MALDI Imaging mass spectrometry: current frontiers and perspectives in pathology research and practice (Q35549222)

8 August 2017

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title

MALDI Imaging mass spectrometry: current frontiers and perspectives in pathology research and practice (English)

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matrix-assisted laser desorption/ionization

8 August 2017

main subject

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author name string

Michaela Aichler

series ordinal

1

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8 August 2017

Axel Walch

series ordinal

2

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8 August 2017

language of work or name

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26 January 2015

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8 August 2017

published in

Laboratory Investigation

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8 August 2017

volume

95

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8 August 2017

issue

4

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8 August 2017

page(s)

422-431

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https://scigraph.springernature.com/pub.10.1038/labinvest.2014.156

8 August 2017

exact match

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cites work

Imaging mass spectrometry: a new tool for pathology in a molecular age

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Analysis of tissue specimens by matrix-assisted laser desorption/ionization imaging mass spectrometry in biological and clinical research.

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Molecular imaging of biological samples: localization of peptides and proteins using MALDI-TOF MS.

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Imaging mass spectrometry: a new technology for the analysis of protein expression in mammalian tissues

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Ion Formation in MALDI: The Cluster Ionization Mechanism

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Compelling evidence for Lucky Survivor and gas phase protonation: the unified MALDI analyte protonation mechanism

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Mass spectrometry imaging with high resolution in mass and space

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Histology by mass spectrometry: label-free tissue characterization obtained from high-accuracy bioanalytical imaging

21 January 2018

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Mass spectrometry imaging with high resolution in mass and space (HR(2) MSI) for reliable investigation of drug compound distributions on the cellular level

21 January 2018

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Imaging mass spectrometry of intact proteins from alcohol-preserved tissue specimens: bypassing formalin fixation.

21 January 2018

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https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

MALDI imaging mass spectrometry: molecular snapshots of biochemical systems

21 January 2018

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https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Improving tissue preparation for matrix-assisted laser desorption ionization mass spectrometry imaging. Part 1: using microspotting

21 January 2018

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Detection of high molecular weight proteins by MALDI imaging mass spectrometry.

21 January 2018

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https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Laser capture microdissection

21 January 2018

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https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Laser capture microdissection technology

21 January 2018

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https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

High-resolution metabolite imaging of light and dark treated retina using MALDI-FTICR mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Comprehensive identification of proteins from MALDI imaging

21 January 2018

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https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

MSiMass list: a public database of identifications for protein MALDI MS imaging.

21 January 2018

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https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Imaging mass spectrometry reveals modified forms of histone H4 as new biomarkers of microvascular invasion in hepatocellular carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Novel molecular tumour classification using MALDI-mass spectrometry imaging of tissue micro-array

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

High-throughput proteomic analysis of formalin-fixed paraffin-embedded tissue microarrays using MALDI imaging mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Imaging mass spectrometry of gastric carcinoma in formalin-fixed paraffin-embedded tissue microarray.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

MALDI mass spectrometric imaging based identification of clinically relevant signals in prostate cancer using large-scale tissue microarrays.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

MALDI imaging-based identification of prognostically relevant signals in bladder cancer using large-scale tissue microarrays

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Clinical response to chemotherapy in oesophageal adenocarcinoma patients is linked to defects in mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Cellular lipid metabolism and the role of lipids in progressive renal disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Minireview: lipid metabolism, metabolic diseases, and peroxisome proliferator-activated receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Longitudinal changes of adiponectin, carbohydrate and lipid metabolism in pregnant women at high risk for gestational diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Lipid metabolism in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Mass-spectrometry based oxidative lipidomics and lipid imaging: applications in traumatic brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

In situ structural characterization of phosphatidylcholines in brain tissue using MALDI-MS/MS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

MALDI reveals membrane lipid profile reversion in MDX mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Sublimation of new matrix candidates for high spatial resolution imaging mass spectrometry of lipids: enhanced information in both positive and negative polarities after 1,5-diaminonapthalene deposition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

In situ MALDI-TOF MS regional analysis of neutral phospholipids in lens tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Isolation and lipid characterization of cholesterol-enriched fractions in cortical and nuclear human lens fibers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Glycero- versus sphingo-phospholipids: correlations with human and non-human mammalian lens growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Mass spectrometry imaging of rat brain sections: nanomolar sensitivity with MALDI versus nanometer resolution by TOF-SIMS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Profiling and imaging of lipids on brain and liver tissue by matrix-assisted laser desorption/ ionization mass spectrometry using 2-mercaptobenzothiazole as a matrix

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Spatial and temporal alterations of phospholipids determined by mass spectrometry during mouse embryo implantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Localization and imaging of sialylated glycosphingolipids in brain tissue sections by MALDI mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Lipid geographical analysis of the primate macula by imaging mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Organ-specific distributions of lysophosphatidylcholine and triacylglycerol in mouse embryo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Imaging of lipids in spinal cord using intermediate pressure matrix-assisted laser desorption-linear ion trap/Orbitrap MS

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Liquid ionic matrixes for MALDI mass spectrometry imaging of lipids

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Imaging of phosphatidylcholines in the adult rat brain using MALDI-TOF MS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Imaging of lipid species by MALDI mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

High-spatial resolution matrix-assisted laser desorption ionization imaging analysis of glucosylceramide in spleen sections from a mouse model of Gaucher disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Mapping of phospholipids by MALDI imaging (MALDI-MSI): realities and expectations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Visualization of the cell-selective distribution of PUFA-containing phosphatidylcholines in mouse brain by imaging mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Visualizing spatial lipid distribution in porcine lens by MALDI imaging high-resolution mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Comprehensive imaging of porcine adrenal gland lipids by MALDI-FTMS using quercetin as a matrix.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Accumulated phosphatidylcholine (16:0/16:1) in human colorectal cancer; possible involvement of LPCAT4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Ultrahighly sensitive in situ metabolomic imaging for visualizing spatiotemporal metabolic behaviors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Paradoxical ATP elevation in ischemic penumbra revealed by quantitative imaging mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Energy management by enhanced glycolysis in G1-phase in human colon cancer cells in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Fine mapping the spatial distribution and concentration of unlabeled drugs within tissue micro-compartments using imaging mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Determination of paclitaxel distribution in solid tumors by nano-particle assisted laser desorption ionization mass spectrometry imaging

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Quantitative MALDI tandem mass spectrometric imaging of cocaine from brain tissue with a deuterated internal standard

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Mass spectrometry imaging for drug distribution studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

MALDI-MS-based imaging of small molecules and proteins in tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Direct analysis of drug candidates in tissue by matrix‐assisted laser desorption/ionization mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Examination of the distribution of the bioreductive drug AQ4N and its active metabolite AQ4 in solid tumours by imaging matrix-assisted laser desorption/ionisation mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Utility of imaging mass spectrometry (IMS) by matrix-assisted laser desorption ionization (MALDI) on an ion trap mass spectrometer in the analysis of drugs and metabolites in biological tissues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Analysis of erlotinib and its metabolites in rat tissue sections by MALDI quadrupole time-of-flight mass spectrometry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Direct molecular analysis of whole-body animal tissue sections by imaging MALDI mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Direct Molecular Analysis of Whole-Body Animal Tissue Sections by MALDI Imaging Mass Spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

MALDI mass spectrometric imaging of biological tissue sections

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Imaging mass spectrometry for visualization of drug and endogenous metabolite distribution: toward in situ pharmacometabolomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Applications of MALDI-MSI to Pharmaceutical Research

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Drug localization in different lung cancer phenotypes by MALDI mass spectrometry imaging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Qualitative and quantitative mass spectrometry imaging of drugs and metabolites in tissue at therapeutic levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Mass spectrometry imaging for drugs and metabolites

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

MALDI imaging mass spectrometry: bridging biology and chemistry in drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Qualitative and quantitative mass spectrometry imaging of drugs and metabolites

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Novel approach of MALDI drug imaging, immunohistochemistry, and digital image analysis for drug distribution studies in tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

MALDI imaging identifies prognostic seven-protein signature of novel tissue markers in intestinal-type gastric cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Identification of markers of taxane sensitivity using proteomic and genomic analyses of breast tumors from patients receiving neoadjuvant paclitaxel and radiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Application of MALDI imaging for the diagnosis of classical Hodgkin lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Cancer of unknown primary (CUP).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Cancer of unknown primary site

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Summary of the Standards, Options and Recommendations for the management of patients with carcinoma of unknown primary site (2002).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Tumor classification of six common cancer types based on proteomic profiling by MALDI imaging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Classification of HER2/neu status in gastric cancer using a breast-cancer derived proteome classifier

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Classification of HER2 receptor status in breast cancer tissues by MALDI imaging mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Imaging mass spectrometry--a new and promising method to differentiate Spitz nevi from Spitzoid malignant melanomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Proteomic profiling of mucosal and submucosal colonic tissues yields protein signatures that differentiate the inflammatory colitides

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Single-cell dissection of transcriptional heterogeneity in human colon tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Genetic clonal diversity predicts progression to esophageal adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Intratumoral heterogeneity of HER-2 gene amplification and protein overexpression in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Clonal evolution in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Imaging mass spectrometry of myxoid sarcomas identifies proteins and lipids specific to tumour type and grade, and reveals biochemical intratumour heterogeneity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Multiple statistical analysis techniques corroborate intratumor heterogeneity in imaging mass spectrometry datasets of myxofibrosarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

De novo discovery of phenotypic intratumour heterogeneity using imaging mass spectrometry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Matrix-assisted laser-desorption/ionization biotyper: experience in the routine of a University hospital.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Performance and cost analysis of matrix-assisted laser desorption ionization-time of flight mass spectrometry for routine identification of yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

Investigative pathology: leading the post-genomic revolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2014.156

MALDI imaging and profiling MS of higher mass proteins from tissue

21 January 2018

1 reference

12 December 2020

MALDI imaging on large-scale tissue microarrays identifies molecular features associated with tumour phenotype in oesophageal cancer.

1 reference

12 December 2020

Molecular imaging by mass spectrometry--looking beyond classical histology

1 reference

12 December 2020

Genetic heterogeneity and cancer drug resistance

1 reference

12 December 2020

Distribution and quantification of irinotecan and its active metabolite SN-38 in colon cancer murine model systems using MALDI MSI.

1 reference

12 December 2020

Imaging mass spectrometry to discriminate breast from pancreatic cancer metastasis in formalin-fixed paraffin-embedded tissues

1 reference

12 December 2020

Tissue molecular ion imaging by gold cluster ion bombardment

1 reference

12 December 2020

MALDI imaging on tissue microarrays identifies molecular features associated with renal cell cancer phenotype

1 reference

12 December 2020

10.1038/LABINVEST.2014.156

Identifiers

DOI

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8 August 2017

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