Serine side chain-linked peptidomimetic conjugates of cyclic HPMPC and HPMPA: synthesis and interaction with hPEPT1. (Q35499525)

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15 February 2020

title

Serine side chain-linked peptidomimetic conjugates of cyclic HPMPC and HPMPA: synthesis and interaction with hPEPT1 (English)

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15 February 2020

4

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15 February 2020

author name string

Larryn W Peterson

1

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15 February 2020

Monica Sala-Rabanal

2

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15 February 2020

Ivan S Krylov

3

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15 February 2020

Boris A Kashemirov

5

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15 February 2020

Charles E McKenna

6

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15 February 2020

language of work or name

English

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publication date

7 October 2010

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15 February 2020

published in

Molecular Pharmaceutics

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15 February 2020

volume

7

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15 February 2020

issue

6

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15 February 2020

page(s)

2349-2361

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Alkoxyalkyl prodrugs of acyclic nucleoside phosphonates enhance oral antiviral activity and reduce toxicity: current state of the art.

15 February 2020

cites work

1 reference

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Inhibition of intracellular dipeptide hydrolysis uncovers large outward transport currents of the peptide transporter PEPT1 in Xenopus oocytes

27 July 2018

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Synthesis, metabolism and cellular permeability of enzymatically stable dipeptide prodrugs of acyclovir

27 July 2018

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Serine peptide phosphoester prodrugs of cyclic cidofovir: synthesis, transport, and antiviral activity

27 July 2018

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New antiviral nucleoside prodrugs await application

27 July 2018

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Interactions of a nonpeptidic drug, valacyclovir, with the human intestinal peptide transporter (hPEPT1) expressed in a mammalian cell line

27 July 2018

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Direct evidence for peptide transporter (PepT1)-mediated uptake of a nonpeptide prodrug, valacyclovir

27 July 2018

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Mechanisms of the human intestinal H+-coupled oligopeptide transporter hPEPT1.

27 July 2018

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The in vitro transport of model thiodipeptide prodrugs designed to target the intestinal oligopeptide transporter, PepT1.

27 July 2018

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Modeling of the intestinal peptide transporter hPepT1 and analysis of its transport capacities by docking and pharmacophore mapping

26 September 2018

1 reference

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How drugs interact with transporters: SGLT1 as a model

26 September 2018

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Molecular mechanism of dipeptide and drug transport by the human renal H+/oligopeptide cotransporter hPEPT2.

26 September 2018

1 reference

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Modeling of drug-transporter interactions using structural information

26 September 2018

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QSAR models for the human H(+)/peptide symporter, hPEPT1: affinity prediction using alignment-independent descriptors

26 September 2018

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Molecular interactions between dipeptides, drugs and the human intestinal H+ -oligopeptide cotransporter hPEPT1.

26 September 2018

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Clinical Potential of the Acyclic Nucleoside Phosphonates Cidofovir, Adefovir, and Tenofovir in Treatment of DNA Virus and Retrovirus Infections

26 September 2018

1 reference

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Synthesis and characterization of novel dipeptide ester prodrugs of acyclovir

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205993

5'-Amino acid esters of antiviral nucleosides, acyclovir, and AZT are absorbed by the intestinal PEPT1 peptide transporter

26 September 2018

1 reference

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Conversion of 1-[((S)-2-hydroxy-2-oxo-1,4,2-dioxaphosphorinan-5-yl)methyl]cytosine to cidofovir by an intracellular cyclic CMP phosphodiesterase

26 September 2018

1 reference

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Human intestinal H+/peptide cotransporter. Cloning, functional expression, and chromosomal localization

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205993

Peptide transporters and their roles in physiological processes and drug disposition

26 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20929265

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Prodrug approaches to improving the oral absorption of antiviral nucleotide analogues

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20929265

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/MP100186B

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15 February 2020

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15 February 2020

PubMed publication ID

20929265

1 reference