Anti-IL6-receptor-alpha (tocilizumab) does not inhibit human monocyte-derived dendritic cell maturation or alloreactive T-cell responses (Q35553632)

8 August 2017

title

Anti-IL6-receptor-alpha (tocilizumab) does not inhibit human monocyte-derived dendritic cell maturation or alloreactive T-cell responses (English)

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8 August 2017

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Brian C Betts

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8 August 2017

Erin T St Angelo

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2

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8 August 2017

Michael Kennedy

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3

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8 August 2017

James W Young

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4

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8 August 2017

language of work or name

English

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publication date

22 September 2011

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8 August 2017

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8 August 2017

volume

118

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8 August 2017

issue

19

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8 August 2017

page(s)

5340-5343

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Tocilizumab for the treatment of steroid refractory graft-versus-host disease

8 August 2017

cites work

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217414

Th17 and regulatory T cells in mediating and restraining inflammation

27 July 2018

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Tocilizumab in systemic lupus erythematosus: data on safety, preliminary efficacy, and impact on circulating plasma cells from an open-label phase I dosage-escalation study

27 July 2018

1 reference

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Blockade of interleukin-6 signaling augments regulatory T-cell reconstitution and attenuates the severity of graft-versus-host disease.

27 July 2018

1 reference

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Comparison of tocilizumab monotherapy versus methotrexate monotherapy in patients with moderate to severe rheumatoid arthritis: the AMBITION study

27 July 2018

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27 July 2018

1 reference

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Dendritic cells and cytokines in human inflammatory and autoimmune diseases

27 July 2018

1 reference

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Foxp3 in control of the regulatory T cell lineage

27 July 2018

1 reference

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CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells

27 July 2018

1 reference

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TGF-beta1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cells

27 July 2018

1 reference

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Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3

27 July 2018

1 reference

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Differential CD52 expression by distinct myeloid dendritic cell subsets: implications for alemtuzumab activity at the level of antigen presentation in allogeneic graft-host interactions in transplantation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217414

Human blood dendritic cells selectively express CD83, a member of the immunoglobulin superfamily.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217414

IL-6 enhances the generation of cytolytic T lymphocytes in the allogeneic mixed leucocyte reaction

27 July 2018

1 reference

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Janus kinase-2 inhibition induces durable tolerance to alloantigen by human dendritic cell-stimulated T cells yet preserves immunity to recall antigen

27 July 2018

1 reference

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Interleukin-6 Modulates Graft-versus-Host Responses after Experimental Allogeneic Bone Marrow Transplantation

26 September 2018

1 reference

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TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function

26 September 2018

1 reference

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Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells

26 September 2018

1 reference

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Human dendritic cells: potent antigen-presenting cells at the crossroads of innate and adaptive immunity

26 September 2018

1 reference

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Selective recruitment of immature and mature dendritic cells by distinct chemokines expressed in different anatomic sites

26 September 2018

1 reference

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Blockade of interleukin 6 trans signaling suppresses T-cell resistanceagainst apoptosis in chronic intestinal inflammation: Evidence in Crohn diseaseand experimental colitis in vivo

26 September 2018

1 reference

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Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells

15 November 2018

1 reference

12 December 2020

Mature Human Langerhans Cells Derived from CD34+ Hematopoietic Progenitors Stimulate Greater Cytolytic T Lymphocyte Activity in the Absence of Bioactive IL-12p70, by Either Single Peptide Presentation or Cross-Priming, Than Do Dermal-Interstitial or

1 reference

12 December 2020

Pro-inflammatory cytokines and prostaglandins induce maturation of potent immunostimulatory dendritic cells under fetal calf serum-free conditions

1 reference

12 December 2020

Effectiveness and safety of tocilizumab, an anti-interleukin-6 receptor monoclonal antibody, in a patient with refractory GI graft-versus-host disease

1 reference

12 December 2020

10.1182/BLOOD-2011-06-363390

Identifiers

DOI

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8 August 2017

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8 August 2017

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