RO1138452 and RO3244794: characterization of structurally distinct, potent and selective IP (prostacyclin) receptor antagonists (Q35545236)

8 August 2017

title

RO1138452 and RO3244794: characterization of structurally distinct, potent and selective IP (prostacyclin) receptor antagonists (English)

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8 August 2017

1

Keith R Bley

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8 August 2017

Anindya Bhattacharya

2

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8 August 2017

Don V Daniels

3

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8 August 2017

Joel Gever

4

1 reference

8 August 2017

Alam Jahangir

5

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8 August 2017

Counde O'Yang

6

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8 August 2017

Steven Smith

7

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8 August 2017

Dinesh Srinivasan

8

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8 August 2017

Anthony P D W Ford

9

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8 August 2017

Mary-Frances Jett

10

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8 August 2017

language of work or name

English

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publication date

1 February 2006

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British Journal of Pharmacology

8 August 2017

published in

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8 August 2017

volume

147

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8 August 2017

issue

3

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8 August 2017

page(s)

335-345

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A prostacyclin receptor antagonist inhibits the sensitized release of substance P from rat sensory neurons

8 August 2017

cites work

1 reference

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Sensitization of TRPV1 by EP1 and IP reveals peripheral nociceptive mechanism of prostaglandins

12 July 2018

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Dimerization of the human receptors for prostacyclin and thromboxane facilitates thromboxane receptor-mediated cAMP generation

12 July 2018

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Role of extracellular cysteine residues in dimerization/oligomerization of the human prostacyclin receptor.

12 July 2018

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Human prostacyclin receptor

12 July 2018

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12 July 2018

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A novel pathway of prostacyclin signaling-hanging out with nuclear receptors

12 July 2018

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Role of prostacyclin in the cardiovascular response to thromboxane A2

12 July 2018

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A novel subtype of prostacyclin receptor in the central nervous system.

12 July 2018

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Characterization of the analgesic and anti-inflammatory activities of ketorolac and its enantiomers in the rat.

12 July 2018

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Characterization of prostanoid receptor-evoked responses in rat sensory neurones

12 July 2018

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Altered pain perception and inflammatory response in mice lacking prostacyclin receptor

12 July 2018

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Molecular biology of prostanoid receptors; an overview

12 July 2018

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A novel subtype of the prostacyclin receptor expressed in the central nervous system.

12 July 2018

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International Union of Pharmacology classification of prostanoid receptors: properties, distribution, and structure of the receptors and their subtypes

12 July 2018

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New insights into the mode of action of anti-inflammatory drugs.

12 July 2018

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Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

12 July 2018

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Production of prostacyclin in mice following intraperitoneal injection of acetic acid, phenylbenzoquinone and zymosan: its role in the writhing response

12 July 2018

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Quantitative comparison of the analgesic and anti-inflammatory activities of aspirin, phenacetin and acetaminophen in rodents

12 July 2018

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Prostaglandins and thromboxanes

12 July 2018

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Functional role of prostacyclin receptor in rat dorsal root ganglion neurons

12 July 2018

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COX-2-derived prostacyclin confers atheroprotection on female mice

26 September 2018

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Discovery and SAR development of 2-(phenylamino) imidazolines as prostacyclin receptor antagonists [corrected].

26 September 2018

1 reference

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Weight bearing as a measure of disease progression and efficacy of anti-inflammatory compounds in a model of monosodium iodoacetate-induced osteoarthritis

26 September 2018

1 reference

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COX-2–Dependent Cardiac Failure in Gh/tTG Transgenic Mice

26 September 2018

1 reference

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The prostaglandin E2 receptor-1 (EP-1) mediates acid-induced visceral pain hypersensitivity in humans

26 September 2018

1 reference

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Central nociceptive role of prostacyclin (IP) receptor induced by peripheral inflammation

26 September 2018

1 reference

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Impaired receptor binding and activation associated with a human prostacyclin receptor polymorphism

26 September 2018

1 reference

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Roles of prostaglandin I(2) and thromboxane A(2) in cardiac ischemia-reperfusion injury: a study using mice lacking their respective receptors

26 September 2018

1 reference

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The role of IP prostanoid receptors in inflammatory pain

26 September 2018

1 reference

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Prostanoid receptor heterogeneity through alternative mRNA splicing

26 September 2018

1 reference

12 December 2020

Intrinsic prostacyclin contributes to exudation induced by bradykinin or carrageenin: A study on the paw edema induced in IP-Receptor-deficient mice

1 reference

12 December 2020

Possibilities for clinical use of prostacyclin in vascular disease

1 reference

12 December 2020

The effects of peripheral administration of a novel selective antagonist for prostaglandin E receptor subtype EP(1), ONO-8711, in a rat model of postoperative pain

1 reference

12 December 2020

Major roles of prostanoid receptors IP and EP3 in endotoxin-induced enhancement of pain perception11Abbreviations:, prostaglandin E receptor subtype 1; IP, prostaglandin I receptor; LPS, lipopolysaccharide; and WT, wild-type mice

1 reference

12 December 2020

Arterial walls generate from prostaglandin endoperoxides a substance (prostaglandin X) which relaxes strips of mesenteric and coeliac ateries and inhibits platelet aggregation

1 reference

12 December 2020

Rabbit cortical collecting ducts express a novel prostacyclin receptor.

1 reference

12 December 2020

Identifiers

DOI

10.1038/SJ.BJP.0706554

1 reference

release_ir7mbromfbfo5cyszbaqliowka

8 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ir7mbromfbfo5cyszbaqliowka

24 November 2022

mapped directly with Wikidata item

PMC publication ID

1751302

1 reference

8 August 2017

1 reference