Retinoids in cancer therapy and chemoprevention: promise meets resistance (Q35567239)

8 August 2017

1 reference

title

Retinoids in cancer therapy and chemoprevention: promise meets resistance (English)

1 reference

antineoplastic resistance

8 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14576840

24 March 2024

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206936

24 March 2024

3

Ethan Dmitrovsky

1 reference

8 August 2017

1

Sarah J Freemantle

1 reference

8 August 2017

2

Michael J Spinella

1 reference

8 August 2017

Sarah J. Freemantle

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14576840

24 March 2024

language of work or name

English

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publication date

1 October 2003

1 reference

8 August 2017

20 October 2003

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14576840

full work available at URL

24 March 2024

https://www.nature.com/articles/1206936.pdf

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14576840

https://www.nature.com/articles/1206936.pdf

24 March 2024

file format

Portable Document Format

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206936

https://www.nature.com/articles/1206936

24 March 2024

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206936

24 March 2024

1 reference

8 August 2017

22

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8 August 2017

47

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8 August 2017

7305-7315

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1206936

8 August 2017

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cites work

A unique carboxy-terminus truncation mutant of the retinoic acid receptor alpha gene associated with a variant marker chromosome in a retinoic acid resistant HL-60 subline

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A PMLRARalpha transgene initiates murine acute promyelocytic leukemia

21 January 2018

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Direct channeling of retinoic acid between cellular retinoic acid-binding protein II and retinoic acid receptor sensitizes mammary carcinoma cells to retinoic acid-induced growth arrest

21 January 2018

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Differentiating agents in pediatric malignancies: all-trans-retinoic acid and arsenic in acute promyelocytic leukemia

21 January 2018

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21 January 2018

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A transcriptional co-repressor that interacts with nuclear hormone receptors

21 January 2018

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5-Azacytidine and 5-aza-2'-deoxycytidine as inhibitors of DNA methylation: mechanistic studies and their implications for cancer therapy

21 January 2018

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Retinoic acid-induced granulocytic differentiation of HL-60 myeloid leukemia cells is mediated directly through the retinoic acid receptor (RAR-alpha).

21 January 2018

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Retinoic acid activates p53 in human embryonal carcinoma through retinoid receptor-dependent stimulation of p53 transactivation function

21 January 2018

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Retinoic acid-induced cell cycle arrest of human myeloid cell lines is associated with sequential down-regulation of c-Myc and cyclin E and posttranscriptional up-regulation of p27(Kip1).

21 January 2018

1 reference

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Retinoid-induced growth arrest of breast carcinoma cells involves co-activation of multiple growth-inhibitory genes

21 January 2018

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Cyclin proteolysis as a retinoid cancer prevention mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

Transgenic expression of PML/RARalpha impairs myelopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

Ligand induction of a transcriptionally active thyroid hormone receptor coactivator complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

Developmentally-related candidate retinoic acid target genes regulated early during neuronal differentiation of human embryonal carcinoma

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

Retinoic acid resistance in acute promyelocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

Fusion proteins of the retinoic acid receptor-alpha recruit histone deacetylase in promyelocytic leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

Retinoic-acid-induced modulation of c-myc not dependent on its continued presence: possible role in pre-commitment for HL-60 cells

21 January 2018

1 reference

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Inactivation of retinoic acid receptor beta by promoter CpG hypermethylation in gastric cancer

21 January 2018

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Distinct interactions of PML-RARalpha and PLZF-RARalpha with co-repressors determine differential responses to RA in APL.

21 January 2018

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Acute leukemia with promyelocytic features in PML/RARalpha transgenic mice

21 January 2018

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Recent advances in chemoprevention of cancer

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

Tumor-suppressive effect of the retinoic acid receptor beta in human epidermoid lung cancer cells

21 January 2018

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Methylation and silencing of the retinoic acid receptor-beta 2 gene in cervical cancer

21 January 2018

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Histone-deacetylase inhibitors: novel drugs for the treatment of cancer

21 January 2018

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Reactivating the expression of methylation silenced genes in human cancer

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

Lung cancer chemoprevention

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

UBE1L is a retinoid target that triggers PML/RARalpha degradation and apoptosis in acute promyelocytic leukemia

21 January 2018

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4HPR triggers apoptosis but not differentiation in retinoid sensitive and resistant human embryonal carcinoma cells through an RARgamma independent pathway

21 January 2018

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Selectivity of chromatin-remodelling cofactors for ligand-activated transcription

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

Genomic and proteomic analysis of the myeloid differentiation program

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

AML1 and the AML1-ETO fusion protein in the pathogenesis of t(8;21) AML.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

Acquisition of oncogenic potential by RAR chimeras in acute promyelocytic leukemia through formation of homodimers.

21 January 2018

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Role of the histone deacetylase complex in acute promyelocytic leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

Randomized phase III intergroup trial of isotretinoin to prevent second primary tumors in stage I non-small-cell lung cancer

21 January 2018

1 reference

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Suppression of retinoic acid receptor-beta in premalignant oral lesions and its up-regulation by isotretinoin.

21 January 2018

1 reference

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Synergistic cytotoxicity in solid tumor cell lines between N-(4-hydroxyphenyl)retinamide and modulators of ceramide metabolism

21 January 2018

1 reference

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Regulation of retinoic acid signaling in the embryonic nervous system: a master differentiation factor

21 January 2018

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DNA methyltransferase inhibition induces the transcription of the tumor suppressor p21(WAF1/CIP1/sdi1).

21 January 2018

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Evidence for impaired retinoic acid receptor-thyroid hormone receptor AF-2 cofactor activity in human lung cancer

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

Characterization of two novel retinoic acid-resistant cell lines derived from HL-60 cells following long-term culture with all-trans-retinoic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

Transcriptional coactivator complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

The role of epigenetic modifications in retinoic acid receptor beta2 gene expression in human prostate cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

Common defects of different retinoic acid resistant promyelocytic leukemia cells are persistent telomerase activity and nuclear body disorganization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

Targeting the PML/RAR alpha translocation product triggers apoptosis in promyelocytic leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

Modulation of docetaxel-induced apoptosis and cell cycle arrest by all- trans retinoic acid in prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

Cytochrome p450 retinoic acid 4-hydroxylase inhibitors: potential agents for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

Tumor prevention by 9-cis-retinoic acid in the N-nitroso-N-methylurea model of mammary carcinogenesis is potentiated by the pineal hormone melatonin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

Liposomal-all-trans-retinoic acid in treatment of acute promyelocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

Transcription therapy for cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

A novel mechanism of retinoic acid resistance in acute promyelocytic leukemia cells through a defective pathway in telomerase regulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

Complete remission through blast cell differentiation in PLZF/RARalpha-positive acute promyelocytic leukemia: in vitro and in vivo studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

Expression of Retinoid Receptor Genes and Proteins in Non-Small-Cell Lung Cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

Loss of retinoic acid receptor-beta expression is an early event during esophageal carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

Mediator complexes and transcription.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

Ligand-dependent transcription activation by nuclear receptors requires the DRIP complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

Retinoid X receptor and its partners in the nuclear receptor family

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

Retinoid therapy of childhood cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

Retinoic-acid-resistant neuroblastoma cell lines show altered MYC regulation and high sensitivity to fenretinide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

DNMT1 is required to maintain CpG methylation and aberrant gene silencing in human cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

Coregulator codes of transcriptional regulation by nuclear receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

RAR beta 2-mediated growth inhibition in HeLa cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

Randomized controlled trial of azacitidine in patients with the myelodysplastic syndrome: a study of the cancer and leukemia group B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

Specific retinoid receptors cooperate to signal growth suppression and maturation of human embryonal carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

Retinoids and their receptors in cancer development and chemoprevention

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

Role of P-glycoprotein in all-trans retinoic acid (ATRA) resistance in acute promyelocytic leukaemia cells: analysis of intracellular concentration of ATRA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

Management of acute promyelocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

Interpreting patterns of gene expression with self-organizing maps: methods and application to hematopoietic differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

Fenretinide and cancer prevention

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

RARbeta2 specificity in mediating RA inhibition of growth of lung cancer-derived cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

Retinoic acid resistance of estradiol-independent breast cancer cells coincides with diminished retinoic acid receptor function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

Inhibition of all-TRANS-retinoic acid metabolism by R116010 induces antitumour activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

Recruitment of the SWI-SNF chromatin remodeling complex as a mechanism of gene activation by the glucocorticoid receptor tau1 activation domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

cDNA cloning of human retinoic acid-metabolizing enzyme (hP450RAI) identifies a novel family of cytochromes P450

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

Methylation and silencing of the retinoic acid receptor-beta2 gene in breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

TISSUE CHANGES FOLLOWING DEPRIVATION OF FAT-SOLUBLE A VITAMIN

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

Modulation of retinoic acid sensitivity in lung cancer cells through dynamic balance of orphan receptors nur77 and COUP-TF and their heterodimerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

Coactivator and corepressor complexes in nuclear receptor function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

A transcriptional switch mediated by cofactor methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

Suppression of retinoic acid receptor beta in non-small-cell lung cancer in vivo: implications for lung cancer development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

Translocations of the RARalpha gene in acute promyelocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

Frequent mutations in the ligand-binding domain of PML-RARalpha after multiple relapses of acute promyelocytic leukemia: analysis for functional relationship to response to all-trans retinoic acid and histone deacetylase inhibitors in vitro and in v

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

Selective estrogen receptor modulators (SERMs) and retinoids in breast cancer chemoprevention

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

Promoter Methylation and Silencing of the Retinoic Acid Receptor- Gene in Lung Carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

Pilot trial of the safety, tolerability, and retinoid levels of N-(4-hydroxyphenyl) retinamide in combination with tamoxifen in patients at high risk for developing invasive breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

inferred from DOI database lookup

7 January 2021

based on heuristic

Activation of the retinoic acid receptor beta gene by 5-aza-2'-deoxycytidine in human DLD-1 colon carcinoma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

inferred from DOI database lookup

7 January 2021

based on heuristic

Demethylation by 5-aza-2'-deoxycytidine of specific 5-methylcytosine sites in the promoter region of the retinoic acid receptor beta gene in human colon carcinoma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206936

inferred from DOI database lookup

7 January 2021

based on heuristic

Lung tumors in mice expressing an antisense RARbeta2 transgene

series ordinal

4

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206936

The treatment of cutaneous T-cell lymphoma with a novel retinoid.

24 March 2024

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44

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206936

24 March 2024

Identifiers

1 reference

8 August 2017

1 reference