Accelerated fracture healing in mice lacking the 5-lipoxygenase gene (Q35550092)

8 August 2017

Accelerated fracture healing in mice lacking the 5-lipoxygenase gene (English)

1 reference

8 August 2017

1 reference

Michaele B Manigrasso

series ordinal

1

1 reference

PubMed ID

21067431

8 August 2017

J Patrick O'Connor

series ordinal

2

1 reference

8 August 2017

11 November 2010

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8 August 2017

1 reference

8 August 2017

81

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8 August 2017

6

1 reference

8 August 2017

748-755

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Modulation of the inflammatory response for enhanced bone tissue regeneration

8 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216088

Biosynthesis and metabolism of leukotrienes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216088

The shunt from the cyclooxygenase to lipoxygenase pathway in human osteoarthritic subchondral osteoblasts is linked with a variable expression of the 5-lipoxygenase-activating protein

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216088

Partnering between monomers of cyclooxygenase-2 homodimers

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216088

Cyclooxygenase isozymes: the biology of prostaglandin synthesis and inhibition.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216088

Prostaglandin E2 receptor (EP4) selective agonist (ONO-4819.CD) accelerates bone repair of femoral cortex after drill-hole injury associated with local upregulation of bone turnover in mature rats

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216088

An EP2 receptor-selective prostaglandin E 2 agonist induces bone healing

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216088

Cyclooxygenase-2 regulates mesenchymal cell differentiation into the osteoblast lineage and is critically involved in bone repair

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216088

Cyclooxygenase 2- and prostaglandin E(2) receptor EP(2)-dependent angiogenesis in Apc(Delta716) mouse intestinal polyps

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216088

Mammalian phospholipases A(2): mediators of inflammation, proliferation and apoptosis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216088

Prostaglandins and bone: physiology and pathophysiology

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216088

Rofecoxib [Vioxx, MK-0966; 4-(4'-methylsulfonylphenyl)-3-phenyl-2-(5H)-furanone]: a potent and orally active cyclooxygenase-2 inhibitor. Pharmacological and biochemical profiles

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216088

Pharmacological analysis of cyclooxygenase-1 in inflammation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216088

Cloning and expression in Escherichia coli of the recombinant his-tagged DNA polymerases from Pyrococcus furiosus and Pyrococcus woesei.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216088

5-Lipoxygenase metabolites inhibit bone formation in vitro

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216088

Role of the 5-lipoxygenase-activating protein (FLAP) in murine acute inflammatory responses

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216088

Effects of prostaglandins on deoxyribonucleic acid and aggrecan synthesis in the RCJ 3.1C5.18 chondrocyte cell line: role of second messengers

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216088

Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216088

5-Lipoxygenase metabolites of arachidonic acid stimulate isolated osteoclasts to resorb calcified matrices

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216088

Enhanced gastric mucosal leukotriene B4 synthesis in patients taking non-steroidal anti-inflammatory drugs

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216088

5-Lipoxygenase: enzyme expression and regulation of activity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216088

A natural disruption of the secretory group II phospholipase A2 gene in inbred mouse strains

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216088

Measurement of protein using bicinchoninic acid

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216088

Role of leukotrienes revealed by targeted disruption of the 5-lipoxygenase gene.

12 July 2018

1 reference

https://api.crossref.org/works/10.3109%2F17453674.2010.533931

Differential regulation of EP receptor isoforms during chondrogenesis and chondrocyte maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F17453674.2010.533931

Pharmacological inhibition of 5-lipoxygenase accelerates and enhances fracture-healing

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F17453674.2010.533931

Analgesic effects of p38 kinase inhibitor treatment on bone fracture healing.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F17453674.2010.533931

Avian osteoclast cells are stimulated to resorb calcified matrices by and possess receptors for leukotriene B4.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F17453674.2010.533931

Chondrogenesis of expanded adult human articular chondrocytes is enhanced by specific prostaglandins

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F17453674.2010.533931

Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F17453674.2010.533931

A novel, non-prostanoid EP2 receptor-selective prostaglandin E2 agonist stimulates local bone formation and enhances fracture healing

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F17453674.2010.533931

Characterization of a closed femur fracture model in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F17453674.2010.533931

Regulation of the expression of 5-lipoxygenase-activating protein/5-lipoxygenase and the synthesis of leukotriene B(4) in osteoarthritic chondrocytes: role of transforming growth factor beta and eicosanoids

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F17453674.2010.533931

Cyclo-oxygenase 2 function is essential for bone fracture healing

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F17453674.2010.533931

Dose and time-dependent effects of cyclooxygenase-2 inhibition on fracture-healing.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F17453674.2010.533931

Primary murine limb bud mesenchymal cells in long-term culture complete chondrocyte differentiation: TGF-beta delays hypertrophy and PGE2 inhibits terminal differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F17453674.2010.533931

Leukotriene and prostaglandin synthesis pathways in osteoarthritic synovial membranes: regulating factors for interleukin 1beta synthesis.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216088

Heterotopic ossification prophylaxis with indomethacin increases the risk of long-bone nonunion.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216088

26 September 2018

PGE2 and angiogenesis

1 reference

12 December 2020

Changes in tissue concentration of prostaglandins during endochondral bone differentiation

1 reference

12 December 2020

An improved method for preparing histological sections of metallic implants

1 reference

12 December 2020

Effects of leukotrienes on osteoblastic cell proliferation

1 reference

12 December 2020

Mice lacking 5-lipoxygenase have increased cortical bone thickness

1 reference

12 December 2020

Osteopenia and impaired fracture healing in aged EP4 receptor knockout mice

1 reference

12 December 2020

Genetic model of selective COX2 inhibition reveals novel heterodimer signaling

1 reference

12 December 2020

Comparison of fracture healing among different inbred mouse strains

1 reference

12 December 2020

Leukotriene B4 stimulates osteoclastic bone resorption both in vitro and in vivo

1 reference

12 December 2020

10.3109/17453674.2010.533931

Identifiers

DOI

1 reference

8 August 2017

1 reference

8 August 2017

1 reference

PubMed ID

21067431