25773599%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25773599%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

PubMed publication ID

25773599

1 reference