Glutathione S-transferase A1 genetic variants reduce busulfan clearance in children undergoing hematopoietic cell transplantation (Q35486314)

8 August 2017

title

Glutathione S-transferase A1 genetic variants reduce busulfan clearance in children undergoing hematopoietic cell transplantation (English)

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8 August 2017

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3

K Scott Baker

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8 August 2017

L'Aurelle Johnson

1

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8 August 2017

Paul J Orchard

2

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8 August 2017

Richard Brundage

4

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8 August 2017

Qing Cao

5

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8 August 2017

Xinjing Wang

6

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8 August 2017

Erica Langer

7

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8 August 2017

Sharein Farag-El Maasah

8

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8 August 2017

Julie A Ross

9

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8 August 2017

Rory Remmel

10

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8 August 2017

Pamala A Jacobson

11

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8 August 2017

publication date

17 July 2008

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The Journal of Clinical Pharmacology

8 August 2017

published in

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8 August 2017

volume

48

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8 August 2017

issue

9

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8 August 2017

page(s)

1052-1062

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Predicting drug response and toxicity based on gene polymorphisms

8 August 2017

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Intravenous versus oral busulfan as part of a busulfan/cyclophosphamide preparative regimen for allogeneic hematopoietic stem cell transplantation: decreased incidence of hepatic venoocclusive disease (HVOD), HVOD-related mortality, and overall 100-

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Busulfan systemic exposure relative to regimen-related toxicity and acute graft-versus-host disease: defining a therapeutic window for i.v. BuCy2 in chronic myelogenous leukemia

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Pharmacokinetics of intravenous busulfan in children prior to stem cell transplantation

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Effect of polymorphism in the human glutathione S-transferase A1 promoter on hepatic GSTA1 and GSTA2 expression

27 July 2018

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Glutathione S-transferase activity influences busulfan pharmacokinetics in patients with beta thalassemia major undergoing bone marrow transplantation

27 July 2018

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An evaluation of engraftment, toxicity and busulfan concentration in children receiving bone marrow transplantation for leukemia or genetic disease

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Up-regulation of glutathione S-transferase activity in enterocytes of young children

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Busulfan conjugation by glutathione S-transferases alpha, mu, and pi.

27 July 2018

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Venoocclusive disease of the liver following bone marrow transplantation

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Busulfan concentration and graft rejection in pediatric patients undergoing hematopoietic stem cell transplantation

27 July 2018

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Plasma concentration monitoring of busulfan: does it improve clinical outcome?

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Busulfan levels are influenced by prior treatment and are associated with hepatic veno-occlusive disease and early mortality but not with delayed complications following marrow transplantation

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Specificities of human glutathione S-transferase isozymes toward anti-diol epoxides of methylchrysenes.

21 January 2018

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Glutathione S-transferase M1 polymorphism: a risk factor for hepatic venoocclusive disease in bone marrow transplantation

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Influence of glutathione S-transferase A1 polymorphism on the pharmacokinetics of busulfan

21 January 2018

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Intravenous busulfan for allogeneic hematopoietic stem cell transplantation in infants: clinical and pharmacokinetic results

21 January 2018

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I.V. busulfan in pediatrics: a novel dosing to improve safety/efficacy for hematopoietic progenitor cell transplantation recipients

21 January 2018

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Population pharmacokinetics of intravenous busulfan in patients undergoing hematopoietic stem cell transplantation

21 January 2018

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Intravenous busulfan in children prior to stem cell transplantation: study of pharmacokinetics in association with early clinical outcome and toxicity

21 January 2018

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Genetic polymorphisms of glutathione S-transferase A1, the major glutathione S-transferase in human liver: consequences for enzyme expression and busulfan conjugation

21 January 2018

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Metabolic gene polymorphism frequencies in control populations

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Busulfan disposition: the role of therapeutic monitoring in bone marrow transplantation induction regimens

26 September 2018

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12 December 2020

Busulfan pharmacokinetics using a single daily high-dose regimen in children with acute leukemia

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12 December 2020

Graft-rejection and toxicity following bone marrow transplantation in relation to busulfan pharmacokinetics

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12 December 2020

Busulfan disposition and hepatic veno-occlusive disease in children undergoing bone marrow transplantation

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12 December 2020

Busulfan-glutathione conjugation catalyzed by human liver cytosolic glutathione S-transferases

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12 December 2020

Age-dependent tetrahydrothiophenium ion formation in young children and adults receiving high-dose busulfan

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12 December 2020

Therapeutic monitoring of busulfan in hematopoietic stem cell transplantation

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12 December 2020

Routine analysis of plasma busulfan by gas chromatography-mass fragmentography

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12 December 2020

Pharmacokinetic disposition and clinical outcomes in infants and children receiving intravenous busulfan for allogeneic hematopoietic stem cell transplantation

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12 December 2020

Prospective validation of a novel IV busulfan fixed dosing for paediatric patients to improve therapeutic AUC targeting without drug monitoring

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12 December 2020

Identifiers

DOI

10.1177/0091270008321940

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8 August 2017

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8 August 2017

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