Fibroblast growth factor 23 regulates renal 1,25-dihydroxyvitamin D and phosphate metabolism via the MAP kinase signaling pathway in Hyp mice (Q35538411)

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scientific article published on August 2011

Language	Label	Description	Also known as
English	Fibroblast growth factor 23 regulates renal 1,25-dihydroxyvitamin D and phosphate metabolism via the MAP kinase signaling pathway in Hyp mice	scientific article published on August 2011

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scholarly article

1 reference

Europe PubMed Central

8 August 2017

Fibroblast growth factor 23 regulates renal 1,25-dihydroxyvitamin D and phosphate metabolism via the MAP kinase signaling pathway in Hyp mice (English)

1 reference

Europe PubMed Central

8 August 2017

author name string

Daniel Ranch

1

1 reference

Europe PubMed Central

8 August 2017

Martin Yh Zhang

2

1 reference

Europe PubMed Central

8 August 2017

Anthony A Portale

3

1 reference

Europe PubMed Central

8 August 2017

Farzana Perwad

4

1 reference

Europe PubMed Central

8 August 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

1 August 2011

1 reference

Europe PubMed Central

8 August 2017

Journal of Bone and Mineral Research

1 reference

Europe PubMed Central

8 August 2017

26

1 reference

Europe PubMed Central

8 August 2017

8

1 reference

Europe PubMed Central

8 August 2017

1883-1890

1 reference

Europe PubMed Central

8 August 2017

Initial FGF23-mediated signaling occurs in the distal convoluted tubule

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409871

12 July 2018

The discovery of the benzhydroxamate MEK inhibitors CI-1040 and PD 0325901.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409871

12 July 2018

FGF-23-Klotho signaling stimulates proliferation and prevents vitamin D-induced apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409871

12 July 2018

Advances in the development of cancer therapeutics directed against the RAS-mitogen-activated protein kinase pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409871

12 July 2018

The parathyroid is a target organ for FGF23 in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409871

12 July 2018

The selectivity of protein kinase inhibitors: a further update

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409871

12 July 2018

Fibroblast growth factor 23 impairs phosphorus and vitamin D metabolism in vivo and suppresses 25-hydroxyvitamin D-1alpha-hydroxylase expression in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409871

12 July 2018

FGF23 concentrations vary with disease status in autosomal dominant hypophosphatemic rickets.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409871

12 July 2018

Klotho converts canonical FGF receptor into a specific receptor for FGF23

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409871

12 July 2018

Loss of DMP1 causes rickets and osteomalacia and identifies a role for osteocytes in mineral metabolism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409871

12 July 2018

Regulation of fibroblast growth factor-23 signaling by klotho

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409871

12 July 2018

Homozygous ablation of fibroblast growth factor-23 results in hyperphosphatemia and impaired skeletogenesis, and reverses hypophosphatemia in Phex-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409871

12 July 2018

FGF-23 is a potent regulator of vitamin D metabolism and phosphate homeostasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409871

12 July 2018

Segment-specific expression of sodium-phosphate cotransporters NaPi-IIa and -IIc and interacting proteins in mouse renal proximal tubules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409871

12 July 2018

Regulation of fibroblastic growth factor 23 expression but not degradation by PHEX.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409871

12 July 2018

The autosomal dominant hypophosphatemic rickets R176Q mutation in fibroblast growth factor 23 resists proteolytic cleavage and enhances in vivo biological potency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409871

12 July 2018

Protein kinases--the major drug targets of the twenty-first century?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409871

12 July 2018

Fibroblast growth factor (FGF)-23 inhibits renal phosphate reabsorption by activation of the mitogen-activated protein kinase pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409871

12 July 2018

Autosomal-dominant hypophosphatemic rickets (ADHR) mutations stabilize FGF-23

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409871

12 July 2018

Lipopolysaccharide activation of the MEK-ERK1/2 pathway in human monocytic cells mediates tissue factor and tumor necrosis factor alpha expression by inducing Elk-1 phosphorylation and Egr-1 expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409871

12 July 2018

Stress-induced immediate-early gene, egr-1, involves activation of p38/JNK1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409871

12 July 2018

Mutational analysis of the PEX gene in patients with X-linked hypophosphatemic rickets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409871

12 July 2018

Distribution of mutations in the PEX gene in families with X-linked hypophosphataemic rickets (HYP).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409871

12 July 2018

Pex/PEX tissue distribution and evidence for a deletion in the 3' region of the Pex gene in X-linked hypophosphatemic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409871

12 July 2018

A gene (PEX) with homologies to endopeptidases is mutated in patients with X-linked hypophosphatemic rickets. The HYP Consortium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409871

12 July 2018

Abnormal regulation of renal vitamin D catabolism by dietary phosphate in murine X-linked hypophosphatemic rickets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409871

12 July 2018

Hypophosphatemia: mouse model for human familial hypophosphatemic (vitamin D-resistant) rickets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409871

12 July 2018

Increased circulatory level of biologically active full-length FGF-23 in patients with hypophosphatemic rickets/osteomalacia

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.401

21 January 2018

Fibroblast growth factor 23 in oncogenic osteomalacia and X-linked hypophosphatemia

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.401

21 January 2018

Pathogenic role of Fgf23 in Hyp mice.

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.401

21 January 2018

Transgenic mice expressing fibroblast growth factor 23 under the control of the alpha1(I) collagen promoter exhibit growth retardation, osteomalacia, and disturbed phosphate homeostasis

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.401

21 January 2018

Mutant FGF-23 responsible for autosomal dominant hypophosphatemic rickets is resistant to proteolytic cleavage and causes hypophosphatemia in vivo.

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.401

21 January 2018

Genetic dissection of phosphate- and vitamin D-mediated regulation of circulating Fgf23 concentrations

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.401

21 January 2018

Dietary and serum phosphorus regulate fibroblast growth factor 23 expression and 1,25-dihydroxyvitamin D metabolism in mice

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.401

21 January 2018

Disordered regulation of renal 25-hydroxyvitamin D-1alpha-hydroxylase gene expression by phosphorus in X-linked hypophosphatemic (hyp) mice

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.401

21 January 2018

FGF-23 transgenic mice demonstrate hypophosphatemic rickets with reduced expression of sodium phosphate cotransporter type IIa.

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.401

21 January 2018

Differential effects of Npt2a gene ablation and X-linked Hyp mutation on renal expression of Npt2c.

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.401

21 January 2018

Secondary hyperparathyroidism in X-linked hypophosphatemic mice.

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.401

21 January 2018

Anti-FGF23 neutralizing antibodies show the physiological role and structural features of FGF23.

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.401

21 January 2018

Therapeutic effects of anti-FGF23 antibodies in hypophosphatemic rickets/osteomalacia.

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.401

21 January 2018

Growth hormone normalizes renal 1,25-dihydroxyvitamin D3-24-hydroxylase gene expression but not Na+-phosphate cotransporter (Npt2) mRNA in phosphate-deprived Hyp mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/21472778

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dietary phosphorus transcriptionally regulates 25-hydroxyvitamin D-1alpha-hydroxylase gene expression in the proximal renal tubule

1 reference

https://pubmed.ncbi.nlm.nih.gov/21472778

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacodynamic and toxicokinetic evaluation of the novel MEK inhibitor, PD0325901, in the rat following oral and intravenous administration

1 reference

https://pubmed.ncbi.nlm.nih.gov/21472778

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutational analysis of PHEX gene in X-linked hypophosphatemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/21472778

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation of renal proximal tubular brush-border membranes

1 reference

https://pubmed.ncbi.nlm.nih.gov/21472778

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/JBMR.401

1 reference

Europe PubMed Central

8 August 2017

1 reference

Europe PubMed Central

8 August 2017

1 reference

Europe PubMed Central

8 August 2017

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