A signalling role for 4-hydroxy-2-nonenal in regulation of mitochondrial uncoupling. (Q35561876)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12912909%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

title

A signalling role for 4-hydroxy-2-nonenal in regulation of mitochondrial uncoupling (English)

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6 November 2019

2

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6 November 2019

Reinald Pamplona

7

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6 November 2019

Antonio Vidal-Puig

8

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6 November 2019

Martin D. Brand

11

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6 November 2019

1

Karim S Echtay

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6 November 2019

author name string

Julian L Pakay

3

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6 November 2019

Mika B Jekabsons

4

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6 November 2019

Adrian J Lambert

5

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6 November 2019

Manuel Portero-Otín

6

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6 November 2019

Steven Wang

9

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6 November 2019

Stephen J Roebuck

10

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6 November 2019

language of work or name

English

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publication date

1 August 2003

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6 November 2019

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6 November 2019

volume

22

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6 November 2019

page(s)

4103-4110

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6 November 2019

issue

16

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Superoxide activates mitochondrial uncoupling protein 2 from the matrix side. Studies using targeted antioxidants

6 November 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175801

Topology of superoxide production from different sites in the mitochondrial electron transport chain

12 July 2018

1 reference

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Oxidative damage and phospholipid fatty acyl composition in skeletal muscle mitochondria from mice underexpressing or overexpressing uncoupling protein 3.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175801

Mitochondrial uncoupling as a target for drug development for the treatment of obesity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175801

Identification of bovine heart cytochrome c oxidase subunits modified by the lipid peroxidation product 4-hydroxy-2-nonenal

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175801

Nucleotide binding to human uncoupling protein-2 refolded from bacterial inclusion bodies

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175801

No evidence for a basal, retinoic, or superoxide-induced uncoupling activity of the uncoupling protein 2 present in spleen or lung mitochondria.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175801

Superoxide activates mitochondrial uncoupling proteins

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175801

The basal proton conductance of skeletal muscle mitochondria from transgenic mice overexpressing or lacking uncoupling protein-3

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175801

Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, beta cell dysfunction, and type 2 diabetes.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175801

Homologues of the uncoupling protein from brown adipose tissue (UCP1): UCP2, UCP3, BMCP1 and UCP4.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175801

Uncoupling proteins 2 and 3 are highly active H(+) transporters and highly nucleotide sensitive when activated by coenzyme Q (ubiquinone)

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175801

Energy metabolism in uncoupling protein 3 gene knockout mice

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175801

The uncoupling protein homologues: UCP1, UCP2, UCP3, StUCP and AtUCP

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175801

Retinoids activate proton transport by the uncoupling proteins UCP1 and UCP2.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175801

stress sensitive B encodes an adenine nucleotide translocase in Drosophila melanogaster.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175801

Mitochondrial adenine nucleotide translocase is modified oxidatively during aging

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175801

Reactive oxygen species, mitochondria, apoptosis and aging.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175801

Uncoupling protein-3: a new member of the mitochondrial carrier family with tissue-specific expression

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175801

Inhibition of adenine nucleotide translocator by lipid peroxidation products

12 July 2018

1 reference

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Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes

12 July 2018

1 reference

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Selective cleavage of thioether linkage in proteins modified with 4-hydroxynonenal

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175801

A mitochondrial uncoupling artifact can be caused by expression of uncoupling protein 1 in yeast

12 July 2018

1 reference

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Uncoupling protein 2, in vivo distribution, induction upon oxidative stress, and evidence for translational regulation

26 September 2018

1 reference

12 December 2020

Molecular basis of age-dependent changes in the activity of adenine nucleotide translocase

1 reference

12 December 2020

Alterations in mitochondrial membrane fluidity by lipid peroxidation products

1 reference

12 December 2020

A Novel Regulatory Pathway of Brown Fat Thermogenesis

1 reference

12 December 2020

Structural definition of early lysine and histidine adduction chemistry of 4-hydroxynonenal

1 reference

12 December 2020

Chemical characterization of a protein-4-hydroxy-2-nonenal cross-link: immunochemical detection in mitochondria exposed to oxidative stress

1 reference

12 December 2020

Diabetes induces an impairment in the proteolytic activity against oxidized proteins and a heterogeneous effect in nonenzymatic protein modifications in the cytosol of rat liver and kidney

1 reference

12 December 2020

4-Hydroxyhexenal is a potent inducer of the mitochondrial permeability transition

1 reference

12 December 2020

Modulation of matrix Ca2+ content by the ADP/ATP carrier in brown adipose tissue mitochondria. Influence of membrane lipid composition

1 reference

12 December 2020

The effect of the lipid peroxidation product 4-hydroxynonenal and of its metabolite 4-hydroxynonenoic acid on respiration of rat kidney cortex mitochondria

1 reference

12 December 2020

4-hydroxy-2-nonenal-protein adducts and apoptosis in murine lung cells after acute ozone exposure

1 reference

12 December 2020

Inhibition of NADH-linked mitochondrial respiration by 4-hydroxy-2-nonenal

1 reference

12 December 2020

Selective inactivation of alpha-ketoglutarate dehydrogenase and pyruvate dehydrogenase: reaction of lipoic acid with 4-hydroxy-2-nonenal

1 reference

12 December 2020

Identifiers

DOI

10.1093/EMBOJ/CDG412

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12912909%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

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6 November 2019

1 reference