Alcohol metabolism in human cells causes DNA damage and activates the Fanconi anemia-breast cancer susceptibility (FA-BRCA) DNA damage response network (Q35566416)

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scientific article published on 15 September 2011

Language	Label	Description	Also known as
English	Alcohol metabolism in human cells causes DNA damage and activates the Fanconi anemia-breast cancer susceptibility (FA-BRCA) DNA damage response network	scientific article published on 15 September 2011

Statements

scholarly article

1 reference

Europe PubMed Central

8 August 2017

Alcohol metabolism in human cells causes DNA damage and activates the Fanconi anemia-breast cancer susceptibility (FA-BRCA) DNA damage response network (English)

1 reference

Europe PubMed Central

8 August 2017

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2

object named as

Silvia Balbo

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author name string

Jessy Abraham

1

1 reference

Europe PubMed Central

8 August 2017

David Crabb

3

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Europe PubMed Central

8 August 2017

Phillip J Brooks

4

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Europe PubMed Central

8 August 2017

publication date

15 September 2011

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Europe PubMed Central

8 August 2017

Alcoholism: Clinical and Experimental Research

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Europe PubMed Central

8 August 2017

35

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Europe PubMed Central

8 August 2017

12

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Europe PubMed Central

8 August 2017

2113-2120

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Europe PubMed Central

8 August 2017

describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3221806/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Ethanol metabolism by HeLa cells transduced with human alcohol dehydrogenase isoenzymes: control of the pathway by acetaldehyde concentration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221806

12 July 2018

Recruitment of fanconi anemia and breast cancer proteins to DNA damage sites is differentially governed by replication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221806

12 July 2018

How the fanconi anemia pathway guards the genome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221806

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Interaction of the effects of alcohol drinking and polymorphisms in alcohol-metabolizing enzymes on the risk of female breast cancer in Japan

1 reference

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Acetaldehyde stimulates FANCD2 monoubiquitination, H2AX phosphorylation, and BRCA1 phosphorylation in human cells in vitro: implications for alcohol-related carcinogenesis

1 reference

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Acetaldehyde as a common denominator and cumulative carcinogen in digestive tract cancers

1 reference

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The alcohol flushing response: an unrecognized risk factor for esophageal cancer from alcohol consumption

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Increased formation of gastric N(2)-ethylidene-2'-deoxyguanosine DNA adducts in aldehyde dehydrogenase-2 knockout mice treated with ethanol

1 reference

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Alcohol induces DNA damage and the Fanconi anemia D2 protein implicating FANCD2 in the DNA damage response pathways in brain

1 reference

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Emergence of a DNA-damage response network consisting of Fanconi anaemia and BRCA proteins

1 reference

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Overview: how is alcohol metabolized by the body?

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Alcohol metabolism and cancer risk

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Proteasome function is required for DNA damage response and fanconi anemia pathway activation

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Molecular mechanisms of alcohol-mediated carcinogenesis

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Carcinogenicity of alcoholic beverages

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The etiology of alcohol-induced breast cancer

1 reference

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DNA adducts from acetaldehyde: implications for alcohol-related carcinogenesis

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Overview of the role of alcohol dehydrogenase and aldehyde dehydrogenase and their variants in the genesis of alcohol-related pathology

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https://api.crossref.org/works/10.1111%2FJ.1530-0277.2011.01563.X

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Alcohol and cancer

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Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway

1 reference

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High-level expression of rat class I alcohol dehydrogenase is sufficient for ethanol-induced fat accumulation in transduced HeLa cells

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Esophageal cancer and aldehyde dehydrogenase-2 genotypes in Japanese males.

1 reference

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Alcohol and aldehyde dehydrogenase genotypes and alcoholism in Chinese men

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The distribution and metabolism of acetaldehyde in rats during ethanol oxidation-I. The distribution of acetaldehyde in liver, brain, blood and breath.

1 reference

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N2-ethyldeoxyguanosine as a potential biomarker for assessing effects of alcohol consumption on DNA.

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21 January 2018

Immunohistochemical detection of 1,N6-ethenodeoxyadenosine in nuclei of human liver affected by diseases predisposing to hepato-carcinogenesis

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21 January 2018

Increased DNA damage in ALDH2-deficient alcoholics.

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21 January 2018

A review of human carcinogens--Part E: tobacco, areca nut, alcohol, coal smoke, and salted fish

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Establishment of steady-state metabolism of ethanol in perfused rat liver: the quantitative analysis using kinetic mechanism-based rate equations of alcohol dehydrogenase

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21 January 2018

Measurement of acetaldehyde: what levels occur naturally and in response to alcohol?

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Ethanol stimulates proliferation, ERalpha and aromatase expression in MCF-7 human breast cancer cells.

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Class I alcohol dehydrogenase is highly expressed in normal human mammary epithelium but not in invasive breast cancer: implications for breast carcinogenesis.

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26 September 2018

Use of cultured cells in assessing ethanol toxicity and ethanol-related metabolism

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26 September 2018

The Fanconi anemia family of genes and its correlation with breast cancer susceptibility and breast cancer features

1 reference

https://api.crossref.org/works/10.1111%2FJ.1530-0277.2011.01563.X

21 January 2018

Increased formation of hepatic N2-ethylidene-2'-deoxyguanosine DNA adducts in aldehyde dehydrogenase 2-knockout mice treated with ethanol

1 reference

https://pubmed.ncbi.nlm.nih.gov/21919919

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1530-0277.2011.01563.X

1 reference

Europe PubMed Central

8 August 2017

release_syzej6dlzvh2dojgy5z4h7f42a

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https://api.fatcat.wiki/v0/release/syzej6dlzvh2dojgy5z4h7f42a

24 November 2022

based on heuristic

mapped directly with Wikidata item

1 reference

Europe PubMed Central

8 August 2017

1 reference

Europe PubMed Central

8 August 2017

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