Interleukin-12 is produced by macrophages in response to live or killed Bordetella pertussis and enhances the efficacy of an acellular pertussis vaccine by promoting induction of Th1 cells (Q35532427)

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scientific article published on December 1996

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English	Interleukin-12 is produced by macrophages in response to live or killed Bordetella pertussis and enhances the efficacy of an acellular pertussis vaccine by promoting induction of Th1 cells	scientific article published on December 1996

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scholarly article

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21 October 2019

Interleukin-12 is produced by macrophages in response to live or killed Bordetella pertussis and enhances the efficacy of an acellular pertussis vaccine by promoting induction of Th1 cells (English)

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21 October 2019

Bordetella pertussis

1 reference

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inferred from title

pertussis vaccine

1 reference

based on heuristic

inferred from title

Kingston H Mills

4

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21 October 2019

author name string

B P Mahon

1

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21 October 2019

M S Ryan

2

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21 October 2019

F Griffin

3

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21 October 2019

language of work or name

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publication date

1 December 1996

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21 October 2019

Infection and Immunity

1 reference

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21 October 2019

64

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21 October 2019

12

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21 October 2019

5295-5301

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8945580%20AND%20SRC:MED&resulttype=core&format=json

21 October 2019

Immunization with a soluble recombinant HIV protein entrapped in biodegradable microparticles induces HIV-specific CD8+ cytotoxic T lymphocytes and CD4+ Th1 cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=174522

27 July 2018

IL-12 protects immunocompetent and immunodeficient neonatal mice against infection with Cryptosporidium parvum.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=174522

27 July 2018

A controlled trial of a two-component acellular, a five-component acellular, and a whole-cell pertussis vaccine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=174522

27 July 2018

Effective immunization against Bordetella pertussis respiratory infection in mice is dependent on induction of cell-mediated immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=174522

27 July 2018

Interleukin 12 is required for the T-lymphocyte-independent induction of interferon gamma by an intracellular parasite and induces resistance in T-cell-deficient hosts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=174522

27 July 2018

Resolution of cutaneous leishmaniasis: interleukin 12 initiates a protective T helper type 1 immune response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=174522

27 July 2018

Recombinant interleukin 12 cures mice infected with Leishmania major

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=174522

27 July 2018

Development of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=174522

27 July 2018

Role of cytokines in determining T-lymphocyte function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=174522

27 July 2018

Production of gamma interferon by natural killer cells from Toxoplasma gondii-infected SCID mice: regulation by interleukin-10, interleukin-12, and tumor necrosis factor alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=174522

27 July 2018

Endogenous interleukin 12 (IL-12) regulates granuloma formation induced by eggs of Schistosoma mansoni and exogenous IL-12 both inhibits and prophylactically immunizes against egg pathology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=174522

27 July 2018

The adjuvant effect of interleukin-12 in a vaccine against Leishmania major.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=174522

27 July 2018

Interleukin 12 acts directly on CD4+ T cells to enhance priming for interferon gamma production and diminishes interleukin 4 inhibition of such priming

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=174522

27 July 2018

Endogenous interleukin-12 is involved in resistance to Brucella abortus infection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=174522

27 July 2018

Poliovirus-specific CD4+ Th1 clones with both cytotoxic and helper activity mediate protective humoral immunity against a lethal poliovirus infection in transgenic mice expressing the human poliovirus receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=174522

27 July 2018

Aerosol infection of mice with Bordetella pertussis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=174522

27 July 2018

Pertussis vaccine: present status and future prospects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=174522

27 July 2018

Invasion of HeLa 229 cells by virulent Bordetella pertussis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=174522

27 July 2018

Heterogeneity of cytokine secretion patterns and functions of helper T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=174522

27 July 2018

Integrin-mediated localization of Bordetella pertussis within macrophages: role in pulmonary colonization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=174522

27 July 2018

Lymphokine secretion and cytotoxic activity of human CD4+ T-cell clones against Bordetella pertussis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=174522

27 July 2018

Uptake and intracellular survival of Bordetella pertussis in human macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=174522

27 July 2018

Proliferative responses and gamma interferon and tumor necrosis factor production by lymphocytes isolated from tracheobroncheal lymph nodes and spleen of mice aerosol infected with Bordetella pertussis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=174522

27 July 2018

IL-12, as an adjuvant, promotes a T helper 1 cell, but does not suppress a T helper 2 cell recall response.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=174522

26 September 2018

Regulation of murine macrophage IL-12 production. Activation of macrophages in vivo, restimulation in vitro, and modulation by other cytokines.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=174522

26 September 2018

Cell-mediated immunity to Bordetella pertussis: role of Th1 cells in bacterial clearance in a murine respiratory infection model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=174522

26 September 2018

IL-12 increases resistance of BALB/c mice to Mycobacterium tuberculosis infection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=174522

26 September 2018

Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=174522

26 September 2018

IL-12 stimulates an antiviral type 1 cytokine response but lacks adjuvant activity in IFN-gamma-receptor-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=174522

26 September 2018

A Controlled Trial of Two Acellular Vaccines and One Whole-Cell Vaccine against Pertussis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=174522

15 November 2018

Cellular immunity in pertussis

1 reference

https://pubmed.ncbi.nlm.nih.gov/8945580

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of IL-12 on in vivo cytokine gene expression and Ig isotype selection

1 reference

https://pubmed.ncbi.nlm.nih.gov/8945580

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neutralization of IL-12 decreases resistance to Listeria in SCID and C.B-17 mice. Reversal by IFN-gamma

1 reference

https://pubmed.ncbi.nlm.nih.gov/8945580

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of IL-12 on helper T cell-dependent immune responses in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/8945580

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Th1/Th2 cell dichotomy in acquired immunity to Bordetella pertussis: variables in the in vivo priming and in vitro cytokine detection techniques affect the classification of T-cell subsets as Th1, Th2 or Th0

1 reference

https://pubmed.ncbi.nlm.nih.gov/8945580

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nonviable bacterial antigens administered with IL-12 generate antigen-specific T cell responses and protective immunity against Listeria monocytogenes

1 reference

https://pubmed.ncbi.nlm.nih.gov/8945580

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An absolute and restricted requirement for IL-12 in natural killer cell IFN-gamma production and antiviral defense. Studies of natural killer and T cell responses in contrasting viral infections

1 reference

https://pubmed.ncbi.nlm.nih.gov/8945580

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protective effectiveness of an endotoxin-depleted pertussis vaccine

1 reference

https://pubmed.ncbi.nlm.nih.gov/8945580

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of hyperreactivity to endotoxin on the toxicity of pertussis vaccine and pertussis toxin in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/8945580

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Murine Th1 and Th2 clones proliferate optimally in response to distinct antigen-presenting cell populations

1 reference

https://pubmed.ncbi.nlm.nih.gov/8945580

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/IAI.64.12.5295-5301.1996

0 references

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8945580%20AND%20SRC:MED&resulttype=core&format=json

21 October 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8945580%20AND%20SRC:MED&resulttype=core&format=json

21 October 2019

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