DNA polymerase stabilization at stalled replication forks requires Mec1 and the RecQ helicase Sgs1. (Q35561531)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12912929%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

title

DNA polymerase stabilization at stalled replication forks requires Mec1 and the RecQ helicase Sgs1 (English)

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6 November 2019

5

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6 November 2019

author name string

Jennifer A Cobb

1

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6 November 2019

Lotte Bjergbaek

2

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6 November 2019

Kenji Shimada

3

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6 November 2019

Christian Frei

4

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6 November 2019

language of work or name

English

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publication date

1 August 2003

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6 November 2019

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6 November 2019

volume

22

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6 November 2019

issue

16

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6 November 2019

page(s)

4325-4336

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The yeast Sgs1 helicase is differentially required for genomic and ribosomal DNA replication

6 November 2019

cites work

1 reference

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An ATR- and Cdc7-dependent DNA damage checkpoint that inhibits initiation of DNA replication

12 July 2018

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ORC and the intra-S-phase checkpoint: a threshold regulates Rad53p activation in S phase

12 July 2018

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Checking on the fork: the DNA-replication stress-response pathway

12 July 2018

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Homologous recombination resolution defect in werner syndrome

12 July 2018

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Fork reversal and ssDNA accumulation at stalled replication forks owing to checkpoint defects

12 July 2018

1 reference

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A single unbranched S-phase DNA damage and replication fork blockage checkpoint pathway

12 July 2018

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Suppression of genome instability by redundant S-phase checkpoint pathways in Saccharomyces cerevisiae

12 July 2018

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A unified view of the DNA-damage checkpoint

12 July 2018

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Systematic genetic analysis with ordered arrays of yeast deletion mutants

12 July 2018

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Two checkpoint complexes are independently recruited to sites of DNA damage in vivo

12 July 2018

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The DNA replication checkpoint response stabilizes stalled replication forks

12 July 2018

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Regulation of DNA replication fork progression through damaged DNA by the Mec1/Rad53 checkpoint

12 July 2018

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Functions of RecQ family helicases: possible involvement of Bloom's and Werner's syndrome gene products in guarding genome integrity during DNA replication

12 July 2018

1 reference

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Is the MCM2-7 complex the eukaryotic DNA replication fork helicase?

12 July 2018

1 reference

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SGS1, the Saccharomyces cerevisiae homologue of BLM and WRN, suppresses genome instability and homeologous recombination

12 July 2018

1 reference

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Phosphorylation of the replication protein A large subunit in the Saccharomyces cerevisiae checkpoint response

12 July 2018

1 reference

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Cell cycle regulation of the endogenous wild type Bloom's syndrome DNA helicase

12 July 2018

1 reference

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Dpb11 controls the association between DNA polymerases alpha and epsilon and the autonomously replicating sequence region of budding yeast

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175781

RecQ family helicases: roles in cancer and aging

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175781

The yeast Sgs1p helicase acts upstream of Rad53p in the DNA replication checkpoint and colocalizes with Rad53p in S-phase-specific foci

12 July 2018

1 reference

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Activation of Rad53 kinase in response to DNA damage and its effect in modulating phosphorylation of the lagging strand DNA polymerase.

12 July 2018

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Three new dominant drug resistance cassettes for gene disruption in Saccharomyces cerevisiae

12 July 2018

1 reference

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A role for the Cdc7 kinase regulatory subunit Dbf4p in the formation of initiation-competent origins of replication

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175781

Differential assembly of Cdc45p and DNA polymerases at early and late origins of DNA replication

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175781

Analysis of the essential functions of the C-terminal protein/protein interaction domain of Saccharomyces cerevisiae pol epsilon and its unexpected ability to support growth in the absence of the DNA polymerase domain

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175781

Functional and physical interaction between WRN helicase and human replication protein A

12 July 2018

1 reference

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Relocalization of telomeric Ku and SIR proteins in response to DNA strand breaks in yeast

12 July 2018

1 reference

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DNA polymerase epsilon catalytic domains are dispensable for DNA replication, DNA repair, and cell viability

12 July 2018

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A Mec1- and Rad53-dependent checkpoint controls late-firing origins of DNA replication

12 July 2018

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A suppressor of two essential checkpoint genes identifies a novel protein that negatively affects dNTP pools

12 July 2018

1 reference

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Recovery from DNA replicational stress is the essential function of the S-phase checkpoint pathway

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175781

Association of RPA with chromosomal replication origins requires an Mcm protein, and is regulated by Rad53, and cyclin- and Dbf4-dependent kinases

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175781

Bloom's and Werner's syndrome genes suppress hyperrecombination in yeast sgs1 mutant: implication for genomic instability in human diseases

12 July 2018

1 reference

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Purification and characterization of the Sgs1 DNA helicase activity of Saccharomyces cerevisiae.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175781

Role of Schizosaccharomyces pombe RecQ homolog, recombination, and checkpoint genes in UV damage tolerance

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175781

rqh1+, a fission yeast gene related to the Bloom's and Werner's syndrome genes, is required for reversible S phase arrest

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175781

RAD9, RAD17, and RAD24 are required for S phase regulation in Saccharomyces cerevisiae in response to DNA damage.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175781

The ATM homologue MEC1 is required for phosphorylation of replication protein A in yeast

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175781

SGS1, a homologue of the Bloom's and Werner's syndrome genes, is required for maintenance of genome stability in Saccharomyces cerevisiae

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175781

Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175781

Time of replication of ARS elements along yeast chromosome III.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175781

RecQ helicases and genome stability: lessons from model organisms and human disease.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175781

ATR homolog Mec1 promotes fork progression, thus averting breaks in replication slow zones.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175781

Replication dynamics of the yeast genome.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175781

A checkpoint regulates the rate of progression through S phase in S. cerevisiae in response to DNA damage.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175781

Importance of the Sgs1 helicase activity in DNA repair of Saccharomyces cerevisiae

26 September 2018

1 reference

12 December 2020

Elevation of sister chromatid exchange in Saccharomyces cerevisiae sgs1 disruptants and the relevance of the disruptants as a system to evaluate mutations in Bloom's syndrome gene

1 reference

12 December 2020

Homologous recombination is responsible for cell death in the absence of the Sgs1 and Srs2 helicases

1 reference

12 December 2020

Recruitment of Mec1 and Ddc1 checkpoint proteins to double-strand breaks through distinct mechanisms

1 reference

12 December 2020

Regulation of DNA-replication origins during cell-cycle progression

1 reference

12 December 2020

Human homologues of yeast helicase

1 reference

12 December 2020

Bloom's syndrome gene suppresses premature ageing caused by Sgs1 deficiency in yeast

1 reference

12 December 2020

Identifiers

DOI

10.1093/EMBOJ/CDG391

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12912929%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12912929%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

1 reference