Specific knockdown of uPA/uPAR attenuates invasion in glioblastoma cells and xenografts by inhibition of cleavage and trafficking of Notch -1 receptor (Q35533533)

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scientific article published on 17 October 2011

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English	Specific knockdown of uPA/uPAR attenuates invasion in glioblastoma cells and xenografts by inhibition of cleavage and trafficking of Notch -1 receptor	scientific article published on 17 October 2011

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scholarly article

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14 January 2020

Specific knockdown of uPA/uPAR attenuates invasion in glioblastoma cells and xenografts by inhibition of cleavage and trafficking of Notch -1 receptor (English)

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14 January 2020

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author name string

Hari Raghu

1

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14 January 2020

Dzung H Dinh

3

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14 January 2020

Meena Gujrati

4

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14 January 2020

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17 October 2011

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14 January 2020

Molecular Cancer

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14 January 2020

10

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14 January 2020

130

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14 January 2020

Notch Signaling in the Regulation of Stem Cell Self-Renewal and Differentiation

1 reference

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27 July 2018

Suppression of uPA and uPAR Attenuates Angiogenin Mediated Angiogenesis in Endothelial and Glioblastoma Cell Lines

1 reference

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Targeting MMP-9, uPAR, and cathepsin B inhibits invasion, migration and activates apoptosis in prostate cancer cells

1 reference

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27 July 2018

The functional role of Notch signaling in human gliomas

1 reference

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The oncogenic roles of Notch1 in astrocytic gliomas in vitro and in vivo

1 reference

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27 July 2018

Inhibition of NOTCH signaling by gamma secretase inhibitor engages the RB pathway and elicits cell cycle exit in T-cell acute lymphoblastic leukemia cells.

1 reference

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27 July 2018

Exploitation of the Notch signaling pathway as a novel target for cancer therapy.

1 reference

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27 July 2018

Targeted knockdown of Notch1 inhibits invasion of human prostate cancer cells concomitant with inhibition of matrix metalloproteinase-9 and urokinase plasminogen activator

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210098

27 July 2018

Notch-1 regulates Akt signaling pathway and the expression of cell cycle regulatory proteins cyclin D1, CDK2 and p21 in T-ALL cell lines

1 reference

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27 July 2018

Notch1 is an effector of Akt and hypoxia in melanoma development

1 reference

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Mind bomb 1 in the lymphopoietic niches is essential for T and marginal zone B cell development

1 reference

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27 July 2018

Modulating Notch signaling by pathway-intrinsic and pathway-extrinsic mechanisms.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210098

27 July 2018

Signaling pathways in medulloblastoma

1 reference

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27 July 2018

Notch and cancer: a double-edged sword

1 reference

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27 July 2018

Intraperitoneal injection of a hairpin RNA-expressing plasmid targeting urokinase-type plasminogen activator (uPA) receptor and uPA retards angiogenesis and inhibits intracranial tumor growth in nude mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210098

27 July 2018

Down-regulation of uPAR and uPA activates caspase-mediated apoptosis and inhibits the PI3K/AKT pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210098

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Reactivity patterns of cytochrome P450 enzymes: multifunctionality of the active species, and the two states-two oxidants conundrum

1 reference

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27 July 2018

Contribution of Notch signaling activation to human glioblastoma multiforme.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210098

27 July 2018

Blockade of Dll4 inhibits tumour growth by promoting non-productive angiogenesis

1 reference

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27 July 2018

Notch signaling in the regulation of tumor angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210098

27 July 2018

Notch signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210098

27 July 2018

Angiogenesis in gliomas: biology and molecular pathophysiology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210098

27 July 2018

Recent insights into the role of Notch signaling in tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210098

27 July 2018

Expression of Notch-1 and its ligands, Delta-like-1 and Jagged-1, is critical for glioma cell survival and proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210098

27 July 2018

Stable transfection of urokinase-type plasminogen activator antisense construct modulates invasion of human glioblastoma cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210098

27 July 2018

Calcium depletion dissociates and activates heterodimeric notch receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210098

27 July 2018

Notch signaling: cell fate control and signal integration in development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210098

27 July 2018

Roles for proteolysis and trafficking in notch maturation and signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210098

27 July 2018

Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210098

27 July 2018

Epithelial expression and chromosomal location of human TLE genes: implications for notch signaling and neoplasia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210098

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Reduction of caveolin and caveolae in oncogenically transformed cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210098

27 July 2018

TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210098

27 July 2018

Down-regulation of Notch-1 and Jagged-1 inhibits prostate cancer cell growth, migration and invasion, and induces apoptosis via inactivation of Akt, mTOR, and NF-kappaB signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210098

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MicroRNA-34a inhibits glioblastoma growth by targeting multiple oncogenes

1 reference

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26 September 2018

NOTCH and PI3K-AKT pathways intertwined.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210098

26 September 2018

Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210098

26 September 2018

Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210098

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Aberrant activation of notch signaling in human breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210098

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Notch3 signaling initiates choroid plexus tumor formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210098

26 September 2018

Down-regulation of Platelet-Derived Growth Factor-D Inhibits Cell Growth and Angiogenesis through Inactivation of Notch-1 and Nuclear Factor-κB Signaling

1 reference

https://api.crossref.org/works/10.1186%2F1476-4598-10-130

21 January 2018

Crosstalk between tumor and endothelial cells promotes tumor angiogenesis by MAPK activation of Notch signaling

1 reference

https://api.crossref.org/works/10.1186%2F1476-4598-10-130

21 January 2018

Off the beaten pathway: the complex cross talk between Notch and NF-kappaB

1 reference

https://pubmed.ncbi.nlm.nih.gov/22004682

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Down-regulation of notch-1 inhibits invasion by inactivation of nuclear factor-kappaB, vascular endothelial growth factor, and matrix metalloproteinase-9 in pancreatic cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22004682

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1186/1476-4598-10-130

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22004682%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

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14 January 2020

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14 January 2020

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