Thymidylate synthetase - a target enzyme in cancer chemotherapy (Q35549719)

8 August 2017

1 reference

title

Thymidylate synthetase - a target enzyme in cancer chemotherapy (English)

1 reference

8 August 2017

1 reference

1 reference

https://api.crossref.org/works/10.1016/0304-419X(77)90001-4

14 December 2022

1 reference

https://api.crossref.org/works/10.1016/0304-419X(77)90001-4

14 December 2022

author name string

P. V. Danenberg

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A145246

14 December 2022

language of work or name

English

0 references

publication date

1 December 1977

1 reference

8 August 2017

23 December 1977

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=145246

full work available at URL

14 December 2022

https://api.elsevier.com/content/article/PII:0304419X77900014?httpAccept=text/xml

1 reference

https://api.crossref.org/works/10.1016/0304-419X(77)90001-4

https://api.elsevier.com/content/article/PII:0304419X77900014?httpAccept=text/plain

14 December 2022

1 reference

https://api.crossref.org/works/10.1016/0304-419X(77)90001-4

Biochimica et Biophysica Acta

14 December 2022

published in

1 reference

8 August 2017

473

1 reference

8 August 2017

73-92

1 reference

8 August 2017

2

1 reference

Studies on the conversion of deoxyuridylic acid to thymidylic acid by a soluble extract from rat thymus

8 August 2017

1

1 reference

https://api.crossref.org/works/10.1016/0304-419X(77)90001-4

Mechanism of the Action of Thymidylate Synthetase

14 December 2022

3

1 reference

https://api.crossref.org/works/10.1016/0304-419X(77)90001-4

14 December 2022

4

29

366

Labow

1969

1 reference

https://api.crossref.org/works/10.1016/0304-419X(77)90001-4

THE METABOLIC BASIS OF MEGALOBLASTIC ERYTHROPOIESIS

14 December 2022

8

1 reference

https://api.crossref.org/works/10.1016/0304-419X(77)90001-4

On the nature of thymineless death

14 December 2022

9

1 reference

https://api.crossref.org/works/10.1016/0304-419X(77)90001-4

Protein synthesis and RNA turnover in a pyrimidine-deficient bacterium

14 December 2022

10

1 reference

https://api.crossref.org/works/10.1016/0304-419X(77)90001-4

Fluorinated pyrimidines, a new class of tumour-inhibitory compounds

14 December 2022

11

1 reference

https://api.crossref.org/works/10.1016/0304-419X(77)90001-4

14 December 2022

12

23

1226

Heidelberger

1963

1 reference

https://api.crossref.org/works/10.1016/0304-419X(77)90001-4

14 December 2022

13

14

119

Rutman

1954

1 reference

https://api.crossref.org/works/10.1016/0304-419X(77)90001-4

14 December 2022

14

18

329

Danneberg

1958

1 reference

https://api.crossref.org/works/10.1016/0304-419X(77)90001-4

14 December 2022

20

1

14

Reyes

1965

1 reference

https://api.crossref.org/works/10.1016/0304-419X(77)90001-4

Bacteriophage-coded thymidylate synthetase: characteristics of the T4 and T5 enzymes

14 December 2022

22

1 reference

https://api.crossref.org/works/10.1016/0304-419X(77)90001-4

Biochemical determinants of 5-fluorouracil response in vivo. The role of deoxyuridylate pool expansion

14 December 2022

23

1 reference

https://api.crossref.org/works/10.1016/0304-419X(77)90001-4

Thymidylate synthetase from amethopterin- resistant Lactobacillus casei

14 December 2022

24

1 reference

https://api.crossref.org/works/10.1016/0304-419X(77)90001-4

14 December 2022

26

34

2682

Myers

1974

1 reference

https://api.crossref.org/works/10.1016/0304-419X(77)90001-4

14 December 2022

27

18

335

Bosch

1958

1 reference

https://api.crossref.org/works/10.1016/0304-419X(77)90001-4

Thymidylate synthetase: mechanism of inhibition by 5-fluoro-2'-deoxyuridylate.

14 December 2022

29

1 reference

https://api.crossref.org/works/10.1016/0304-419X(77)90001-4

Model studies of thymidylate synthetase. Neighboring-group facilitation of electrophilic substitution reactions of uracil furanosides

14 December 2022

32

1 reference

https://api.crossref.org/works/10.1016/0304-419X(77)90001-4

Structures of reversible and irreversible complexes of thymidylate synthetase and fluorinated pyrimidine nucleotides.

14 December 2022

35

1 reference

https://api.crossref.org/works/10.1016/0304-419X(77)90001-4

Mechanism of interaction of thymidylate synthetase with 5-fluorodeoxyuridylate.

14 December 2022

37

1 reference

https://api.crossref.org/works/10.1016/0304-419X(77)90001-4

On the structure of the cofactor in the complex formed with thymidylate synthetase, 5,10-methylenetetrahy-drofolate and 5-fluoro-2'-deoxyuridylate

14 December 2022

38

1 reference

https://api.crossref.org/works/10.1016/0304-419X(77)90001-4

Model studies of the thymidylate synthetase reaction. Nucleophilic displacement of 5-p-nitrophenoxymethyluracils.

14 December 2022

40

1 reference

https://api.crossref.org/works/10.1016/0304-419X(77)90001-4

Chemistry and enzymology of kcat inhibitors

14 December 2022

41

1 reference

https://api.crossref.org/works/10.1016/0304-419X(77)90001-4

Purification and amino acid analysis of an active site peptide from thymidylate synthetase containing covalently bound 5-fluoro-2'-deoxyuridylate and methylenetetrahydrofolate.

14 December 2022

42

1 reference

https://api.crossref.org/works/10.1016/0304-419X(77)90001-4

Thymidylate synthetase: fluorine-19 nmr characterization of the active site peptide covalently bound to 5-fluoro-2'-deoxyuridylate and 5,10-methylenetetrahydrofolate

14 December 2022

43

1 reference

https://api.crossref.org/works/10.1016/0304-419X(77)90001-4

The interconversion of serine and glycine: role of pteroylglutamic acid and other cofactors

14 December 2022

45

1 reference

https://api.crossref.org/works/10.1016/0304-419X(77)90001-4

Journal of Biological Chemistry

14 December 2022

46

241

5831

Kallen

1966

1 reference

https://api.crossref.org/works/10.1016/0304-419X(77)90001-4

Purification and properties of T2 bacteriophage-induced thymidylate synthetase

14 December 2022

47

1 reference

https://api.crossref.org/works/10.1016/0304-419X(77)90001-4

Inhibition of thymidylate synthetase by showdomycin and its 5′-phosphate

14 December 2022

48

1 reference

https://api.crossref.org/works/10.1016/0304-419X(77)90001-4

Glutathione-catalyzed hydrogen isotope exchange at position 5 of uridine. A model for enzymic carbon alkylation reactions of pyrimidines

14 December 2022

49

1 reference

https://api.crossref.org/works/10.1016/0304-419X(77)90001-4

Effect of amines on the bisulfite-catalyzed hydrogen isotope exchange at the 5 position of uridine

14 December 2022

50

1 reference

https://api.crossref.org/works/10.1016/0304-419X(77)90001-4

A sulfhydryl group is not the covalent catalyst in the thymidylate synthetase reaction

14 December 2022

51

1 reference

https://api.crossref.org/works/10.1016/0304-419X(77)90001-4

The effect of raney nickel on the covalent thymidylate synthetase-5-fluoro-2'-deoxyuridylate-5,10-methylenetetrahydrofolate complex

14 December 2022

53

1 reference

https://api.crossref.org/works/10.1016/0304-419X(77)90001-4

Thymidylate synthetase: studies on peptide containing covalently bound 5-fluoro-2'-deoxyuridylate and 5,10-methylenetetrahydrofolate

14 December 2022

55

1 reference

https://api.crossref.org/works/10.1016/0304-419X(77)90001-4

Purification and properties of T2 bacteriophage-induced thymidylate synthetase

14 December 2022

56

1 reference

https://api.crossref.org/works/10.1016/0304-419X(77)90001-4

Thymidylate synthetase from amethopterin- resistant Lactobacillus casei

14 December 2022

57

1 reference

https://api.crossref.org/works/10.1016/0304-419X(77)90001-4

Characterization of the subunits of thymidylate synthetase

14 December 2022

59

1 reference

https://api.crossref.org/works/10.1016/0304-419X(77)90001-4

14 December 2022

64

3

370

Slavik

1967

1 reference

https://api.crossref.org/works/10.1016/0304-419X(77)90001-4

Syntheses of 5-Trifluoromethyluracil and 5-Trifluoromethyl-2″-Deoxyuridine

14 December 2022

65

1 reference

https://api.crossref.org/works/10.1016/0304-419X(77)90001-4

FLUORINATED PYRIMIDINES. XIX. SOME BIOLOGICAL EFFECTS OF 5-TRIFLUOROMETHYLURACIL AND 5-TRIFLUOROMETHYL-2'-DEOXYURIDINE ON ESCHERICHIA COLI AND BACTERIOPHAGE T4B

14 December 2022

66

1 reference

https://api.crossref.org/works/10.1016/0304-419X(77)90001-4

THERAPEUTIC ANTIVIRAL ACTION OF 5-TRIFLUOROMETHYL-2'-DEOXYURIDINE IN HERPES SIMPLEX KERATITIS.

14 December 2022

67

1 reference

https://api.crossref.org/works/10.1016/0304-419X(77)90001-4

In vivo studies with antiviral agents

14 December 2022

68

1 reference

https://api.crossref.org/works/10.1016/0304-419X(77)90001-4

14 December 2022

69

24

1979

Heidelberger

1964

1 reference

https://api.crossref.org/works/10.1016/0304-419X(77)90001-4

Effects of 5-trifluoromethyldeoxyuridine upon deoxythymidine kinase

14 December 2022

72

1 reference

https://api.crossref.org/works/10.1016/0304-419X(77)90001-4

SYNTHESES OF 5-TRIFLUOROMETHYLURACIL AND 5-TRIFLUOROMETHYL-2'-DEOXYURIDINE.

14 December 2022

73

1 reference

https://api.crossref.org/works/10.1016/0304-419X(77)90001-4

Thymidylate synthetase. Model studies of inhibition by 5-trifluoromethyl-2'-deoxyuridylic acid

14 December 2022

74

1 reference

https://api.crossref.org/works/10.1016/0304-419X(77)90001-4

Inhibition of thymidylate synthetase by 5-formyl- and 5-hydroxymethyl-2′-deoxyuridylate

14 December 2022

75

1 reference

https://api.crossref.org/works/10.1016/0304-419X(77)90001-4

Irreversible inhibition of thymidylate synthetase by 5-formyl-2'-deoxyuridylic acid

14 December 2022

76

1 reference

https://api.crossref.org/works/10.1016/0304-419X(77)90001-4

14 December 2022

77

6

621

Kalman

1970

1 reference

https://api.crossref.org/works/10.1016/0304-419X(77)90001-4

Letter: 5-iodoacetamidomethyl-2'-deoxyuridine 5'-phosphate. A selective inhibitor of mammalian thymidylate synthetases

14 December 2022

78

1 reference

https://api.crossref.org/works/10.1016/0304-419X(77)90001-4

14 December 2022

82

22

600

Friedkin

1962

1 reference

https://api.crossref.org/works/10.1016/0304-419X(77)90001-4

14 December 2022

83

26

2374

Mead

1966

1 reference

https://api.crossref.org/works/10.1016/0304-419X(77)90001-4

Further Evaluation of the Antitumor Activity of Homofolate and its Reduced Derivatives against Methotrexate-Insensitive Tumors

14 December 2022

84

1 reference

https://api.crossref.org/works/10.1016/0304-419X(77)90001-4

14 December 2022

85

1 reference

https://api.crossref.org/works/10.1016/0304-419X(77)90001-4

14 December 2022

89

6

573

Bird

1970

1 reference

https://api.crossref.org/works/10.1016/0304-419X(77)90001-4

14 December 2022

90

10

194

Carlin

1974

1 reference

https://api.crossref.org/works/10.1016/0304-419X(77)90001-4

Thymidylate synthetase from Diplococcus pneumoniae properties and inhibition by folate analogs

14 December 2022

91

1 reference

https://api.crossref.org/works/10.1016/0304-419X(77)90001-4

14 December 2022

Identifiers

1 reference

8 August 2017

1 reference