A role for PACE4 in the proteolytic activation of anthrax toxin protective antigen. (Q35553323)

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4 November 2019

title

A role for PACE4 in the proteolytic activation of anthrax toxin protective antigen (English)

1 reference

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4 November 2019

1 reference

3

Leppla SH

2 references

8 August 2017

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4 November 2019

author name string

Gordon VM

series ordinal

1

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4 November 2019

Rehemtulla A

series ordinal

2

1 reference

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4 November 2019

language of work or name

English

0 references

publication date

1 August 1997

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4 November 2019

published in

Infection and Immunity

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4 November 2019

volume

65

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4 November 2019

issue

8

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4 November 2019

page(s)

3370-3375

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Mammalian paired basic amino acid convertases of prohormones and proproteins

4 November 2019

cites work

1 reference

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Structure and function of eukaryotic proprotein processing enzymes of the subtilisin family of serine proteases.

12 July 2018

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Expression of mouse furin in a Chinese hamster cell resistant to Pseudomonas exotoxin A and viruses complements the genetic lesion.

12 July 2018

1 reference

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Proteolytic activation of bacterial toxins: role of bacterial and host cell proteases

12 July 2018

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Differential processing of proenkephalin by prohormone convertases 1(3) and 2 and furin

12 July 2018

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Evidence for involvement of furin in cleavage and activation of diphtheria toxin

12 July 2018

1 reference

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PACE4 is a member of the mammalian propeptidase family that has overlapping but not identical substrate specificity to PACE

12 July 2018

1 reference

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The tissue distribution of mRNAs for the PACE4 isoforms, kexin-like processing protease: PACE4C and PACE4D mRNAs are major transcripts among PACE4 isoforms

12 July 2018

1 reference

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Cleavage of pseudomonas exotoxin and diphtheria toxin by a furin-like enzyme prepared from beef liver

12 July 2018

1 reference

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The cytoplasmic domain mediates localization of furin to the trans-Golgi network en route to the endosomal/lysosomal system.

12 July 2018

1 reference

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Proteolytic activation of bacterial toxins by eukaryotic cells is performed by furin and by additional cellular proteases

12 July 2018

1 reference

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Two independent targeting signals in the cytoplasmic domain determine trans-Golgi network localization and endosomal trafficking of the proprotein convertase furin

12 July 2018

1 reference

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Intracellular trafficking and activation of the furin proprotein convertase: localization to the TGN and recycling from the cell surface

12 July 2018

1 reference

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Mammalian subtilisins: the long-sought dibasic processing endoproteases

12 July 2018

1 reference

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Functional mapping of anthrax toxin lethal factor by in-frame insertion mutagenesis.

12 July 2018

1 reference

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Identification of a Second Human Subtilisin-Like Protease Gene in thefes/fpsRegion of Chromosome 15

12 July 2018

1 reference

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Characterization of a cellular protease that cleaves Pseudomonas exotoxin

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175476

Fusions of anthrax toxin lethal factor to the ADP-ribosylation domain of Pseudomonas exotoxin A are potent cytotoxins which are translocated to the cytosol of mammalian cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175476

Expression cloning of a diphtheria toxin receptor: identity with a heparin-binding EGF-like growth factor precursor.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175476

Preferred sequence requirements for cleavage of pro-von Willebrand factor by propeptide-processing enzymes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175476

Anthrax toxin protective antigen is activated by a cell surface protease with the sequence specificity and catalytic properties of furin

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175476

Production and purification of anthrax toxin

12 July 2018

1 reference

12 December 2020

Proprotein processing activity and cleavage site selectivity of the Kex2-like endoprotease PACE4

1 reference

12 December 2020

Furin activates Pseudomonas exotoxin A by specific cleavage in vivo and in vitro

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12 December 2020

A deleted variant of Bacillus anthracis protective antigen is non-toxic and blocks anthrax toxin action in vivo

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12 December 2020

Identifiers

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9234799%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

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