Integrated genomic analysis of relapsed childhood acute lymphoblastic leukemia reveals therapeutic strategies (Q35553581)

8 August 2017

title

Integrated genomic analysis of relapsed childhood acute lymphoblastic leukemia reveals therapeutic strategies (English)

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8 August 2017

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lymphoblastic leukemia

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8

Stephen P Hunger

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8 August 2017

10

Richard Saffery

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ORCID Public Data File 2021

8 August 2017

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author name string

Laura E Hogan

1

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Julia A Meyer

2

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Jun Yang

3

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Jinhua Wang

4

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Nicholas Wong

5

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Wenjian Yang

6

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8 August 2017

Gregory Condos

7

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8 August 2017

Elizabeth Raetz

9

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Mary V Relling

11

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8 August 2017

Deepa Bhojwani

12

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Debra J Morrison

13

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William L Carroll

14

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8 August 2017

language of work or name

English

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publication date

14 September 2011

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8 August 2017

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8 August 2017

volume

118

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8 August 2017

issue

19

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8 August 2017

page(s)

5218-5226

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Endogenous knockdown of survivin improves chemotherapeutic response in ALL models

8 August 2017

cites work

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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Specific promoter methylation identifies different subgroups of MLL-rearranged infant acute lymphoblastic leukemia, influences clinical outcome, and provides therapeutic options

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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Acquired variation outweighs inherited variation in whole genome analysis of methotrexate polyglutamate accumulation in leukemia

12 July 2018

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Genomic analysis of the clonal origins of relapsed acute lymphoblastic leukemia.

12 July 2018

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PTPROt inactivates the oncogenic fusion protein BCR/ABL and suppresses transformation of K562 cells

12 July 2018

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Genome-wide copy number profiling reveals molecular evolution from diagnosis to relapse in childhood acute lymphoblastic leukemia

12 July 2018

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Genome-wide identification of aberrantly methylated promoter associated CpG islands in acute lymphocytic leukemia.

12 July 2018

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Methylation and silencing of protein tyrosine phosphatase receptor type O in chronic lymphocytic leukemia

12 July 2018

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12 July 2018

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Epigenetic regulation of Wnt-signaling pathway in acute lymphoblastic leukemia

12 July 2018

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Biologic pathways associated with relapse in childhood acute lymphoblastic leukemia: a Children's Oncology Group study

12 July 2018

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FoxM1B is overexpressed in human glioblastomas and critically regulates the tumorigenicity of glioma cells

12 July 2018

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APC inhibits ERK pathway activation and cellular proliferation induced by RAS

12 July 2018

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Epigenetic inactivation and aberrant transcription of CSMD1 in squamous cell carcinoma cell lines

12 July 2018

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Protein tyrosine phosphatase receptor-type O (PTPRO) exhibits characteristics of a candidate tumor suppressor in human lung cancer

12 July 2018

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Convergence of Wnt, beta-catenin, and cadherin pathways

12 July 2018

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Suppression of the protein tyrosine phosphatase receptor type O gene (PTPRO) by methylation in hepatocellular carcinomas

12 July 2018

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DNA microarrays for comparison of gene expression profiles between diagnosis and relapse in precursor-B acute lymphoblastic leukemia: choice of technique and purification influence the identification of potential diagnostic markers.

12 July 2018

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Critical role of histone methylation in tumor suppressor gene silencing in colorectal cancer.

12 July 2018

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Transcript map of the 8p23 putative tumor suppressor region

12 July 2018

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Expression of dominant-negative and mutant isoforms of the antileukemic transcription factor Ikaros in infant acute lymphoblastic leukemia

12 July 2018

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Ribonucleotide reductase R2 gene expression and changes in drug sensitivity and genome stability

12 July 2018

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Epigenetic silencing of BIM in glucocorticoid poor-responsive pediatric acute lymphoblastic leukemia, and its reversal by histone deacetylase inhibition.

12 July 2018

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Genome-wide expression analysis of paired diagnosis-relapse samples in ALL indicates involvement of pathways related to DNA replication, cell cycle and DNA repair, independent of immune phenotype.

26 September 2018

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DNA methylation for subtype classification and prediction of treatment outcome in patients with childhood acute lymphoblastic leukemia.

26 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217405

Mutation of genes affecting the RAS pathway is common in childhood acute lymphoblastic leukemia.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217405

Outcome after relapse among children with standard-risk acute lymphoblastic leukemia: Children's Oncology Group study CCG-1952.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217405

High-resolution genomic profiling of childhood ALL reveals novel recurrent genetic lesions affecting pathways involved in lymphocyte differentiation and cell cycle progression.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217405

The gene expression signature of relapse in paediatric acute lymphoblastic leukaemia: implications for mechanisms of therapy failure.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217405

Acute lymphoblastic leukemia with TEL-AML1 fusion has lower expression of genes involved in purine metabolism and lower de novo purine synthesis

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217405

In vitro cellular drug resistance in children with relapsed/refractory acute lymphoblastic leukemia

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217405

BCR–ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217405

Homozygous deletion of CDKN2A (p16, p14) and CDKN2B (p15) genes is a poor prognostic factor in adult but not in childhood B-lineage acute lymphoblastic leukemia: a comparative deletion and hypermethylation study

15 November 2018

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12 December 2020

The DNA methylome of pediatric acute lymphoblastic leukemia

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12 December 2020

A 10-gene classifier for distinguishing head and neck squamous cell carcinoma and lung squamous cell carcinoma

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12 December 2020

Outcome after first relapse in children with acute lymphoblastic leukemia: a report based on the Dutch Childhood Oncology Group (DCOG) relapse all 98 protocol

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12 December 2020

10.1182/BLOOD-2011-04-345595

Identifiers

DOI

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8 August 2017

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8 August 2017

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